Browse our anti-AATF (AATF) Antibodies

Full name:
anti-Apoptosis Antagonizing Transcription Factor Antibodies (AATF)
On are 97 Apoptosis Antagonizing Transcription Factor (AATF) Antibodies from 22 different suppliers available. Additionally we are shipping AATF Kits (23) and AATF Proteins (15) and many more products for this protein. A total of 143 AATF products are currently listed.
4933415H02Rik, 5830465M17Rik, AATF, cb109, Che-1, CHE1, Ded, sb:cb109, Trb, wu:fc13d05, zgc:162071

Most Popular Reactivities for anti-AATF (AATF) Antibodies

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anti-Human AATF Antibodies:

anti-Mouse (Murine) AATF Antibodies:

anti-Rat (Rattus) AATF Antibodies:

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Top referenced anti-AATF Antibodies

  1. Human Monoclonal AATF Primary Antibody for IF, WB - ABIN393641 : Bruno, Desantis, Bossi, Di Agostino, Sorino, De Nicola, Iezzi, Franchitto, Benassi, Galanti, La Rosa, Floridi, Bellacosa, Passananti, Blandino, Fanciulli: Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation. in Cancer cell 2010 (PubMed)
    Show all 5 references for 393641

  2. Dog (Canine) Polyclonal AATF Primary Antibody for IHC, WB - ABIN2777467 : Burgdorf, Leister, Scheidtmann: TSG101 interacts with apoptosis-antagonizing transcription factor and enhances androgen receptor-mediated transcription by promoting its monoubiquitination. in The Journal of biological chemistry 2004 (PubMed)

  3. Human Polyclonal AATF Primary Antibody for ICC, IF - ABIN4277115 : Fagerberg, Stadler, Skogs, Hjelmare, Jonasson, Wiking, Abergh, Uhlén, Lundberg: Mapping the subcellular protein distribution in three human cell lines. in Journal of proteome research 2011 (PubMed)

  4. Human Polyclonal AATF Primary Antibody for IP, PLA - ABIN188634 : Moore, Bai, Boisvert, Latonen, Rantanen, Simpson, Pepperkok, Lamond, Laiho: Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation. in Molecular & cellular proteomics : MCP 2011 (PubMed)

  5. Cow (Bovine) Polyclonal AATF Primary Antibody for WB - ABIN2780860 : Lehner, Sanderson: A protein interaction framework for human mRNA degradation. in Genome research 2004 (PubMed)

More Antibodies against AATF Interaction Partners

Human Apoptosis Antagonizing Transcription Factor (AATF) interaction partners

  1. we identified the ANN complex as a novel functional module supporting the nucleolar maturation of 40S ribosomal subunits. Our data help to explain the described role of AATF in cell proliferation during mouse development as well as its requirement for malignant tumor growth.

  2. the effect of APOBEC3G (show APOBEC3G Antibodies) over-expression upon AATF gene expression, was examined.

  3. loss of Che-1 (show BCHE Antibodies) inhibits proliferation and promotes apoptosis in MG-63 cells by decreasing the level of mutant p53 (show TP53 Antibodies)

  4. It was concluded that PARP-1 (show PARP1 Antibodies) was involved in the DNA damage repair induced by HQ via increasing the accumulation of apoptosis antagonizing transcription factor through PARylation.

  5. These results confirm Che-1 as an important regulator of p53 activity and suggest Che-1 to be a promising yet attractive drug target for cancer therapy.

  6. In the face of high glucose threat, mitochondrial UCP2 (show UCP2 Antibodies) gene expression is regulated by miR (show MLXIP Antibodies)-2909 and AATF.

  7. This mutant AATF along with its interactome consisting of SP1 (show PSG1 Antibodies), DNMT3B (show DNMT3B Antibodies) and Par-4 (show PAWR Antibodies) ensures cancer cell DNA methylation (show HELLS Antibodies) required for down-regulation of tumor suppressor genes.

  8. HIPK2 depletion strongly decreases Che-1 ubiquitylation and degradation.

  9. Che-1 (show BCHE Antibodies) expression correlates with the progression of multiple myeloma and is required for cell growth and survival.Che-1 controls mTOR (show FRAP1 Antibodies) through the induction of Redd1 (show DDIT4 Antibodies) and Deptor (show DEPTOR Antibodies), two important repressors of mTOR (show FRAP1 Antibodies).

  10. Cell proliferation decreased by 41% which was accompanied by apoptosis induction in 30% MCF-7 cells after AATF gene knockdown.

Mouse (Murine) Apoptosis Antagonizing Transcription Factor (AATF) interaction partners

  1. we found that object recognition memory persistence at 7days was impaired in Che-1(+/-) heterozygous mice. This is the first evidence showing that Che-1 is involved in memory processes.

  2. These results identify AATF as a nucleolar-confined c-Jun (show JUN Antibodies) cofactor whose expression levels and spatial distribution determine the stress-induced activity of c-Jun (show JUN Antibodies) and the levels of c-Jun (show JUN Antibodies)-mediated apoptosis.

  3. AATF is an endogenous antagonist of Par-4 (show F2RL3 Antibodies) activity and an effective inhibitor of aberrant amyloid beta 1-42 production and secretion under apoptotic conditions.

  4. Che-1 as a new Pin1 (show PIN1 Antibodies) and HDM2 target and confirm its important role in the cellular response to DNA damage.

AATF Antigen Profile

Antigen Summary

The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.

Alternative names and synonyms associated with AATF

  • apoptosis antagonizing transcription factor (AATF) antibody
  • apoptosis antagonizing transcription factor (aatf) antibody
  • Apoptosis antagonizing transcription factor (BFR2) antibody
  • apoptosis antagonizing transcription factor (NAEGRDRAFT_56916) antibody
  • apoptosis antagonizing transcription factor (Aatf) antibody
  • 4933415H02Rik antibody
  • 5830465M17Rik antibody
  • AATF antibody
  • cb109 antibody
  • Che-1 antibody
  • CHE1 antibody
  • Ded antibody
  • sb:cb109 antibody
  • Trb antibody
  • wu:fc13d05 antibody
  • zgc:162071 antibody

Protein level used designations for AATF

apoptosis antagonizing transcription factor , protein AATF , Apoptosis antagonizing transcription factor , protein AATF-like , apoptosis-antagonizing transcription factor , rb-binding protein Che-1 , traube protein

100057601 Equus caballus
454601 Pan troglodytes
549062 Xenopus (Silurana) tropicalis
559477 Danio rerio
717586 Macaca mulatta
4852007 Scheffersomyces stipitis CBS 6054
8852758 Naegleria gruberi strain NEG-M
100404639 Callithrix jacchus
100451788 Pongo abelii
100580798 Nomascus leucogenys
26574 Homo sapiens
480595 Canis lupus familiaris
417653 Gallus gallus
786013 Bos taurus
56321 Mus musculus
114512 Rattus norvegicus
100381006 Xenopus laevis
100513881 Sus scrofa
100732839 Cavia porcellus
100356226 Oryctolagus cuniculus
101109984 Ovis aries
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