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Browse our anti-Insulin (INS) Antibodies

Full name:
anti-Insulin Antibodies (INS)
On www.antibodies-online.com are 1068 Insulin (INS) Antibodies from 37 different suppliers available. Additionally we are shipping Insulin Kits (199) and Insulin Proteins (49) and many more products for this protein. A total of 1326 Insulin products are currently listed.
Synonyms:
AA986540, IDDM2, ILPR, Ins-2, ins1, ins1-a, InsII, Insulin, IRDN, Mody, Mody4, MODY10, proinsulin, xins, zgc:109842

All available anti-Insulin Antibodies

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Top referenced anti-Insulin Antibodies

  1. Human Polyclonal Insulin Primary Antibody for EIA, FACS - ABIN372838 : Madsen, Knauf, Gotfredsen, Pilling, Sjögren, Andersen, Andersen, de Boer, Manova, Barlas, Vundavalli, Nyborg, Knudsen, Moelck, Fagin: GLP-1 receptor agonists and the thyroid: C-cell effects in mice are mediated via the GLP-1 receptor and not associated with RET activation. in Endocrinology 2012 (PubMed)
    Show all 2 references for ABIN372838

  2. Cow (Bovine) Monoclonal Insulin Primary Antibody for IHC (p) - ABIN112181 : Madsen: Proinsulin-specific monoclonal antibodies. Immunocytochemical application as beta-cell markers and as probes for conversion. in Diabetes 1987 (PubMed)
    Show all 2 references for ABIN112181

  3. Cow (Bovine) Monoclonal Insulin Primary Antibody for EIA, Func - ABIN111965 : Horejsí, Hilgert, Kristofová, Satayalai: Murine hybridoma monoclonal antibodies against insulin: cross-reactivity with insulins of three species and blocking of insulin binding to its receptor. in Immunology letters 1985 (PubMed)

  4. Human Monoclonal Insulin Primary Antibody for IHC (p) - ABIN616068 : Hilgert, Stolba, Kristofová, Stefanová, Bendlová, Lebl, Horejsí: A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA. in Hybridoma 1991 (PubMed)

  5. Human Monoclonal Insulin Primary Antibody for EIA, IHC (fro) - ABIN117970 : Hopkins, Williams: Insulin receptors are widely distributed in human brain and bind human and porcine insulin with equal affinity. in Diabetic medicine : a journal of the British Diabetic Association 1998 (PubMed)

  6. Human Monoclonal Insulin Primary Antibody for IHC (p), IP - ABIN1107760 : Harper, Ullrich, Saunders: Localization of the human insulin gene to the distal end of the short arm of chromosome 11. in Proceedings of the National Academy of Sciences of the United States of America 1981 (PubMed)

  7. Cow (Bovine) Monoclonal Insulin Primary Antibody for EIA, IHC (fro) - ABIN112214 : Qin, Jiao, Chen, Zhou, Liang, Zhong: Overexpression of suppressor of cytokine signaling 1 in islet grafts results in anti-apoptotic effects and prolongs graft survival. in Life sciences 2009 (PubMed)

More Antibodies against Insulin Interaction Partners

Human Insulin (INS) interaction partners

  1. Data indicate that the simulated model show that exocytosis as what occurs during insulin secretion.

  2. Our results revealed that the CRISPR-on system fused with transcriptional activators (dCas9-VP160) activated endogenous human INS, which is a silenced gene with a fully methylated promoter.

  3. Association between insulin gene VNTR and polycystic ovary syndrome (PCOS) was studied in Romanian women.

  4. The new INS mutation broadens the spectrum of possible INS phenotypes. Screening for INS mutations is warranted not only in neonatal diabetes but also in Maturity-Onset Diabetes of the Young patients and in selected patients with type 1 diabetes mellitus negative for autoantibodies

  5. The results of transmission electron microscopy, structural analyses, and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay show that the fibrils formed under conditions more closely resembling physiological conditions have different properties from the fibrils described to date. The novel insulin fibrils show strong cytotoxicity under physiological pH.

  6. A specific covalently linked dimeric species of insulin high molecular weight products (HMWPs), formed during prolonged incubation of a neutral pharmaceutical formulation of human insulin, were characterized in terms of tertiary structure, self-association, biological activity, and fibrillation properties. The dimer was formed by a covalent link between A21Asn and B29Lys.

  7. Taken together, these results demonstrate that insulin and TGF-beta3 (show TGFB3 Antibodies) present antagonistic effects during the chondrogenesis of human bone marrow-derived stem/progenitor cells.

  8. Sulfatide is known to stabilize insulin crystals, and we demonstrate here that in beta cells sulfatide is likely coating insulin crystals. However, there is no evidence for sulfatide to be built into the crystal lattice.

  9. The conserved tyrosine B26 contribute to the function and stability of human insulin.

  10. Insulin increases the expression of TRPC6 (show TRPC6 Antibodies) channels in podocytes by activation of the calcineurin (show PPP3CA Antibodies)-dependent pathway.

Pig (Porcine) Insulin (INS) interaction partners

  1. PTPLAD1 (show PTPLAD1 Antibodies) and AMPK (show PRKAA1 Antibodies) are rapidly compartmentalized within the plasma membrane (PM) and Golgi/endosome fractions after insulin stimulation and that ATIC (show ATIC Antibodies) later accumulates in the Golgi/endosome fraction.

  2. Pdx-1 (show PDX1 Antibodies), MafA (show MAFA Antibodies) and NeuroD1 (show NEUROD1 Antibodies) bind to the A, C and E elements in the insulin promoter and regulate the transcriptional activity of the insulin promoter.

  3. The interplay of the adiponectin (show ADIPOQ Antibodies) system, TNFalpha (show TNF Antibodies) and insulin at a transcriptional level and, their effects on the adipogenic transcription factor PPARgamma (show PPARG Antibodies), as well as on the activation of main insulin signaling pathways, is reported.

  4. Thermodynamics of insulin unfolding have been quantified by differential scanning calorimetry and thermal unfolding measurements to determine the extent and nature of their stabilization of the insulin hexamer.

  5. Exposing the hydrophobic core of insulin can induce the increase of amyloidogenicity and formation of higher-order polymerized fibrils, which is less toxic to membranes.

  6. Data suggest that a mutation in INS (C94Y) results a transgenic disease model for the investigation of permanent neonatal diabetes.

  7. The results show that modulation of plasma insulin levels by dietary carbohydrates seems possible in anabolic sows, but IGF-I (show IGF1 Antibodies) levels are less easily modified.

  8. insulin increased GCLc (show GCLC Antibodies) promoter activity, which required a prerequisite increase or decrease in medium glucose

  9. SOCS3 (show SOCS3 Antibodies) is an important negative regulator of insulin signaling in porcine adipocytes.

  10. Plasma concentrations of insulin in pigs fed once per day were lower before feeding than after the meal. Plasma concentrations of insulin in ad libitum fed pigs exhibited random fluctuations.

Cow (Bovine) Insulin (INS) interaction partners

  1. Insulin signaling role in skeletal muscle atrophy and autophagy in in transition and postpartum period

  2. Differences between human and bovine insulin kinetics under shear

  3. increased sensitivity to glucose clearance and skeletal muscle insulin signaling during dietary restriction

  4. Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin (show LEP Antibodies)-NPY (show NPY Antibodies) and insulin signaling pathways.

  5. Raman spectra of amino acids by Density Functional Theory method have been calculated. Experimental Raman spectra of insulin has been done. The simulated Raman spectrum of insulin is obtained from amino acid spectrum.

  6. Contains Binding kinetics for insulin binding

  7. Using synchrotron radiation (SR), the crystal structures of T6 bovine insulin complexed with Ni(2 (show VMP1 Antibodies)+) and Cu(2+) were solved to 1.50 and 1.45 A resolution, respectively.

  8. Thermodynamics of insulin unfolding have been quantified by differential scanning calorimetry and thermal unfolding measurements to determine the extent and nature of their stabilization of the insulin hexamer.

  9. The present study examined the effect of insulin-mediated activation of the mammalian target of rapamycin (show FRAP1 Antibodies) complex 1 (MTORC1) signaling network on the proliferation of primary culture of theca-interstitial (T-I) cells.

  10. In-situ spectroscopic investigation of ultrasonic assisted unfolding and aggregation of insulin.

Rabbit Insulin (INS) interaction partners

  1. insulin supports early initiation of the mesodermal factor Brachyury (show TBX1 Antibodies) and the signalling molecules Wnt3a (show WNT3A Antibodies) and Wnt4 (show WNT4 Antibodies) as well as the progression of mesoderm formation

  2. Data show that type 1 diabetic blastocyst did not express insulin mRNA.

Mouse (Murine) Insulin (INS) interaction partners

  1. Wnt3a increased the expression of NeuroD1 and Ins2 in the hypothalamus.

  2. Data suggest that resveratrol acts on differentiating preadipocytes by inhibiting insulin signaling, mitochondrial biogenesis, and lipogenesis.

  3. have characterized the distinctive sex-specific phenotypes exhibited by the ApoE(-/-):Ins2(+/Akita) mouse model and present evidence for the action of sex hormones on pancreatic beta-cell function

  4. Data indicate that Src homology-2 domain containing protein B (SHB) deficiency causes a chronic increase in beta-cell focal adhesion kinase (FAK) activity that perturbs the normal insulin secretory characteristics of beta-cells.

  5. Mouse Ins2 and Ins1 promoters were transiently activated in mouse fetal hepatocytes of embryonic days 13.5 and 16.5, respectively.

  6. Data indicate that insulin/incomplete Freund's adjuvant (IFA) does not prevent but induces diabetes in RIP-CD80GP transgenic mice.

  7. RORalpha is a transcriptional activator of insulin.

  8. Mice deficient in coinhibitory PD-L1 (show CD274 Antibodies) or PD-1 (show PDCD1 Antibodies) molecules (PD-L1 (show CD274 Antibodies)(-/-) and PD-1 (show PDCD1 Antibodies)(-/-) mice), were used to study induction of preproinsulin (ppins)-specific CD8 (show CD8A Antibodies) T-cell responses and experimental autoimmune diabetes.

  9. Data suggest that CD34 (show CD34 Antibodies) may be a specific marker for functionality, with some specificity for insulin.

  10. Akita mouse has a mutation in Ins2 and is a model of the effects of maternal and paternal hyperglycemia in wildtype offspring

Zebrafish Insulin (INS) interaction partners

  1. Temporal and spatial expression of two insulin genes (insa and insab) during early developmental stages.

  2. These findings suggest that GHRL (show GHRL Antibodies) regulates INS synthesis by mediating its action on growth hormone secretagogue-receptor (show GHSR Antibodies) in the central nervous system and partly involved in carbohydrate-glycogen (show GYS2 Antibodies) metabolism.

  3. Our results indicate that in adult tilapia insulin expression is not restricted to the endocrine pancreatic cells, but also occurs in endocrine cells of the pituitary gland and in the neuronal cells of the brain.

Insulin (INS) Antigen Profile

Antigen Summary

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Insulin (INS)

  • insulin (ins) antibody
  • insulin precursor (PIN) antibody
  • insulin (INS) antibody
  • insulin (Ins) antibody
  • insulin II (Ins2) antibody
  • insulin-like (LOC100060077) antibody
  • preproinsulin (ins) antibody
  • AA986540 antibody
  • IDDM2 antibody
  • ILPR antibody
  • Ins-2 antibody
  • ins1 antibody
  • ins1-a antibody
  • InsII antibody
  • Insulin antibody
  • IRDN antibody
  • Mody antibody
  • Mody4 antibody
  • MODY10 antibody
  • proinsulin antibody
  • xins antibody
  • zgc:109842 antibody

Protein level used designations for anti-Insulin (INS) Antibodies

insulin I , insulin , preproinsulin , proinsulin , insulin-2 , insa

GENE ID SPECIES
100101718 Xenopus (Silurana) tropicalis
100533403 Aplysia californica
3630 Homo sapiens
397415 Sus scrofa
280829 Bos taurus
100009181 Oryctolagus cuniculus
101684928 Mustela putorius furo
483665 Canis lupus familiaris
493804 Felis catus
100379579 Cavia porcellus
396145 Gallus gallus
101794427 Anas platyrhynchos
449570 Pan troglodytes
16334 Mus musculus
100060077 Equus caballus
30262 Danio rerio
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