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Mouse (Murine) EGF Protein expressed in Yeast - ABIN2007864
Dreux, Lamb, Modjtahedi, Ferns: The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis. in Atherosclerosis 2006
Show all 5 references for ABIN2007864
Mouse (Murine) EGF Protein expressed in Escherichia coli (E. coli) - ABIN2666932
Henson, Gibson: Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: implications for cancer therapy. in Cellular signalling 2006
Show all 5 references for ABIN2666932
Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN2666930
Barnes: Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture. in The Journal of cell biology 1982
Show all 5 references for ABIN2666930
Rat (Rattus) EGF Protein expressed in Escherichia coli (E. coli) - ABIN2009632
Carpenter, Cohen: Epidermal growth factor. in The Journal of biological chemistry 1990
Show all 3 references for ABIN2009632
Mouse (Murine) EGF Protein expressed in Human Cells - ABIN2007863
Hommel, Harvey, Driscoll, Campbell: Human epidermal growth factor. High resolution solution structure and comparison with human transforming growth factor alpha. in Journal of molecular biology 1992
Show all 3 references for ABIN2007863
Dog (Canine) EGF Protein expressed in Escherichia coli (E. coli) - ABIN2008847
Goodsell: The molecular perspective: epidermal growth factor. in Stem cells (Dayton, Ohio) 2003
Show all 3 references for ABIN2008847
Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN2452188
Cohen, Carpenter: Human epidermal growth factor: isolation and chemical and biological properties. in Proceedings of the National Academy of Sciences of the United States of America 1975
Show all 2 references for ABIN2452188
Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN2215428
Zhou, Zhang, Jin, Chen, Wu, Li, Yue, Luo, Wang: Prokaryotic expression and refolding of EGFR extracellular domain and generation of phage display human scFv against EGFR. in Biomedicine & pharmacotherapy 2013
Zebrafish scube1 (show SCUBE1 Proteins) (signal peptide-CUB (complement protein C1r (show C1R Proteins)/C1s (show C1S Proteins), Uegf, and Bmp1 (show BMP1 Proteins))-EGF (epidermal growth factor) domain-containing protein 1) is involved in primitive hematopoiesis
EGF is likely a potential paracrine/juxtacrine factor from the oocytes to regulate the function of the follicle cells.
These results suggest that there is an EGF signaling network in the zebrafish ovarian follicle, and the functionality of this network is self-regulated by its own members.
Subgroup analysis in a Slovak population by gender showed the genotype EGF G61G and allele G was associated with non significantly increased risk of MDD.
EGF G1380A SNP was associated with the susceptibility and prognosis of malignant melanoma.
Therefore, EGF is suggested to induce E-cadherin (show CDH1 Proteins) down-regulation at the transcriptional level through the MEK (show MAP2K1 Proteins)/ERK (show EPHB2 Proteins) pathway, which might result in, at least in part, the induction of cellular morphological changes and cell migration in LoVo cells.
EGF and insulin receptor tyrosine kinase exemplify how receptor location is coupled to signal transduction. (Review)
These results indicate that Kindlin-1 (show FERMT1 Proteins) is essential in EGF-induced re-epithelialization in skin wound healing and provide additional rationale for the clinical application of EGF in the treatment of acute wounds.
angiopoietin-like 4 (show ANGPTL4 Proteins) plays an important role in the regulation of epidermal growth factor induced cancer metastasis
EGF/MCP-1 (show CCL2 Proteins) ratio is independently associated with severity of tubular atrophy and interstitial fibrosis in primary glomerulonephritis, but the ability of EGF/MCP-1 (show CCL2 Proteins) ratio to discriminate moderate to severe IFTA may not be much better than EGF alone.
SMOC binds to Pro-EGF, but does not induce Erk (show EPHB2 Proteins) phosphorylation via the EGFR (show EGFR Proteins).
findings indicate that the effects of stimulation with EGF, HGF (show HGF Proteins) and TGFbeta (show TGFB1 Proteins) on melanoma cell invasiveness could depend on melanoma cell progression stage.
Epidermal Growth Factor polymorphisms are associated with increased rate of sustained virological response.
concentration of EGF is critical for the switch between hair follicle growth and inhibition, and EGF promotes DP cell proliferation via Notch (show NOTCH1 Proteins) signaling pathway
EGF promotes FoxM1 (show FOXM1 Proteins) expression through the ERK (show EPHB2 Proteins) signal pathway
Data indicate that Sonic hedgehog (Shh (show SHH Proteins)) stimulate branching morphogenesis (BrM (show SMARCA2 Proteins)) and induced synthesis of mRNAs for Ptch1 (show PTCH1 Proteins) protein, epidermal growth factor (EGF) and receptors of the ErbB (show EGFR Proteins) receptors ErbB1 (show EGFR Proteins), ErbB2 (show ERBB2 Proteins) and ErbB3 (show ERBB3 Proteins).
Either LIF (show LIF Proteins) or EGF is needed during development of pre-implantation embryo.
PXR (show NR1I2 Proteins) activation stimulates EGF-mediated hepatocyte proliferation in mice, at least in part, through inhibiting FOXO3 (show FOXO3 Proteins) from accelerating cell-cycle progression.
Data (including data from studies in knockout mice) suggest that Epab (embryonic poly(A)-binding protein), which is oocyte specific, is required for ability of cumulus cells and granulosa cells to exhibit responsiveness to Egf/Egfr (show EGFR Proteins) signaling.
modulation of EGF signaling affects in vitro expansion and differentiation of progenitors from embryonic pancreas of both mice and man.
TLR4 (show TLR4 Proteins) blockade prevented TPN (show TAPBP Proteins)-associated intestinal mucosa atrophy by preserving proliferation and preventing apoptosis. This is driven by a reduction in TNF-alpha (show TNF Proteins) abundance and increased EGF.
EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 (show GATA4 Proteins) in a time- and dose-dependent manner.
Interval between litters and litter size may be linked with EGF polymorphisms in pigs.
10 nM/L EGF was the optimal dose for serum-free culture, which can replace traditional standard serum medium for in vitro expansion of miniature pig bone marrow-derived mesenchymal stem cells.
EGF coordinately activates multiple cell signaling pathways critical to proliferation, migration and survival of trophectoderm cells.
progesterone-induced TACE/ADAM17 (show ADAM17 Proteins) leads to production of soluble EGF domain from cumulus cells, which enhances functional changes of cumulus cells and progresses meiotic maturation of oocytes
The phase-related expression of EGF and EGFR (show EGFR Proteins) in the endothelium of the uterine artery and its branches suggest the modulatory effect of EGF and its receptor on the uterine artery and the region supplying these vessels.
EGF appears to sensitize epithelial cells to the detrimental effects of IFN-alpha (show IFNA Proteins) but also helps to restore barrier function in the healing phase.
analysis of EGF in dairy cows reveals increased EGF concentrations for 2-3 days between Days 2 and 5
Data suggest that EGF expression in endometrium varies by species and parity; in Japanese Black cows, EGF expression is consistently high, while in Holstein cows, EGF expression is down-regulated in postpartum period after second calving.
Data suggest that epidermal growth factor receptor (show EGFR Proteins) B [ErbB (show EGFR Proteins)] isoforms and their ligands (epidermal growth factor [EGF], amphiregulin (show AREG Proteins) [AREG (show AREG Proteins)], and neuregulin-1 (show NRG1 Proteins) [NRG1 (show NRG1 Proteins)]) are expressed in uteroplacental tissues in mid- and late-phases of pregnancy.
EGF plays a role during bovine placentation.
Data suggest that epidermal growth factor (EGF) and EGF receptors are important paracrine and/or autocrine regulators of spermatogenesis in bovine.
This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
epidermal growth factor (beta-urogastrone)
, pro-epidermal growth factor
, Pro-epidermal growth factor precursor (EGF)