You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-IRAK4 (IRAK4) Antibodies

Full name:
anti-Interleukin-1 Receptor-Associated Kinase 4 Antibodies (IRAK4)
On www.antibodies-online.com are 193 Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Antibodies from 27 different suppliers available. Additionally we are shipping IRAK4 Proteins (11) and IRAK4 Kits (7) and many more products for this protein. A total of 221 IRAK4 products are currently listed.
Synonyms:
8430405M07Rik, 9330209D03Rik, IPD1, IRAK-4, irak4, ny-ran-64, NY-REN-64, REN64, zgc:55553
list all antibodies Gene Name GeneID UniProt
IRAK4 51135 Q9NWZ3
IRAK4 266632 Q8R4K2
IRAK4 300177  

Show all species

Show all synonyms

Most Popular Reactivities for anti-IRAK4 (IRAK4) Antibodies

Select your species and application

anti-Human IRAK4 Antibodies:

anti-Mouse (Murine) IRAK4 Antibodies:

anti-Rat (Rattus) IRAK4 Antibodies:

All available anti-IRAK4 Antibodies

Go to our pre-filtered search.

Top referenced anti-IRAK4 Antibodies

  1. Human Polyclonal IRAK4 Primary Antibody for EIA, IHC (p) - ABIN401362 : Branlant, Krol, Ebel: Characterization of the Escherichia coli 23S Ribosomal RNA region associated with ribosomal protein L1. Evidence for homologies with the 5'-end region of the L11 operon. in Nucleic acids research 1981 (PubMed)
    Show all 7 references for ABIN401362

  2. Human Polyclonal IRAK4 Primary Antibody for EIA, WB - ABIN952943 : McDonald, Goldman, Gomez-Duarte, Issekutz, Kumararatne, Doffinger, Geha: Impaired T-cell receptor activation in IL-1 receptor-associated kinase-4-deficient patients. in The Journal of allergy and clinical immunology 2010 (PubMed)
    Show all 5 references for ABIN952943

  3. Human Polyclonal IRAK4 Primary Antibody for EIA, IF - ABIN500044 : Cao, Henzel, Gao: IRAK: a kinase associated with the interleukin-1 receptor. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 2 references for ABIN500044

  4. Human Polyclonal IRAK4 Primary Antibody for WB - ABIN656802 : Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: Dengue hemorrhagic fever is associated with polymorphisms in JAK1. in European journal of human genetics : EJHG 2010 (PubMed)
    Show all 2 references for ABIN656802

  5. Human Monoclonal IRAK4 Primary Antibody for FACS, IHC - ABIN969218 : Pathak, De Souza, Salte, Wiker, Asjö: HIV induces both a down-regulation of IRAK-4 that impairs TLR signalling and an up-regulation of the antibiotic peptide dermcidin in monocytic cells. in Scandinavian journal of immunology 2009 (PubMed)
    Show all 2 references for ABIN969218

  6. Human Polyclonal IRAK4 Primary Antibody for WB - ABIN658069 : Erdman, Cosio, Helmers, Gowda, Grinstein, Kain: CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
    Show all 2 references for ABIN658069

  7. Human Polyclonal IRAK4 Primary Antibody for ELISA, WB - ABIN185338 : Lye, Mirtsos, Suzuki, Suzuki, Yeh: The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against IRAK4 Interaction Partners

Human Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) interaction partners

  1. This is the first study to show an association between single nucleotide polymorphisms in IRAK1 (show IRAK1 Antibodies), IRAK4 and MyD88 (show MYD88 Antibodies), and the presence of severe invasive pneumococcal disease.

  2. Src (show SRC Antibodies), Syk (show SYK Antibodies), IRAK1 (show IRAK1 Antibodies), and IRAK4 have roles in anti-inflammatory responses mediated by dietary flavonoid Kaempferol

  3. findings suggest that rare, functional variants in MYD88, IRAK4 or IKBKG do not significantly contribute to IPD susceptibility in adults at the population level

  4. High mRNA levels of IRAK1 (show IRAK1 Antibodies) and IRAK4 correlated with VKH disease activity.

  5. Studies indicate that interleukin-1 receptor-associated kinase 4 protein (IRAK4), a serine/threonine kinase, plays a key role in both inflammation and oncology diseases.

  6. by bolstering the IgM(+)IgD(+)CD27(+) B-cell subset, IRAK-4 and MyD88 promote optimal T-independent IgM antibody responses against bacteria in humans.

  7. delineation of the latter responses identified a narrow repertoire of transcriptional programs affected by loss of MyD88 (show MYD88 Antibodies) function or IRAK4 function

  8. Data show that dimerization is crucial for IRAK4 autophosphorylation in vitro and ligand dependent signaling in cells.

  9. these studies suggest that not only the loss of protein expression but also the defect of Myddosome formation couldcause IRAK4 and MyD88 (show MYD88 Antibodies) deficiency syndromes.

  10. IRAK4 is regulated by Interleukin 1/Toll (show TLR4 Antibodies)-like receptor-induced autophosphorylation

Mouse (Murine) Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) interaction partners

  1. PMA treatment during a vulnerable period can alter brain development. IL-18 and IRAK-4 appear to be important for the development of PMA induced injury.

  2. enforced expression of miR (show MLXIP Antibodies)-302b or IRAK4 siRNA silencing inhibits downstream NF-kappaB (show NFKB1 Antibodies) signalling and airway leukocyte infiltration, thereby alleviating lung injury and increasing survival in P. aeruginosa-infected mice.

  3. Our results demonstrate that osteoclasts and FBGCs are reciprocally regulated and identify IRAK4 as a potential therapeutic target to inhibit stimulated osteoclastogenesis and rescue inhibited FBGC formation

  4. Suggest FC-99 is a potential therapeutic molecule that alleviated experimental sepsis by directly inhibiting IRAK4 activation.

  5. MiR (show MLXIP Antibodies)-93 inhibits IRAK4 expression by binding directly to the 3'-UTR (show UTS2R Antibodies) of IRAK4.

  6. Intact IRAK4 function inhibited heart-specific migration of bone-marrow-derived CCR5 (show CCR5 Antibodies)(+) cells.

  7. In macrophages from IRAK4(KDKI) mice, IRAK4 kinase deficiency decreased LPS (show TLR4 Antibodies) signaling but did not prevent endotoxin tolerance. A TLR2 (show TLR2 Antibodies)-TLR1 (show TLR1 Antibodies) agonist attenuated TLR2 (show TLR2 Antibodies)-elicited homo- & heterotolerance at the level of MAPK (show MAPK1 Antibodies) activation.

  8. During bacterial infection, PGN (show SPG7 Antibodies)-mediated TLR2 (show TLR2 Antibodies) signaling induces miR (show MLXIP Antibodies)-132/-212 to downregulate IRAK4.

  9. IRAK4-deficient mice exhibit increased susceptibility and decreased cytokine production in vivo upon Streptococcus pneumoniae infection.

  10. Experimental and natural infections in MyD88 (show MYD88 Antibodies)- and IRAK-4-deficient mice and humans.

IRAK4 Antigen Profile

Antigen Summary

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with IRAK4

  • interleukin-1 receptor-associated kinase 4 (IRAK4) antibody
  • interleukin-1 receptor-associated kinase 4 (irak4) antibody
  • Interleukin-1 receptor-associated kinase 4 (irak4) antibody
  • interleukin-1 receptor-associated kinase 4 (LOC100227974) antibody
  • interleukin-1 receptor-associated kinase 4 (Irak4) antibody
  • 8430405M07Rik antibody
  • 9330209D03Rik antibody
  • IPD1 antibody
  • IRAK-4 antibody
  • irak4 antibody
  • ny-ran-64 antibody
  • NY-REN-64 antibody
  • REN64 antibody
  • zgc:55553 antibody

Protein level used designations for IRAK4

interleukin-1 receptor-associated kinase 4 , interleukin-1 receptor-associated kinase 4-like , Interleukin-1 receptor-associated kinase 4 , renal carcinoma antigen NY-REN-64 , NY-REN-64 antigen , interleukin-1 receptor associated kinase 4

GENE ID SPECIES
100054848 Equus caballus
100216438 Ovis aries
100019202 Monodelphis domestica
100447243 Pongo abelii
100469127 Ailuropoda melanoleuca
100528915 Ictalurus punctatus
393132 Danio rerio
417796 Gallus gallus
700568 Macaca mulatta
733738 Xenopus (Silurana) tropicalis
100196744 Salmo salar
100227974 Taeniopygia guttata
100402978 Callithrix jacchus
100602648 Nomascus leucogenys
51135 Homo sapiens
266632 Mus musculus
466962 Pan troglodytes
486601 Canis lupus familiaris
100127166 Sus scrofa
533692 Bos taurus
300177 Rattus norvegicus
100341605 Oryctolagus cuniculus
Selected quality suppliers for anti-IRAK4 (IRAK4) Antibodies
Did you look for something else?