Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SIRT1 Products

(Sirtuin 1 (SIRT1))
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured SIRT1 Categories

SIRT1 Antibodies

High quality antibodies with extensive validation data.

SIRT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SIRT1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SIRT1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (5)
  • (7)
Cat. No. ABIN729853
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (5)
  • (4)
Cat. No. ABIN2779607
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF, IHC, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3032583
Quantity 0.4 mL
Datasheet Datasheet

Recommended SIRT1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (8)
  • (1)
Cat. No. ABIN6959485
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN6959487
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970227
Quantity 96 tests
Datasheet Datasheet

Recommended SIRT1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136886
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095388
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136887
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SIRT1 products

Zbroch, Bazyluk, Malyszko, Koc-Zorawska, Rydzewska-Rosolowska, Kakareko, Hryszko: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." in: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).

Yang, Wang, He, Liu, Chen, Wang, Wang, Wang: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." in: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).

Ascenzi, Barberi, Dobrowolny, Villa Nova Bacurau, Nicoletti, Rizzuto, Rosenthal, Scicchitano, Musarò: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." in: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).

Takata, Sakasai-Sakai, Takino, Takeuchi: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." in: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Zhang, Abdukerim, Abilailieti, Tang, Ling, Pan: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." in: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).

Ar Rochmah, Harini, Septyaningtrias, Sari, Susilowati: "Centella asiatica Prevents Increase of Hippocampal Tumor Necrosis Factor-α Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of Chronic Stress." in: BioMed research international, Vol. 2019, pp. 2649281, (2019) (PubMed).

Hou, Su, Chen, Niu, Zhao, Wang, Shen: "Association of SIRT1 gene polymorphism and its expression for the risk of alcoholic fatty liver disease in the Han population." in: Hepatology international, Vol. 12, Issue 1, pp. 56-66, (2018) (PubMed).

Piao, Zhao, Zhu, Inoue, Shibata, Lei, Hu, Yu, Yang, Wu, Xu, Okumura, Ouchi, Murohara, Kuzuya, Cheng: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Zang, Fan, Chen, Huang, Qin: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).

Synonyms and alternative names related to SIRT1

sirtuin 1 (SIRT1), sirtuin 1 (SRT1), sirtuin 1 (Sirt1), sirtuin 1 L homeolog (sirt1.L), AA673258, Sir2, SIR2, Sir2a, Sir2alpha, SIR2L1, sir2l1, sirtuin, sirtuin 1

Protein level used designations for SIRT1

  • sirtuin 1
  • NAD-dependent deacetylase sirtuin-1
  • NAD-dependent protein deacetylase sirtuin-1
  • SIR2-like protein 1
  • mSIR2a
  • regulatory protein SIR2 homolog 1
  • sir2-like 1
  • sirtuin 1 ((silent mating type information regulation 2, homolog) 1
  • SIR2alpha
  • hSIR2
  • hSIRT1
  • sirtuin type 1
  • sirtuin (silent mating type information regulation 2 homolog) 1
  • NAD-dependent deacetylase sirtuin 1
  • sirtuin1
  • Sir2alpha
You are here:
Support