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Browse our anti-SIRT1 (SIRT1) Antibodies

Full name:
anti-Sirtuin 1 Antibodies (SIRT1)
On are 274 Sirtuin 1 (SIRT1) Antibodies from 35 different suppliers available. Additionally we are shipping SIRT1 Kits (30) and SIRT1 Proteins (22) and many more products for this protein. A total of 333 SIRT1 products are currently listed.
AA673258, SIR2, Sir2a, Sir2alpha, sir2l1, sirtuin, sirtuin 1
list all antibodies Gene Name GeneID UniProt
SIRT1 93759 Q923E4
SIRT1 23411 Q96EB6
SIRT1 309757  

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Most Popular Reactivities for anti-SIRT1 (SIRT1) Antibodies

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anti-Mouse (Murine) SIRT1 Antibodies:

anti-Human SIRT1 Antibodies:

anti-Rat (Rattus) SIRT1 Antibodies:

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Top referenced anti-SIRT1 Antibodies

  1. Human Monoclonal SIRT1 Primary Antibody for WB - ABIN1882053 : Vaziri, Dessain, Ng Eaton, Imai, Frye, Pandita, Guarente, Weinberg: hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. in Cell 2001 (PubMed)
    Show all 5 references for ABIN1882053

  2. Chicken Polyclonal SIRT1 Primary Antibody for WB - ABIN2779607 : Solomon, Pasupuleti, Xu, McDonagh, Curtis, DiStefano, Huber: Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. in Molecular and cellular biology 2005 (PubMed)
    Show all 4 references for ABIN2779607

  3. Human Polyclonal SIRT1 Primary Antibody for IF (p), IHC (p) - ABIN745658 : Suzuki, Bartlett: Sirtuin1 and autophagy protect cells from fluoride-induced cell stress. in Biochimica et biophysica acta 2014 (PubMed)
    Show all 2 references for ABIN745658

  4. Human Monoclonal SIRT1 Primary Antibody for ICC, FACS - ABIN969396 : Xie, Park, Kim, Hwang, Oh, Park, Shong, Lee, Choi: Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 references for ABIN969396

  5. Human Monoclonal SIRT1 Primary Antibody for ICC, IF - ABIN2668278 : Rajendran, Kidane, Yu, Dashwood, Bisson, Löhr, Ho, Williams, Dashwood: HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates. in Epigenetics 2013 (PubMed)
    Show all 2 references for ABIN2668278

  6. Dog (Canine) Polyclonal SIRT1 Primary Antibody for WB - ABIN2779608 : Anavekar, Mirza, Skali, Plappert, St John Sutton, Pfeffer, Solomon,: Risk assessment in patients with depressed left ventricular function after myocardial infarction using the myocardial performance index--Survival and Ventricular Enlargement (SAVE) experience. in Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2006 (PubMed)
    Show all 2 references for ABIN2779608

  7. Mouse (Murine) Polyclonal SIRT1 Primary Antibody for ELISA, WB - ABIN185702 : Chen, Steele, Lindquist, Guarente: Increase in activity during calorie restriction requires Sirt1. in Science (New York, N.Y.) 2005 (PubMed)
    Show all 2 references for ABIN185702

  8. Human Polyclonal SIRT1 Primary Antibody for EIA, WB - ABIN783610 : Afshar, Murnane: Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2. in Gene 1999 (PubMed)

  9. Human Polyclonal SIRT1 Primary Antibody for IF (p), IHC (p) - ABIN729853 : Mohan, Kumar, Lackner, Alvarez: Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques. in Journal of immunology (Baltimore, Md. : 1950) 2014 (PubMed)

More Antibodies against SIRT1 Interaction Partners

Rabbit Sirtuin 1 (SIRT1) interaction partners

  1. SIRT1 signaling pathway may be targeted for therapeutic intervention in flexor tendon injury.

Mouse (Murine) Sirtuin 1 (SIRT1) interaction partners

  1. indicated that melatonin facilitated AD-MSCs-based therapy in MI, possibly through promoting survival of AD-MSCs via SIRT1 signaling.

  2. results shed novel insight into CML LSCs and support a crucial role of SIRT1 in CML LSCs.

  3. HDAC4 (show HDAC5 Antibodies) increases endogenous SIRT1 expression by enhancing its sumoylation modification levels

  4. In the cochlea, the expression of SIRT1, 3, and 5 (both mRNA and protein) was decreased in the old mice

  5. SIRT1 overexpression substantially increased autophagy in wild-type cells, but not in MFN2 (show MFN2 Antibodies)-deficient cells.

  6. overexpression of miR (show MLXIP Antibodies)-27b could benefit mitochondrial function, the effects of overexpressed miR (show MLXIP Antibodies)-27b were Sirt1-dependent.

  7. The acetylation-dependent interaction between HMGB1 (show HMGB1 Antibodies) and SIRT1 is critical for LPS (show TLR4 Antibodies)-induced lethality.

  8. Demonstrate that cardiac Sirt1 plays an essential role in caloritc restriction-induced cardioprotection against myocardial I/R injury by suppressing cardiac C3 expression.

  9. SIRT1 and the axis AII (show ARG2 Antibodies)/AT1 (show SLC33A1 Antibodies)/NADPH-oxidase (show NOX1 Antibodies) regulate each other

  10. Long-lasting exposure to ox-LDL decreases the expression of Sirt1 and Runx2 (show RUNX2 Antibodies) in bone mesenchymal stem cells which may explain the decreased bone formation in aged apoE (show APOE Antibodies)(-/-) mice.

Human Sirtuin 1 (SIRT1) interaction partners

  1. In Hodgkin lymphoma infiltrating lymphocytes, there was a difference of Sirt1 to FoxP3 (show FOXP3 Antibodies) ratios between remission and recurrence groups, being significantly higher in the recurrence group

  2. Data suggest that activation of SIRT1 may improve insulin (show INS Antibodies) sensitivity of liver, skeletal muscle, and adipose tissues and protect function and cell mass of pancreatic beta-cells. [REVIEW]

  3. HDAC4 (show HDAC4 Antibodies) increases endogenous SIRT1 expression by enhancing its sumoylation modification levels

  4. myeloid cell-specific deletion of SIRT1 appeared to suppress CIA (show ASF1A Antibodies) by modulating DC maturation.

  5. Findings showed that miR (show MLXIP Antibodies)-22 functioned as tumor suppressor in renal cell carcinoma (show MOK Antibodies) (RCC (show XRCC1 Antibodies)) and blocked RCC (show XRCC1 Antibodies) growth and metastasis by directly targeting SIRT1.

  6. Our findings indicate that phosphorylation-dependent restriction of SIRT1 activity by HIPK2 (show HIPK2 Antibodies) shapes the p53 (show TP53 Antibodies) response

  7. SIRT1 overexpression in iPSC-endothelial cells maintains EC phenotype, improves EC function, and extends cell lifespan.

  8. inhibitory effect of RSV on the HIF-1alpha (show HIF1A Antibodies)/VEGF (show VEGFA Antibodies)/VEGFR2 (show KDR Antibodies) signaling axis is mediated, at least in part, through SIRT1

  9. Studies indicate that when NAD+ levels drop, SIRT1 protein activity is reduced, leading to mitochondrial dysfunction.

  10. SIRT1-mediated mitochondrial and Akt (show AKT1 Antibodies) pathways have roles in glioblastoma cell death induced by Cotinus coggygria flavonoid nanoliposomes

Pig (Porcine) Sirtuin 1 (SIRT1) interaction partners

  1. Combining the in vivo and in vitro results, the effect of SIRT1 in granulosa cells apoptosis during follicular atresia was identified.

  2. SIRT1, p53 (show TP53 Antibodies) and NF-kappaB (show NFKB1 Antibodies) are involved in the control of both the proliferation and the apoptosis of ovarian cells.

  3. the expression of SIRT1 is associated with the Mt number in oocytes

  4. Resveratrol activated sirtuin 1 (Sirt1) gene expression and increased adipose triglyceride lipase (ATGL (show PNPLA2 Antibodies)) gene expression and glycerol release. Furthermore, this study found the opposite Sirt1 regulation pattern for PPARgamma (show PPARG Antibodies) to that of ATGL (show PNPLA2 Antibodies) in adipocytes.

  5. CDK5 (show CDK5 Antibodies)-mediated hyperphosphorylation of SIRT1 facilitates the development of endothelial senescence and atherosclerosis.

  6. SIRT1 and LKB1 (show STK11 Antibodies)/AMPK (show PRKAA1 Antibodies) are the 2 key sensor systems for regulating endothelial cell survival, proliferation and senescence.

  7. Sirt1 may down-regulate pig preadipocytes proliferation and differentiation through repression of adipocyte genes or FoxO1 (show FOXO1 Antibodies).

  8. The full-length complementary DNA sequence of porcine Sirt1 was 4,024 bp (GenBank accession no: EU030283), with a 2,226-bp open reading frame encoding a 742-AA protein

  9. Downregulation of miR (show MYLIP Antibodies)-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes.

  10. Sirt1 regulates the expression of FABP3 (show FABP3 Antibodies) gene in adipocytes, and PPAR gamma (show PPARG Antibodies) apparently plays an important role in this process.

Cow (Bovine) Sirtuin 1 (SIRT1) interaction partners

  1. The results indicate that the variations in the class I sirtuin genes and their corresponding genotypes may be considered as molecular markers for economic traits in cattle breeding.

  2. These results suggest that the SIRT1 gene could be used in marker assisted selection to improve the production traits of Qinchuan cattle.

  3. Downregulation of SIRT1 and FoxO1 (show FOXO1 Antibodies) were observed in the backfat tissue of Lilu cattle with increasing age. SIRT1 may play an important role in the development of bovine adipose tissue.

  4. Study indicates that a variation in the SIRT1 gene, the c.-274G variant in the promoter region, is associated with greater body size in Nanyang cattle.

  5. 5 novel SNPs were found in SIRT1. SNP g.-274C>G was shown to have association with 24-months-old body weight and g.17379A>G polymorphism was significantly related to 6 and 12-months-old body weight in NY population; results provide evidence that polymorphisms in SIRT1 are associated with growth efficiency traits

  6. The expression profile of sirtuin 1 and sirtuin 3 (show SIRT3 Antibodies) in the liver, muscle, and adipose tissue of calves and bulls is reported.

SIRT1 Antigen Profile

Antigen Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with SIRT1

  • sirtuin 1 (SIRT1) antibody
  • sirtuin 1 (SRT1) antibody
  • sirtuin 1 (LOC100349271) antibody
  • sirtuin 1 (Sirt1) antibody
  • sirtuin 1 (sirt1) antibody
  • AA673258 antibody
  • SIR2 antibody
  • Sir2a antibody
  • Sir2alpha antibody
  • sir2l1 antibody
  • sirtuin antibody
  • sirtuin 1 antibody

Protein level used designations for anti-Sirtuin 1 (SIRT1) Antibodies

sirtuin 1 , NAD-dependent deacetylase sirtuin-1 , NAD-dependent protein deacetylase sirtuin-1 , SIR2-like protein 1 , mSIR2a , regulatory protein SIR2 homolog 1 , sir2-like 1 , sirtuin 1 ((silent mating type information regulation 2, homolog) 1 , SIR2alpha , hSIR2 , hSIRT1 , sirtuin type 1 , sirtuin (silent mating type information regulation 2 homolog) 1 , NAD-dependent deacetylase sirtuin 1 , sirtuin1 , Sir2alpha

100072571 Equus caballus
835670 Arabidopsis thaliana
100349271 Oryctolagus cuniculus
100540948 Meleagris gallopavo
100605499 Nomascus leucogenys
93759 Mus musculus
23411 Homo sapiens
100036963 Xenopus laevis
423646 Gallus gallus
489012 Canis lupus familiaris
751859 Sus scrofa
309757 Rattus norvegicus
101087610 Felis catus
613629 Bos taurus
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