Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

AATF antibody (AA 1-39)

AATF Reactivity: Human, Mouse WB, IF Host: Rat Monoclonal 1B2D8 unconjugated
Catalog No. ABIN6971349
  • Target See all AATF Antibodies
    AATF (Apoptosis Antagonizing Transcription Factor (AATF))
    Binding Specificity
    • 9
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-39
    Reactivity
    • 45
    • 14
    • 11
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 44
    • 3
    Rat
    Clonality
    • 44
    • 3
    Monoclonal
    Conjugate
    • 34
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AATF antibody is un-conjugated
    Application
    • 34
    • 21
    • 12
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Characteristics
    AATF/Che-1, or Apoptosis-antagonizing Transcription Factoris a key regulator of apoptosis through its interaction with MAP3K12 (DLK), as well as regulation of gene transcription and cell profileration through interaction with RNA polymerase II. AATF/Che-1 may promote cell proliferation by acting as a competitor of histone deacetylase 1 (HDAC1) interaction with the growth inhibiting protein pRb. AATF / Che-1 binding to pRb may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. AATF / Che-1 antibody (mAb) (Clone 1B2D8) was raised in a Rat host. It has been validated for use in Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.
    Purification
    Protein A Chromatography
    Immunogen
    This antibody was raised against peptide comprising amino acids 1-39 of mouse AATF (Apoptosis-antagonizing transcription factor) (NP_062790).
    Clone
    1B2D8
    Isotype
    IgG2a
    Top Product
    Discover our top product AATF Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    AATF (Apoptosis Antagonizing Transcription Factor (AATF))
    Alternative Name
    AATF / Che-1 (AATF Products)
    NCBI Accession
    NP_062790
    Pathways
    Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
You are here:
Support