Browse our anti-Insulin (INS) Antibodies

Full name:
anti-Insulin Antibodies (INS)
On www.antibodies-online.com are 1073 Insulin (INS) Antibodies from 37 different suppliers available. Additionally we are shipping Insulin Kits (219) and Insulin Proteins (47) and many more products for this protein. A total of 1348 Insulin products are currently listed.
Synonyms:
AA986540, IDDM2, ILPR, Ins-2, ins1, ins1-a, InsII, Insulin, IRDN, Mody, Mody4, MODY10, proinsulin, xins, zgc:109842

All available anti-Insulin Antibodies

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Top referenced anti-Insulin Antibodies

  1. Human Polyclonal Insulin Primary Antibody for EIA, FACS - ABIN372838 : Madsen, Knauf, Gotfredsen, Pilling, Sjögren, Andersen, Andersen, de Boer, Manova, Barlas, Vundavalli, Nyborg, Knudsen, Moelck, Fagin: GLP-1 receptor agonists and the thyroid: C-cell effects in mice are mediated via the GLP-1 receptor and not associated with RET activation. in Endocrinology 2012 (PubMed)
    Show all 2 references for 372838

  2. Cow (Bovine) Monoclonal Insulin Primary Antibody for IHC (p) - ABIN112181 : Madsen: Proinsulin-specific monoclonal antibodies. Immunocytochemical application as beta-cell markers and as probes for conversion. in Diabetes 1987 (PubMed)
    Show all 2 references for 112181

  3. Cow (Bovine) Monoclonal Insulin Primary Antibody for EIA, Func - ABIN111965 : Horejsí, Hilgert, Kristofová, Satayalai: Murine hybridoma monoclonal antibodies against insulin: cross-reactivity with insulins of three species and blocking of insulin binding to its receptor. in Immunology letters 1985 (PubMed)

  4. Human Monoclonal Insulin Primary Antibody for IHC (p) - ABIN616068 : Hilgert, Stolba, Kristofová, Stefanová, Bendlová, Lebl, Horejsí: A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA. in Hybridoma 1991 (PubMed)

  5. Human Monoclonal Insulin Primary Antibody for EIA, IHC (fro) - ABIN117970 : Hopkins, Williams: Insulin receptors are widely distributed in human brain and bind human and porcine insulin with equal affinity. in Diabetic medicine : a journal of the British Diabetic Association 1998 (PubMed)

  6. Human Monoclonal Insulin Primary Antibody for IHC (p), IP - ABIN1107760 : Harper, Ullrich, Saunders: Localization of the human insulin gene to the distal end of the short arm of chromosome 11. in Proceedings of the National Academy of Sciences of the United States of America 1981 (PubMed)

  7. Cow (Bovine) Monoclonal Insulin Primary Antibody for EIA, IHC (fro) - ABIN112214 : Qin, Jiao, Chen, Zhou, Liang, Zhong: Overexpression of suppressor of cytokine signaling 1 in islet grafts results in anti-apoptotic effects and prolongs graft survival. in Life sciences 2009 (PubMed)

More Antibodies against Insulin Interaction Partners

Human Insulin (INS) interaction partners

  1. In pancreas sections from autoantibody-positive (Ab+) donors, insulin area and beta-cell mass are maintained before type 1 diabetes onset and that production of proinsulin increases. The pancreatic proinsulin-to-insulin area ratio was also increased in these donors with prediabetes

  2. microRNA-7 can differentiate human induced pluripotent stem cells into functional isletlike cell clusters secreting insulin in a short time.

  3. describe an alternative open reading frame within human insulin mRNA encoding a highly immunogenic polypeptide that is targeted by T cells in Type 1 Diabetes (T1D) patients. Cytotoxic T cells directed against the N-terminal peptide of this nonconventional product are present in the circulation of T1D patients, and such CD8 (show CD8A Antibodies)(+) T cells are capable of killing human beta cells, and thereby may be diabetogenic.

  4. Insulin stimulation of Akt1 (show AKT1 Antibodies) and Akt2 (show AKT2 Antibodies) signaling in Cystic fibrosis (show S100A8 Antibodies) airway cells was diminished compared with that observed in airway cells expressing wild-type CFTR (show CFTR Antibodies).

  5. The activation mechanism of insulin, IF-I, and IGF-II upon binding to corresponding receptors using molecular dynamics simulations has been reported.

  6. These data implicate the insulin-FoxM1 (show FOXM1 Antibodies)/PLK1 (show PLK1 Antibodies)/CENP-A (show CENPA Antibodies) pathway-regulated mitotic cell-cycle progression as an essential component in the beta cell adaptation to delay and/or prevent progression to diabetes.

  7. The reproducibility of proinsulin:C-peptide ratio (PI:C) benefits from the automated simultaneous determination of both hormones. HOMA2-IR-corrected PI:C may serve as a minimally invasive alternative to the more tedious hyperglycemic clamp test

  8. Evening postprandial insulin and GIP (show GIP Antibodies) responses and insulin resistance declined by over 30% after three meals that limited daily carbohydrate intake to 30% compared to no such changes after three 60%-carbohydrate meals, an effect that was independent of pre-meal exercise.

  9. The study results were suggestive of a positive association between Gly972Arg of IRS1 (show IRS1 Antibodies) and PCOS in the south Indian population, while INS, IRS2 (show IRS2 Antibodies), PPAR-G (show ARF6 Antibodies) and CAPN10 (show CAPN10 Antibodies) failed to show any association with PCOS in our studied population.

  10. We found inverse independent correlations between metabolic clearance rate of insulin (MCRI) and hepatic lipase (show LIPC Antibodies) (P = 0.0004), insulin secretion (P = 0.0002), alanine aminotransferase (show ALT Antibodies) (P = 0.0045), total fat mass (P = 0.014), and diabetes (P = 0.03). MCRI and apolipoprotein A-I (show APOA1 Antibodies) exhibited a positive independent correlation (P = 0.035).

Pig (Porcine) Insulin (INS) interaction partners

  1. Study used well-tempered bias exchange metadynamics simulations to determine the equilibrium ensembles of an insulin molecule under amyloidogenic conditions of low pH and high temperature. The folded state of a single insulin molecule was shown to be the most stable, longest-lived state even under amyloidogenic conditions.

  2. The findings are consistent with previous studies that indicate a link between Na,K-ATPase (show ATP1A1 Antibodies) activity and SFK signaling.

  3. PTPLAD1 (show PTPLAD1 Antibodies) and AMPK (show PRKAA1 Antibodies) are rapidly compartmentalized within the plasma membrane (PM) and Golgi/endosome fractions after insulin stimulation and that ATIC (show ATIC Antibodies) later accumulates in the Golgi/endosome fraction.

  4. Pdx-1 (show PDX1 Antibodies), MafA (show MAFA Antibodies) and NeuroD1 (show NEUROD1 Antibodies) bind to the A, C and E elements in the insulin promoter and regulate the transcriptional activity of the insulin promoter.

  5. The interplay of the adiponectin (show ADIPOQ Antibodies) system, TNFalpha (show TNF Antibodies) and insulin at a transcriptional level and, their effects on the adipogenic transcription factor PPARgamma (show PPARG Antibodies), as well as on the activation of main insulin signaling pathways, is reported.

  6. Thermodynamics of insulin unfolding have been quantified by differential scanning calorimetry and thermal unfolding measurements to determine the extent and nature of their stabilization of the insulin hexamer.

  7. Exposing the hydrophobic core of insulin can induce the increase of amyloidogenicity and formation of higher-order polymerized fibrils, which is less toxic to membranes.

  8. Data suggest that a mutation in INS (C94Y) results a transgenic disease model for the investigation of permanent neonatal diabetes.

  9. The results show that modulation of plasma insulin levels by dietary carbohydrates seems possible in anabolic sows, but IGF-I (show IGF1 Antibodies) levels are less easily modified.

  10. insulin increased GCLc (show GCLC Antibodies) promoter activity, which required a prerequisite increase or decrease in medium glucose

Cow (Bovine) Insulin (INS) interaction partners

  1. Insulin signaling role in skeletal muscle atrophy and autophagy in in transition and postpartum period

  2. Differences between human and bovine insulin kinetics under shear

  3. increased sensitivity to glucose clearance and skeletal muscle insulin signaling during dietary restriction

  4. Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin (show LEP Antibodies)-NPY (show NPY Antibodies) and insulin signaling pathways.

  5. Raman spectra of amino acids by Density Functional Theory method have been calculated. Experimental Raman spectra of insulin has been done. The simulated Raman spectrum of insulin is obtained from amino acid spectrum.

  6. Contains Binding kinetics for insulin binding

  7. Using synchrotron radiation (SR), the crystal structures of T6 bovine insulin complexed with Ni(2 (show VMP1 Antibodies)+) and Cu(2+) were solved to 1.50 and 1.45 A resolution, respectively.

  8. Thermodynamics of insulin unfolding have been quantified by differential scanning calorimetry and thermal unfolding measurements to determine the extent and nature of their stabilization of the insulin hexamer.

  9. The present study examined the effect of insulin-mediated activation of the mammalian target of rapamycin (show FRAP1 Antibodies) complex 1 (MTORC1) signaling network on the proliferation of primary culture of theca-interstitial (T-I) cells.

  10. In-situ spectroscopic investigation of ultrasonic assisted unfolding and aggregation of insulin.

Rabbit Insulin (INS) interaction partners

  1. insulin supports early initiation of the mesodermal factor Brachyury (show TBX1 Antibodies) and the signalling molecules Wnt3a (show WNT3A Antibodies) and Wnt4 (show WNT4 Antibodies) as well as the progression of mesoderm formation

  2. Data show that type 1 diabetic blastocyst did not express insulin mRNA.

Mouse (Murine) Insulin (INS) interaction partners

  1. report that EndMTs occur in the diabetic endothelium of Ins2Akita/wt mouse, and show that induction of sex determining region Y-box 2 (Sox2 (show SOX2 Antibodies)) is a mediator of excess BMP signaling that results in activation of EndMTs and increased vascular calcification

  2. Transplantation of transduced hematopoietic stem cells (HSCs) expressing proinsulin II prevents diabetes development.

  3. Wnt3a increased the expression of NeuroD1 and Ins2 in the hypothalamus.

  4. Data suggest that resveratrol acts on differentiating preadipocytes by inhibiting insulin signaling, mitochondrial biogenesis, and lipogenesis.

  5. have characterized the distinctive sex-specific phenotypes exhibited by the ApoE(-/-):Ins2(+/Akita) mouse model and present evidence for the action of sex hormones on pancreatic beta-cell function

  6. Data indicate that Src homology-2 domain containing protein B (SHB) deficiency causes a chronic increase in beta-cell focal adhesion kinase (FAK) activity that perturbs the normal insulin secretory characteristics of beta-cells.

  7. Mouse Ins2 and Ins1 promoters were transiently activated in mouse fetal hepatocytes of embryonic days 13.5 and 16.5, respectively.

  8. Data indicate that insulin/incomplete Freund's adjuvant (IFA) does not prevent but induces diabetes in RIP-CD80GP transgenic mice.

  9. RORalpha is a transcriptional activator of insulin.

  10. Mice deficient in coinhibitory PD-L1 (show CD274 Antibodies) or PD-1 (show PDCD1 Antibodies) molecules (PD-L1 (show CD274 Antibodies)(-/-) and PD-1 (show PDCD1 Antibodies)(-/-) mice), were used to study induction of preproinsulin (ppins)-specific CD8 (show CD8A Antibodies) T-cell responses and experimental autoimmune diabetes.

Zebrafish Insulin (INS) interaction partners

  1. Temporal and spatial expression of two insulin genes (insa and insab) during early developmental stages.

  2. These findings suggest that GHRL (show GHRL Antibodies) regulates INS synthesis by mediating its action on growth hormone secretagogue-receptor (show GHSR Antibodies) in the central nervous system and partly involved in carbohydrate-glycogen (show GYS2 Antibodies) metabolism.

  3. Our results indicate that in adult tilapia insulin expression is not restricted to the endocrine pancreatic cells, but also occurs in endocrine cells of the pituitary gland and in the neuronal cells of the brain.

Insulin (INS) Antigen Profile

Antigen Summary

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Insulin (INS)

  • insulin (ins) antibody
  • insulin precursor (PIN) antibody
  • insulin (INS) antibody
  • insulin (Ins) antibody
  • insulin II (Ins2) antibody
  • insulin-like (LOC100060077) antibody
  • preproinsulin (ins) antibody
  • AA986540 antibody
  • IDDM2 antibody
  • ILPR antibody
  • Ins-2 antibody
  • ins1 antibody
  • ins1-a antibody
  • InsII antibody
  • Insulin antibody
  • IRDN antibody
  • Mody antibody
  • Mody4 antibody
  • MODY10 antibody
  • proinsulin antibody
  • xins antibody
  • zgc:109842 antibody

Protein level used designations for anti-Insulin (INS) Antibodies

insulin I , insulin , preproinsulin , proinsulin , insulin-2 , insa

GENE ID SPECIES
100101718 Xenopus (Silurana) tropicalis
100533403 Aplysia californica
3630 Homo sapiens
397415 Sus scrofa
280829 Bos taurus
100009181 Oryctolagus cuniculus
101684928 Mustela putorius furo
483665 Canis lupus familiaris
493804 Felis catus
100379579 Cavia porcellus
396145 Gallus gallus
101794427 Anas platyrhynchos
449570 Pan troglodytes
16334 Mus musculus
100060077 Equus caballus
30262 Danio rerio
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