RIT1 antibody (AA 1-219)

Catalog No. ABIN7154596

Product Details anti-RIT1 Antibody

Target: RIT1 (Ras-Like Without CAAX 1 (RIT1))

Binding Specificity: AA 1-219

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIT1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human GTP-binding protein Rit1 protein (1-219AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RIT1

Target: RIT1 (Ras-Like Without CAAX 1 (RIT1))

Alternative Name: RIT1 (RIT1 Products)

Synonyms: NS8 antibody, RIBB antibody, RIT antibody, ROC1 antibody, RIT1 antibody, rit1 antibody, MGC79097 antibody, RGD1559874 antibody, si:ch211-93a2.3 antibody, Rit antibody, Ras like without CAAX 1 antibody, Ras-like without CAAX 1 L homeolog antibody, Ras-like without CAAX 1 antibody, RIT1 antibody, rit1.L antibody, Rit1 antibody, rit1 antibody

Background:

Background: Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.

Aliases: GTP binding protein Roc1 antibody, GTP-binding protein Rit1 antibody, NS8 antibody, Ras like protein expressed in many tissues antibody, Ras like without CAAX 1 antibody, Ras-like protein expressed in many tissues antibody, Ras-like without CAAX protein 1 antibody, RIBB antibody, Ric like expressed in many tissues antibody, Ric-like protein without CAAX motif 1 antibody, RIT antibody, RIT1 antibody, RIT1_HUMAN antibody, ROC1 antibody

UniProt: Q92963

Pathways: Neurotrophin Signaling Pathway