Insulin antibody

Catalog No. ABIN6254161

This Goat Polyclonal antibody specifically detects Insulin in WB, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Mouse, Pig, Cow, Rat, Rabbit, Guinea Pig, Dog, Monkey, Cat, Chicken, Donkey, Goat, Hamster, Horse, Sheep and Avian.

Quick Overview for Insulin antibody (ABIN6254161)

Target: Insulin (INS)

Reactivity: Human, Mouse, Pig, Cow, Rat, Rabbit, Guinea Pig, Dog, Monkey, Cat, Chicken, Donkey, Goat, Hamster, Horse, Sheep, Avian

Host: Goat

Clonality: Polyclonal

Conjugate: This Insulin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Insulin Antibody

Purpose: Anti-INS

Sequence: MFVNQHLCGS HLVEALYLVC GERGFFYTPK TGIVEQCCTS ICSLYQLENY CN

Specificity: Gives a positive signal using MBP-Insulin recombinant fusion protein by WB.

Characteristics: Insulin

Purification: Epitope affinity purified

Immunogen: Purified recombinant human Insulin produced in E. coli as a fusion protein.

Isotype: IgG

Application Details

Application Notes: WB:1:250-1:2,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Restrictions: For Research Use only

Handling

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for Insulin

Target: Insulin (INS)

Alternative Name: INS

Background:

Goat polyclonal to Insulin. Insulin is a 6 kDa peptide, first synthesized as a precursor molecule, preproinsulin which is then processed into proinsulin and finally to the mature insulin. An increase in blood glucose levels during stimulates insulin release from pancreatic β cells. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake.

IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10 antibody.

Pathways: NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation