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Browse our anti-SIRT1 (SIRT1) Antibodies

Full name:
anti-Sirtuin 1 Antibodies (SIRT1)
On www.antibodies-online.com are 278 Sirtuin 1 (SIRT1) Antibodies from 35 different suppliers available. Additionally we are shipping SIRT1 Kits (31) and SIRT1 Proteins (22) and many more products for this protein. A total of 338 SIRT1 products are currently listed.
Synonyms:
AA673258, SIR2, Sir2a, Sir2alpha, sir2l1, sirtuin, sirtuin 1
list all antibodies Gene Name GeneID UniProt
SIRT1 93759 Q923E4
SIRT1 23411 Q96EB6
SIRT1 309757  

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Most Popular Reactivities for anti-SIRT1 (SIRT1) Antibodies

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anti-Mouse (Murine) SIRT1 Antibodies:

anti-Human SIRT1 Antibodies:

anti-Rat (Rattus) SIRT1 Antibodies:

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Top referenced anti-SIRT1 Antibodies

  1. Human Monoclonal SIRT1 Primary Antibody for WB - ABIN1882053 : Vaziri, Dessain, Ng Eaton, Imai, Frye, Pandita, Guarente, Weinberg: hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. in Cell 2001 (PubMed)
    Show all 5 references for ABIN1882053

  2. Chicken Polyclonal SIRT1 Primary Antibody for WB - ABIN2779607 : Solomon, Pasupuleti, Xu, McDonagh, Curtis, DiStefano, Huber: Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. in Molecular and cellular biology 2005 (PubMed)
    Show all 4 references for ABIN2779607

  3. Human Polyclonal SIRT1 Primary Antibody for IF (p), IHC (p) - ABIN745658 : Suzuki, Bartlett: Sirtuin1 and autophagy protect cells from fluoride-induced cell stress. in Biochimica et biophysica acta 2014 (PubMed)
    Show all 2 references for ABIN745658

  4. Human Monoclonal SIRT1 Primary Antibody for ICC, FACS - ABIN969396 : Xie, Park, Kim, Hwang, Oh, Park, Shong, Lee, Choi: Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 references for ABIN969396

  5. Human Monoclonal SIRT1 Primary Antibody for ICC, IF - ABIN2668278 : Rajendran, Kidane, Yu, Dashwood, Bisson, Löhr, Ho, Williams, Dashwood: HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates. in Epigenetics 2013 (PubMed)
    Show all 2 references for ABIN2668278

  6. Dog (Canine) Polyclonal SIRT1 Primary Antibody for WB - ABIN2779608 : Anavekar, Mirza, Skali, Plappert, St John Sutton, Pfeffer, Solomon,: Risk assessment in patients with depressed left ventricular function after myocardial infarction using the myocardial performance index--Survival and Ventricular Enlargement (SAVE) experience. in Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2006 (PubMed)
    Show all 2 references for ABIN2779608

  7. Mouse (Murine) Polyclonal SIRT1 Primary Antibody for ELISA, WB - ABIN185702 : Chen, Steele, Lindquist, Guarente: Increase in activity during calorie restriction requires Sirt1. in Science (New York, N.Y.) 2005 (PubMed)
    Show all 2 references for ABIN185702

  8. Human Polyclonal SIRT1 Primary Antibody for EIA, WB - ABIN783610 : Afshar, Murnane: Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2. in Gene 1999 (PubMed)

  9. Human Polyclonal SIRT1 Primary Antibody for IF (p), IHC (p) - ABIN729853 : Mohan, Kumar, Lackner, Alvarez: Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques. in Journal of immunology (Baltimore, Md. : 1950) 2014 (PubMed)

More Antibodies against SIRT1 Interaction Partners

Rabbit Sirtuin 1 (SIRT1) interaction partners

  1. SIRT1 signaling pathway may be targeted for therapeutic intervention in flexor tendon injury.

Mouse (Murine) Sirtuin 1 (SIRT1) interaction partners

  1. Inhibiting Sirtuin-1 can be a useful asset in controlling T-cell-mediated rejection in murine model of kidney transplantation.

  2. SIRT1 overexpression and caloric restriction both improve glucose metabolism and insulin (show INS Antibodies) sensitivity, however, the etiologies of these benefits are largely different.

  3. Study shows that mTORC1 signaling in intestinal stem cells (ISCs (show NFS1 Antibodies)) is instead upregulated during calorie restriction; SIRT1 deacetylates S6K1 (show RPS6KB1 Antibodies), thereby enhancing its phosphorylation by mTORC1, which leads to an increase in protein synthesis and an increase in ISC number.

  4. SIRT1 promoted the stability of NRF2 (show NFE2L2 Antibodies) by regulating the deacetylation and activation of the NRF2 (show NFE2L2 Antibodies)/ARE antioxidant pathway.

  5. In summary, SIRT1 reduced histopathologic injury, apoptosis, oxidative stress, and the inflammatory response during hepatic ischemia reperfusion injury, and the protective mechanisms of SIRT1 are involved in the activation of the JNK (show MAPK8 Antibodies), p38MAPK (show MAPK14 Antibodies), and ERK (show EPHB2 Antibodies) kinases before ischemia

  6. A novel regulatory mechanism was found in which Sirt1 antisense long non-coding RNA preferably interacted with Sirt1 mRNA forming RNA duplex to promote Sirt1 ranslation by competing with miR (show MLXIP Antibodies)-34a, inhibiting muscle formation.

  7. Treatment of the cells with ursolic acid (UA) showed that UA up-regulated SIRT1 ( approximately 35 folds) and overexpressed PGC-1alpha (show PPARGC1A Antibodies) ( approximately 175 folds) gene significantly.

  8. the SIRT1-mediated pathway is a promising target for the treatment of intestinal INTESTINAL ISCHEMIA-REPERFUSION.

  9. ALDH2 (show ALDH2 Antibodies) enhanced SIRT1 regulates LC3 (show MAP1LC3A Antibodies)-Atg7 (show ATG7 Antibodies) interaction and FoxO1 (show FOXO1 Antibodies) increased Rab7 (show RAB7A Antibodies) expression, which were both necessary and sufficient for restoring autophagy flux.

  10. Pharmacologic activation of SIRT1 modulates the innate host response and could represent a novel treatment strategy for severe infection.

Human Sirtuin 1 (SIRT1) interaction partners

  1. Potential role of SIRT1 in association with EMT (show ITK Antibodies)-related factors on tumor invasion, metastasis, and disease-free survival in triple negative breast cancer.

  2. OA treatment represses SIRT1 and peroxisome proliferator-activated receptors-gamma levels in SMCs.

  3. Data show that sirtuin 1 protein (SIRT1) mRNA expression in peripheral blood leukocytes (PBLs) significantly decreased 0.37-fold after granulocyte-colony stimulating factor (G-CSF (show CSF3 Antibodies)) administration.

  4. the regulation of MMP9 (show MMP9 Antibodies) was mediated in a SIRT-1 dependent mechanism and did not alter the NFkB signaling pathway.

  5. Brachyury (show TBX1 Antibodies) mediates tamoxifen resistance by regulating Sirtuin-1 in breast cancer cells.

  6. Altered expression of the SIRT1 protein regulating miR (show MLXIP Antibodies)-199a in human atrial tissue was found to be related to the occurrence of postoperative atrial fibrillation

  7. miR (show MLXIP Antibodies)-204-5p and SIRT1 may play an important role in the development of hepatocellular carcinoma.

  8. SIRT-1 and NANOG are high correlated biological markers for diagnosis and prognosis follow up in patients with adenocarcinoma.

  9. Leptin (show LEP Antibodies) and SIRT1 expressions are significantly associated with shorter overall survival of osteosarcoma patients, and SIRT1 expression is a significant independent prognostic indicator in patients with osteosarcoma.

  10. The results of this study suggest that calorie restriction might override the genetic contributions of the SIRT1 rs7895833 A and rs1467568 G alleles to BMI and long-term weight change.

Pig (Porcine) Sirtuin 1 (SIRT1) interaction partners

  1. Combining the in vivo and in vitro results, the effect of SIRT1 in granulosa cells apoptosis during follicular atresia was identified.

  2. SIRT1, p53 (show TP53 Antibodies) and NF-kappaB (show NFKB1 Antibodies) are involved in the control of both the proliferation and the apoptosis of ovarian cells.

  3. the expression of SIRT1 is associated with the Mt number in oocytes

  4. Resveratrol activated sirtuin 1 (Sirt1) gene expression and increased adipose triglyceride lipase (ATGL (show PNPLA2 Antibodies)) gene expression and glycerol release. Furthermore, this study found the opposite Sirt1 regulation pattern for PPARgamma (show PPARG Antibodies) to that of ATGL (show PNPLA2 Antibodies) in adipocytes.

  5. CDK5 (show CDK5 Antibodies)-mediated hyperphosphorylation of SIRT1 facilitates the development of endothelial senescence and atherosclerosis.

  6. SIRT1 and LKB1 (show STK11 Antibodies)/AMPK (show PRKAA1 Antibodies) are the 2 key sensor systems for regulating endothelial cell survival, proliferation and senescence.

  7. Sirt1 may down-regulate pig preadipocytes proliferation and differentiation through repression of adipocyte genes or FoxO1 (show FOXO1 Antibodies).

  8. The full-length complementary DNA sequence of porcine Sirt1 was 4,024 bp (GenBank accession no: EU030283), with a 2,226-bp open reading frame encoding a 742-AA protein

  9. Downregulation of miR (show MYLIP Antibodies)-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes.

  10. Sirt1 regulates the expression of FABP3 (show FABP3 Antibodies) gene in adipocytes, and PPAR gamma (show PPARG Antibodies) apparently plays an important role in this process.

Cow (Bovine) Sirtuin 1 (SIRT1) interaction partners

  1. The results indicate that the variations in the class I sirtuin genes and their corresponding genotypes may be considered as molecular markers for economic traits in cattle breeding.

  2. These results suggest that the SIRT1 gene could be used in marker assisted selection to improve the production traits of Qinchuan cattle.

  3. Downregulation of SIRT1 and FoxO1 (show FOXO1 Antibodies) were observed in the backfat tissue of Lilu cattle with increasing age. SIRT1 may play an important role in the development of bovine adipose tissue.

  4. Study indicates that a variation in the SIRT1 gene, the c.-274G variant in the promoter region, is associated with greater body size in Nanyang cattle.

  5. 5 novel SNPs were found in SIRT1. SNP g.-274C>G was shown to have association with 24-months-old body weight and g.17379A>G polymorphism was significantly related to 6 and 12-months-old body weight in NY population; results provide evidence that polymorphisms in SIRT1 are associated with growth efficiency traits

  6. The expression profile of sirtuin 1 and sirtuin 3 (show SIRT3 Antibodies) in the liver, muscle, and adipose tissue of calves and bulls is reported.

SIRT1 Antigen Profile

Antigen Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with SIRT1

  • sirtuin 1 (SIRT1) antibody
  • sirtuin 1 (SRT1) antibody
  • sirtuin 1 (LOC100349271) antibody
  • sirtuin 1 (Sirt1) antibody
  • sirtuin 1 (sirt1) antibody
  • AA673258 antibody
  • SIR2 antibody
  • Sir2a antibody
  • Sir2alpha antibody
  • sir2l1 antibody
  • sirtuin antibody
  • sirtuin 1 antibody

Protein level used designations for anti-Sirtuin 1 (SIRT1) Antibodies

sirtuin 1 , NAD-dependent deacetylase sirtuin-1 , NAD-dependent protein deacetylase sirtuin-1 , SIR2-like protein 1 , mSIR2a , regulatory protein SIR2 homolog 1 , sir2-like 1 , sirtuin 1 ((silent mating type information regulation 2, homolog) 1 , SIR2alpha , hSIR2 , hSIRT1 , sirtuin type 1 , sirtuin (silent mating type information regulation 2 homolog) 1 , NAD-dependent deacetylase sirtuin 1 , sirtuin1 , Sir2alpha

GENE ID SPECIES
100072571 Equus caballus
835670 Arabidopsis thaliana
100349271 Oryctolagus cuniculus
100540948 Meleagris gallopavo
100605499 Nomascus leucogenys
93759 Mus musculus
23411 Homo sapiens
100036963 Xenopus laevis
423646 Gallus gallus
489012 Canis lupus familiaris
751859 Sus scrofa
309757 Rattus norvegicus
101087610 Felis catus
613629 Bos taurus
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