Browse our anti-RIT1 (RIT1) Antibodies

Full name:
anti-Ras-Like Without CAAX 1 Antibodies (RIT1)
On www.antibodies-online.com are 67 Ras-Like Without CAAX 1 (RIT1) Antibodies from 14 different suppliers available. Additionally we are shipping RIT1 Proteins (4) and RIT1 Kits (3) and many more products for this protein. A total of 83 RIT1 products are currently listed.
Synonyms:
MGC79097, NS8, RGD1559874, RIBB, Rit, rit1, ROC1, si:ch211-93a2.3
list all antibodies Gene Name GeneID UniProt
RIT1 499652  
RIT1 6016 Q92963
RIT1 19769 P70426

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Most Popular Reactivities for anti-RIT1 (RIT1) Antibodies

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anti-Rat (Rattus) RIT1 Antibodies:

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anti-Mouse (Murine) RIT1 Antibodies:

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Top referenced anti-RIT1 Antibodies

  1. Human Polyclonal RIT1 Primary Antibody for WB - ABIN265014 : Rusyn, Reynolds, Shao, Grana, Chan, Andres, Cox: Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways. in Oncogene 2000 (PubMed)

More Antibodies against RIT1 Interaction Partners

Pig (Porcine) Ras-Like Without CAAX 1 (RIT1) interaction partners

  1. swine UCHL3 (show Uchl3 Antibodies), RIT1 and CCND3 (show CCND3 Antibodies) genes were differentially expressed in tissues including small intestine, large intestine, liver, muscle, fat, lung, spleen and kidney

Human Ras-Like Without CAAX 1 (RIT1) interaction partners

  1. RIT1 is one of the major genes for NS. The RIT1-associated phenotype differs gradually from other NS subtypes, with a high prevalence of cardiovascular manifestations, especially hypertrophic cardiomyopathy.

  2. Congenital left main coronary artery atresia in a Noonan syndrome is associated with RIT1 variant, leading to unrescued sudden death.

  3. Noonan patients with germline RIT1 mutations are not at high risk to developing JMML or ALL, and that RIT1 has at most a marginal role in these sporadic malignancies.

  4. Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1).

  5. We report on a 2.5-year-old male patient with clinical signs of NS and hematologic abnormalities, in whom a novel heterozygous substitution in RIT1 with probable pathogenicity was detected.

  6. Mutations in RIT1 cause Noonan syndrome. Mutations in RIT1 affect RAS-MAPK (show MAPK1 Antibodies)/MEK (show MAP2K1 Antibodies)-ERK (show EPHB2 Antibodies) signaling. The mutant RIT1 protein may possess reduced GTPase (show RACGAP1 Antibodies) activity or a diminished ability to interact with cellular GTPase (show RACGAP1 Antibodies) activating proteins.

  7. elevated expression of RIT1 may contribute to the progression of endometrial cancer and thus may serve as a novel prognostic marker and a promising molecular target for the treatment of endometrial cancer.

  8. Because of the relatively high frequency of mutations in RIT1 among patients with NS and its occurrence in different populations, we suggest that it should be added to the list of genes included in panels for the molecular diagnosis of NS.

  9. A genotype-phenotype correlation analysis of available records indicated that germline RIT1 mutations cause a noonan syndrome phenotype characterized by a mild facial appearance.

  10. four additional cases of Noonan syndrome with mutations in RIT1, were identified.

Mouse (Murine) Ras-Like Without CAAX 1 (RIT1) interaction partners

  1. In adult hippocampal neuronal precursor cells, RIT1 controls an Akt (show AKT1 Antibodies)-dependent signaling cascade, resulting in the stabilization and transcriptional activation of phosphorylated Sox2 (show SOX2 Antibodies). This study supports a role for RIT1 in relaying niche-derived signals to neural/stem progenitor cells to control transcription of genes involved in self-renewal and differentiation

  2. the Rit-p38 (show CRK Antibodies)-MSK1 (show RPS6KA5 Antibodies)/2 signaling pathway may have an important role in the stress-dependent regulation of CREB (show CREB1 Antibodies)-dependent gene expression.

  3. these data identify a new and unexpected role for Rit in injury-induced neurogenesis, functioning as a selective survival mechanism for immature hippocampal neurons within the subgranular zone of the dentate gyrus following TBI.

  4. our studies establish the Rit GTPases as critical regulators of an evolutionarily conserved, p38 MAPK (show MAPK14 Antibodies)-dependent signaling cascade

  5. Rin (show RIT2 Antibodies) and Rit Bind to PAR6 (show PARD6A Antibodies) GTP (show AK3 Antibodies)-dependently and regulate cell transformation

RIT1 Antigen Profile

Antigen Summary

This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with RIT1

  • Ras-like without CAAX 1 (Rit1) antibody
  • Ras-like without CAAX 1 (RIT1) antibody
  • Ras-like without CAAX 1 (RCJMB04_9f23) antibody
  • Ras-like without CAAX 1 (rit1) antibody
  • Ras-like without CAAX 1 (LOC100342642) antibody
  • MGC79097 antibody
  • NS8 antibody
  • RGD1559874 antibody
  • RIBB antibody
  • Rit antibody
  • rit1 antibody
  • ROC1 antibody
  • si:ch211-93a2.3 antibody

Protein level used designations for RIT1

GTP-binding protein Rit1 , Ras-like without CAAX 1 , GTP-binding protein Roc1 , Ric-like, expressed in many tissues , ras-like protein expressed in many tissues , ras-like without CAAX protein 1 , RAS-like protein expressed in many tissues

GENE ID SPECIES
499652 Rattus norvegicus
480126 Canis lupus familiaris
533646 Bos taurus
100155905 Sus scrofa
425068 Gallus gallus
446484 Xenopus laevis
457377 Pan troglodytes
717985 Macaca mulatta
768118 Sus scrofa
793942 Danio rerio
100145877 Ovis aries
100342642 Oryctolagus cuniculus
6016 Homo sapiens
19769 Mus musculus
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