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anti-Human KIF2B Antibodies:
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Human Polyclonal KIF2B Primary Antibody for WB - ABIN2778254
Manning, Ganem, Bakhoum, Wagenbach, Wordeman, Compton: The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. in Molecular biology of the cell 2007
Show all 2 references for ABIN2778254
Data indicate that Cep170 (show CEP170 Antibodies) association with the C-terminus of Kif2b enhances localization of Kif2b to the spindle.
Data show that Polo-like kinase 1 (Plk1 (show PLK1 Antibodies)) regulates both the localization and activity of kinesin-13 protein Kif2b during mitosis to promote the correction of k-MT attachment errors to ensure mitotic fidelity.
Data show that CLASP1 (show CLASP1 Antibodies)-astrin (show SPAG5 Antibodies)-Kif2b complex acts as a central switch at kinetochores that defines mitotic progression and promotes fidelity by temporally regulating kinetochore-microtuble attachments.
when microtubules are absent, the neck linker exists in equilibrium between two structural states; microtubule binding may activate the nucleotide-sensing mechanism of kinesin
kinesin-I-dependent neuronal AbetaPP transport, which controls AbetaPP processing, may be regulated by JIP1 (show MAPK8IP1 Antibodies)
These data demonstrate that Kif2b function is required for spindle assembly and chromosome movement and that the microtubule depolymerase activities of Kif2a (show KIF2A Antibodies), Kif2b, and MCAK (show KIF2C Antibodies) fulfill distinct functions during mitosis in human cells.
Here we show that two microtubule-depolymerizing kinesins, Kif2b and MCAK (show KIF2C Antibodies), stimulate kinetochore-microtubule dynamics during distinct phases of mitosis to correct mal (show MAL Antibodies)-orientations.
Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement during mitosis. Has microtubule depolymerization activity (By similarity).
kinesin family member 2B
, kinesin protein
, kinesin-like protein KIF2B-like
, kinesin-like protein KIF2B