Browse our Actin, gamma 1 Proteins (ACTG1)

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Actin, gamma 1 Proteins (ACTG1)
On are 18 Actin, gamma 1 (ACTG1) Proteins from 8 different suppliers available. Additionally we are shipping Actin, gamma 1 Antibodies (90) and Actin, gamma 1 Kits (22) and many more products for this protein. A total of 134 Actin, gamma 1 products are currently listed.
ACT, actbb, Actg, actg1a, actg1b, actin, Actl, AL023024, bact2, bactin2, BRWS2, cytoplasmic, DFNA20, DFNA26, E51, fa56g06, fb38a10, wu:fa56g06, wu:fb38a10
list all proteins Gene Name GeneID UniProt
ACTG1 71 P63261
ACTG1 287876 P63259
ACTG1 11465 P63260

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Actin, gamma 1 Proteins (ACTG1) by Origin

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Zebrafish Actin, gamma 1 (ACTG1) interaction partners

Human Actin, gamma 1 (ACTG1) interaction partners

  1. Data indicate that F-actin is significantly elevated in septic shock, and F-actin and the F:G-actin ratio are potential biomarkers for the diagnosis of septic shock.

  2. a novel mutation in ACTG1 was found to be co-segregated with hearing loss and the genetic cause of autosomal dominant nonsyndromic hearing impairment in a Chinese family

  3. Three unrelated cases of rare ACTG1 variants in fetal microlissencephaly have been described.

  4. In this study we sought to clarify the detailed mutational spectrum, clinical features, and genotype-phenotype correlations for ACTG1 gene associated autosomal dominant sensorineural hearing loss

  5. Mutations in ACTB (show ACTB Proteins) cause a distinctly more severe phenotype than ACTG1 mutations in Baraitser-Winter syndrome.

  6. The data, for the first time, link ASAP3 (show ASAP3 Proteins) with ACTG1 in the regulation of cytoskeletal maintenance and cell motility

  7. The actin/MKL1 signalling pathway influences cell growth and gene expression through large-scale chromatin reorganization and histone post-translational modifications.

  8. the novel variant p.M305T in ACTG1 (DFNA20/26) was selected as a disease-causing variant.

  9. These results showed the biphasic F-actin dynamics in herpes simplex virus 1 neuronal infection and confirmed the association of F-actin with the changes in the expression and activity of cofilin 1 (show CFL1 Proteins).

  10. identified de novo missense changes in the cytoplasmic actin-encoding genes ACTB (show ACTB Proteins) and ACTG1 in one and two probands, respectively; suggest that Baraitser-Winter syndrome is the predominant phenotype associated with mutation of these two genes

Cow (Bovine) Actin, gamma 1 (ACTG1) interaction partners

  1. Data indicate that the complex formation of actin by thymosin beta4 is more likely to be flexible than rigid and is localized along the subdomains 1 to 3 of actin.

Mouse (Murine) Actin, gamma 1 (ACTG1) interaction partners

  1. Two actin isoforms, beta- and gamma-actin, are crucial for slow, rapid, bulk, and overshoot endocytosis at large calyx-type synapses, and for slow endocytosis and bulk endocytosis at small hippocampal synapses.

  2. Splicing to include exon 3a is concomitant with previously described down-regulation of Actg1 in differentiating C2C12 cells

  3. These data support an essential role for beta-actin (show ACTB Proteins) in regulating cell migration and gene expression through control of the cellular G-actin (show ACTB Proteins) pool

  4. Results demonstrate overlapping developmental roles but unique post-developmental functions for beta-actin (show ACTB Proteins) and gamma-actin in maintaining hair cell stereocilia.

  5. Since the total amount of actin protein was maintained in Actg1(-/-) cells, our data suggests a distinct requirement for gamma(cyto)-actin in cell growth and survival.

  6. arginylated gamma-actin, unlike beta-, was highly unstable and selectively ubiquitinated and degraded in vivo; instability was regulated by differences in nucleotide coding sequence between the actin isoforms, which conferred different translation rates

  7. Eplin-alpha transcription is regulated by actin-MAL-SRF signalling.

  8. Organisation of non-muscle gamma-actin and co-localisation with sarcomeric alpha-actinin (show ACTN1 Proteins), a marker of sarcomere assembly and a major component of Z lines, was noted. Gamma-Actin was also found in young myotubes with developing sarcomeric myofibrils.

  9. Our data demonstrate an important role for minimally abundant but strategically localized gamma(cyto)-actin in adult skeletal muscle and describe a new mouse model to study the in vivo relevance of subcellular actin isoform sorting.

  10. G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers.

Actin, gamma 1 (ACTG1) Protein Profile

Protein Summary

Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Actin, gamma 1 (ACTG1)

  • actin, gamma 1 (ACTG1)
  • actin, gamma 1 (actg1-b)
  • actin, beta 2 (actb2)
  • actin, gamma 1 (Actg1)
  • Actin, gamma 1 (ACTG1)
  • actin, gamma 1 a (actg1)
  • actin, gamma, cytoplasmic 1 (Actg1)
  • ACT protein
  • actbb protein
  • Actg protein
  • actg1a protein
  • actg1b protein
  • actin protein
  • Actl protein
  • AL023024 protein
  • bact2 protein
  • bactin2 protein
  • BRWS2 protein
  • cytoplasmic protein
  • DFNA20 protein
  • DFNA26 protein
  • E51 protein
  • fa56g06 protein
  • fb38a10 protein
  • wu:fa56g06 protein
  • wu:fb38a10 protein

Protein level used designations for Actin, gamma 1 Proteins (ACTG1)

actin, cytoplasmic 2 , actin, gamma 1 , actin, cytoplasmic type 5 , actin, gamma 1 b , beta-actin-2 , actin, cytoplasmic 2-like , cytoskeletal gamma-actin , actin, gamma, cytoplasmic 1 , gamma-actin , actin, cytoplasmic, type 5 , actin, gamma 1 propeptide , cytoplasmic 2 , cytoplasmic type 5 , gamma 1 propeptide , type 5 , cytoplasmic actin , beta-actin , actin, cytoplasmic 2 a , beta-actin FE-3

746570 Pan troglodytes
100025924 Monodelphis domestica
100050139 Equus caballus
100337595 Xenopus laevis
57935 Danio rerio
100441387 Pongo abelii
100598167 Nomascus leucogenys
71 Homo sapiens
287876 Rattus norvegicus
415296 Gallus gallus
404122 Bos taurus
100731713 Cavia porcellus
442937 Canis lupus familiaris
100037088 Xenopus laevis
11465 Mus musculus
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