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Mouse (Murine) EGF Protein expressed in Escherichia coli (E. coli) - ABIN2666932
Henson, Gibson: Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: implications for cancer therapy. in Cellular signalling 2006
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Mouse (Murine) EGF Protein expressed in Yeast - ABIN2007864
Dreux, Lamb, Modjtahedi, Ferns: The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis. in Atherosclerosis 2006
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Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN2666930
Barnes: Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture. in The Journal of cell biology 1982
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Rat (Rattus) EGF Protein expressed in Escherichia coli (E. coli) - ABIN2009632
Carpenter, Cohen: Epidermal growth factor. in The Journal of biological chemistry 1990
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Dog (Canine) EGF Protein expressed in Escherichia coli (E. coli) - ABIN2008847
Hommel, Harvey, Driscoll, Campbell: Human epidermal growth factor. High resolution solution structure and comparison with human transforming growth factor alpha. in Journal of molecular biology 1992
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Mouse (Murine) EGF Protein expressed in Human Cells - ABIN2007859
Goodsell: The molecular perspective: epidermal growth factor. in Stem cells (Dayton, Ohio) 2003
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Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN2452188
Cohen, Carpenter: Human epidermal growth factor: isolation and chemical and biological properties. in Proceedings of the National Academy of Sciences of the United States of America 1975
Show all 2 references for ABIN2452188
Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN593405
An, Gip, Kim, Wu, Park, McVaugh, Schaffer, Bertozzi, Lebrilla: Extensive determination of glycan heterogeneity reveals an unusual abundance of high mannose glycans in enriched plasma membranes of human embryonic stem cells. in Molecular & cellular proteomics : MCP 2012
Show all 2 references for ABIN593405
Human EGF Protein expressed in Escherichia coli (E. coli) - ABIN1047548
Bell, Fong, Stempien, Wormsted, Caput, Ku, Urdea, Rall, Sanchez-Pescador: Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization. in Nucleic acids research 1987
Zebrafish scube1 (show SCUBE1 Proteins) (signal peptide-CUB (complement protein C1r (show C1R Proteins)/C1s (show C1S Proteins), Uegf, and Bmp1 (show BMP1 Proteins))-EGF (epidermal growth factor) domain-containing protein 1) is involved in primitive hematopoiesis
EGF is likely a potential paracrine/juxtacrine factor from the oocytes to regulate the function of the follicle cells.
These results suggest that there is an EGF signaling network in the zebrafish ovarian follicle, and the functionality of this network is self-regulated by its own members.
Epidermal Growth Factor polymorphisms are associated with increased rate of sustained virological response.
Data show that CD133 overexpression resulted in decreased EGF and EGFR (show EGFR Proteins) expression, increased telomerase reverse transcriptase (TERT (show TERT Proteins)) expression, and increased Akt (show AKT1 Proteins) phosphorylation.
lP-EGF was internalized by an active and selective mechanism through EGFR (show EGFR Proteins) without receptor activation. Oxaliplatin LP-EGF decreased IC50 between 48 and 13% in cell EGFR (show EGFR Proteins)+.
This study showed that CTX (show CYP27A1 Proteins) III inhibitory effect on EGF-evoked invasion of MDA-MB-231 cells is mediated through suppressing EGF/EGFR (show EGFR Proteins) activation and EMT (show ITK Proteins) process.
the role of Epidermal Growth Factor (EGF) and Poly-L-Ornithine (PLO) and PDX1 (show PDX1 Proteins) on human amnion epithelial cell differentiation process, is reported.
CD24 (show CD24 Proteins) regulates EGFR (show EGFR Proteins) signaling by inhibiting EGFR (show EGFR Proteins) internalization and degradation in a RhoA (show RHOA Proteins)-dependent manner in gastric cancer cells.
EGF induces transient Ras activation and feedback phosphorylation of Sos.
This can be achieved by either blocking the EGF or CSF-1 (show CSF1 Proteins) receptors or supressing the EGF or CSF-1 (show CSF1 Proteins) signal.
This ubiquitin-mediated switch in EGFR (show EGFR Proteins) trafficking is a uniquely suited solution to suppress spontaneous activation while maintaining responsiveness to EGF.
endometrial- and/or conceptus derived EGF effects migration of uterine luminal epithelium.
concentration of EGF is critical for the switch between hair follicle growth and inhibition, and EGF promotes DP cell proliferation via Notch (show NOTCH1 Proteins) signaling pathway
EGF promotes FoxM1 (show FOXM1 Proteins) expression through the ERK (show EPHB2 Proteins) signal pathway
Data indicate that Sonic hedgehog (Shh (show SHH Proteins)) stimulate branching morphogenesis (BrM (show SMARCA2 Proteins)) and induced synthesis of mRNAs for Ptch1 (show PTCH1 Proteins) protein, epidermal growth factor (EGF) and receptors of the ErbB (show EGFR Proteins) receptors ErbB1 (show EGFR Proteins), ErbB2 (show ERBB2 Proteins) and ErbB3 (show ERBB3 Proteins).
Either LIF (show LIF Proteins) or EGF is needed during development of pre-implantation embryo.
PXR (show NR1I2 Proteins) activation stimulates EGF-mediated hepatocyte proliferation in mice, at least in part, through inhibiting FOXO3 (show FOXO3 Proteins) from accelerating cell-cycle progression.
Data (including data from studies in knockout mice) suggest that Epab (embryonic poly(A)-binding protein), which is oocyte specific, is required for ability of cumulus cells and granulosa cells to exhibit responsiveness to Egf/Egfr (show EGFR Proteins) signaling.
modulation of EGF signaling affects in vitro expansion and differentiation of progenitors from embryonic pancreas of both mice and man.
TLR4 (show TLR4 Proteins) blockade prevented TPN (show TAPBP Proteins)-associated intestinal mucosa atrophy by preserving proliferation and preventing apoptosis. This is driven by a reduction in TNF-alpha (show TNF Proteins) abundance and increased EGF.
EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 (show GATA4 Proteins) in a time- and dose-dependent manner.
These data demonstrate that Mcl-1 (show MCL1 Proteins) is essential for mammopoiesis and identify EGF as a critical trigger of Mcl-1 (show MCL1 Proteins) translation to ensure survival of milk-producing alveolar cells.
Interval between litters and litter size may be linked with EGF polymorphisms in pigs.
10 nM/L EGF was the optimal dose for serum-free culture, which can replace traditional standard serum medium for in vitro expansion of miniature pig bone marrow-derived mesenchymal stem cells.
EGF coordinately activates multiple cell signaling pathways critical to proliferation, migration and survival of trophectoderm cells.
progesterone-induced TACE/ADAM17 (show ADAM17 Proteins) leads to production of soluble EGF domain from cumulus cells, which enhances functional changes of cumulus cells and progresses meiotic maturation of oocytes
The phase-related expression of EGF and EGFR (show EGFR Proteins) in the endothelium of the uterine artery and its branches suggest the modulatory effect of EGF and its receptor on the uterine artery and the region supplying these vessels.
EGF appears to sensitize epithelial cells to the detrimental effects of IFN-alpha (show IFNA Proteins) but also helps to restore barrier function in the healing phase.
Data suggest that EGF expression in endometrium varies by species and parity; in Japanese Black cows, EGF expression is consistently high, while in Holstein cows, EGF expression is down-regulated in postpartum period after second calving.
Data suggest that epidermal growth factor receptor (show EGFR Proteins) B [ErbB (show EGFR Proteins)] isoforms and their ligands (epidermal growth factor [EGF], amphiregulin (show AREG Proteins) [AREG (show AREG Proteins)], and neuregulin-1 (show NRG1 Proteins) [NRG1 (show NRG1 Proteins)]) are expressed in uteroplacental tissues in mid- and late-phases of pregnancy.
EGF plays a role during bovine placentation.
Data suggest that epidermal growth factor (EGF) and EGF receptors are important paracrine and/or autocrine regulators of spermatogenesis in bovine.
This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
epidermal growth factor (beta-urogastrone)
, pro-epidermal growth factor
, Pro-epidermal growth factor precursor (EGF)