KIF2B antibody (Middle Region)

Catalog No. ABIN2778254

This Rabbit Polyclonal antibody specifically detects KIF2B in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Horse, Cow and Zebrafish (Danio rerio).It has been mentioned in 1 publication

Quick Overview for KIF2B antibody (Middle Region) (ABIN2778254)

Target: KIF2B (Kinesin Family Member 2B (KIF2B))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Horse, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KIF2B Antibody

Binding Specificity: Middle Region

Purpose: KIF2B Antibody - middle region

Sequence: DCSKGIYALV AQDVFLLLRN STYEKLDLKV YGTFFEIYGG KVYDLLNWKK

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against KIF2B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KIF2B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34082-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-KIF2B antibody (ABIN2778254)

Shrestha, Draviam: "Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK." in: Current biology : CB, Vol. 23, Issue 16, pp. 1514-26, (2013) (PubMed).

Target Details for KIF2B

Target: KIF2B (Kinesin Family Member 2B (KIF2B))

Alternative Name: KIF2B

Background:

Background Information: KIF2B is the plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. KIF2B has microtubule depolymerization activity.

Gene Name: Kinesin family member 2B

Alternative Symbols: -

Protein Name: Kinesin-like protein KIF2B

Molecular Weight: 76kDa

Gene ID: 84643

NCBI Accession: NP_115948

UniProt: Q8N4N8

Pathways: Microtubule Dynamics