Browse our anti-DLL4 (DLL4) Antibodies

Full name:
anti-delta-Like 4 Antibodies (DLL4)
On are 170 delta-Like 4 (DLL4) Antibodies from 24 different suppliers available. Additionally we are shipping DLL4 Proteins (28) and DLL4 Kits (24) and many more products for this protein. A total of 232 DLL4 products are currently listed.
Delta4, hdelta2, si:ch211-244p18.5, zgc:136596
list all antibodies Gene Name GeneID UniProt
DLL4 54567 Q9NR61
DLL4 54485 Q9JI71
DLL4 311332  

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Most Popular Reactivities for anti-DLL4 (DLL4) Antibodies

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anti-Human DLL4 Antibodies:

anti-Mouse (Murine) DLL4 Antibodies:

anti-Rat (Rattus) DLL4 Antibodies:

All available anti-DLL4 Antibodies

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Top referenced anti-DLL4 Antibodies

  1. Human Polyclonal DLL4 Primary Antibody for ELISA, IHC - ABIN269907 : Lauret, Catelain, Titeux, Poirault, Dando, Dorsch, Villeval, Groseil, Vainchenker, Sainteny, Bennaceur-Griscelli: Membrane-bound delta-4 notch ligand reduces the proliferative activity of primitive human hematopoietic CD34+CD38low cells while maintaining their LTC-IC potential. in Leukemia 2004 (PubMed)
    Show all 13 references for 269907

  2. Human Monoclonal DLL4 Primary Antibody for EIA, WB - ABIN1106965 : Sheldon, Heikamp, Turley, Dragovic, Thomas, Oon, Leek, Edelmann, Kessler, Sainson, Sargent, Li, Harris: New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. in Blood 2010 (PubMed)
    Show all 2 references for 1106965

  3. Human Polyclonal DLL4 Primary Antibody for EIA, IHC (p) - ABIN318838 : Thurston, Noguera-Troise, Yancopoulos: The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth. in Nature reviews. Cancer 2007 (PubMed)
    Show all 2 references for 318838

  4. Human Monoclonal DLL4 Primary Antibody for FACS, ELISA - ABIN969514 : Al Haj Zen, Oikawa, Bazan-Peregrino, Meloni, Emanueli, Madeddu: Inhibition of delta-like-4-mediated signaling impairs reparative angiogenesis after ischemia. in Circulation research 2010 (PubMed)
    Show all 2 references for 969514

  5. Human Monoclonal DLL4 Primary Antibody for IHC, ELISA - ABIN969515 : Jubb, Soilleux, Turley, Steers, Parker, Low, Blades, Li, Allen, Leek, Noguera-Troise, Gatter, Thurston, Harris: Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer. in The American journal of pathology 2010 (PubMed)
    Show all 2 references for 969515

  6. Human Polyclonal DLL4 Primary Antibody for IHC, ELISA - ABIN1043880 : Indraccolo, Minuzzo, Masiero, Pusceddu, Persano, Moserle, Reboldi, Favaro, Mecarozzi, Di Mario, Screpanti, Ponzoni, Doglioni, Amadori: Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy. in Cancer research 2009 (PubMed)
    Show all 2 references for 1043880

  7. Human Polyclonal DLL4 Primary Antibody for IHC, ELISA - ABIN129625 : Zhang, Zeng, Zhang, Jiao, Li, Jing, Ouyang, Yuan, Chai, Che, Zhang, Yang: Suppressor of cytokine signaling 3 promotes bone marrow cells to differentiate into CD8+ T lymphocytes in lung tissue via up-regulating Notch1 expression. in Cancer research 2009 (PubMed)
    Show all 2 references for 129625

  8. Cow (Bovine) Polyclonal DLL4 Primary Antibody for WB - ABIN2783745 : Williams, Segarra, Sierra, Sainson, Tosato, Harris: Regulation of CXCR4 by the Notch ligand delta-like 4 in endothelial cells. in Cancer research 2008 (PubMed)

More Antibodies against DLL4 Interaction Partners

Human delta-Like 4 (DLL4) interaction partners

  1. The authors present novel structures of human ligands Jagged2 (show JAG2 Antibodies) and Delta-like4 and human Notch2 (show NOTCH2 Antibodies), together with functional assays, which suggest that ligand-mediated coupling of membrane recognition and Notch (show NOTCH1 Antibodies) binding is likely to be critical in establishing the optimal context for Notch (show NOTCH1 Antibodies) signalling.

  2. Overexpression of DLL4 could significantly attenuate the cytotoxic effects of docetaxel in MCF-7 cells by increasing Bcl-2 (show BCL2 Antibodies) expression, while decreasing Bax (show BAX Antibodies) expression, apoptosis rate and DNA damage

  3. In gastric epithelial cells co-cultured with Helicobacter pylori, the expression level of the ligand DLL4 was found to be significantly increased.

  4. Low DLL4 abundance in tumour cells may predict the benefit from adjuvant gemcitabine therapy after PDAC resection.

  5. Angiogenesis in Infantile haemangioma (IH) appears to be controlled by DLL4 within the endothelium in a VEGF-A (show VEGFA Antibodies) isoform-dependent manner, and in perivascular cells in a VEGF (show VEGFA Antibodies)-independent manner. The contribution of VEGF-A (show VEGFA Antibodies) isoforms to disease progression also indicates that IH may be associated with altered splicing.

  6. Dll4 modulates liver inflammatory response by down-regulating chemokine (show CCL1 Antibodies) expression

  7. Positive Jagged1 (show JAG1 Antibodies) and DLL4 expression is closely correlated with severe clinicopathological characteristics and poor prognosis in patients with pancreatic ductal carcinoma.

  8. Data show that the IgA/delta-like protein 4 (Delta-4)/Notch (show NOTCH1 Antibodies) receptor (Notch (show NOTCH1 Antibodies)) axis is not observed in IgG-dendritic cells (DCs).

  9. Data suggest that the vascular DLL4-Notch4 signaling and VEGF signaling complementing each other plays an important role in the progression of tumor angiogenesis in primary glioblastoma.

  10. our data indicate that high DLL4 expression predicts pelvic lymph node metastasis and poor survival in cervical cancer. Therefore, DLL4 may be a potential clinical diagnostic marker for patients with early-stage cervical cancer.

Mouse (Murine) delta-Like 4 (DLL4) interaction partners

  1. Dll4-Notch1 (show NOTCH1 Antibodies) signalling couples sprouting angiogenesis and artery formation.

  2. Results suggest that Dll4 activation during differentiation sustained Treg cell phenotype and function to control respiratory syncytial virus infection.

  3. DLL4 expression is not associated with the Pathogenesis of Non-Alcoholic Steatohepatitis.

  4. The results demonstrate that the Vegf (show VEGFA Antibodies)-Dll4/Notch (show NOTCH1 Antibodies) feedback system normally operates to generate heterogeneity between endothelial cells driving blood vessel branching, whilst synchronization drives vessel expansion.

  5. Dll4 modulates liver inflammatory response by down-regulating chemokine (show CCL1 Antibodies) expression

  6. Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 (show NOTCH1 Antibodies) Signaling

  7. miRNA-30e targeted the 3'-UTR (show UTS2R Antibodies) of Dll4 and downregulated Dll4 expression

  8. Dll4/Notch (show NOTCH1 Antibodies) signaling and HIF-1alpha (show HIF1A Antibodies) are closely related to lymphangiogenesis in dry eye-induced lacrimal glands.

  9. Dll4-induced Notch1 (show NOTCH1 Antibodies) activity is required to specify the arterial programme in the aorta-gonad-mesonephros embryonic region.

  10. Tumor promoting effect of low-dosage inhibition needs to be considered when implementing Delta-like (show DLK1 Antibodies) 4 targeting therapies.

Zebrafish delta-Like 4 (DLL4) interaction partners

  1. Thsd7a (show THSD7A Antibodies) could regulate ISV angiogenesis via Notch (show NOTCH1 Antibodies)-dll4 signaling. Thus, Thsd7a (show THSD7A Antibodies) is a potent angioneurin involved in the development of both neural and vascular systems.

  2. show that blood flow suppresses vascular Notch (show NOTCH1 Antibodies) signalling via down-regulation of dll4

  3. Microinjection of miR (show MYLIP Antibodies)-30 mimics into zebrafish embryos resulted in suppression of dll4 and subsequent excessive sprouting of intersegmental vessels and reduction in dorsal aorta diameter.

  4. Notch (show NOTCH1 Antibodies) signalling pathway mutants Ectopic filopodia were also observed on the inter-somitic vessels of Notch (show NOTCH1 Antibodies) signalling pathway mutants. Ectopic filopodia are not due to loss of dll4.

  5. These studies imply critical roles for Dll4/Notch (show NOTCH1 Antibodies) signaling in the formation and wiring of the lymphatic network.

  6. Dll4-Notch signalling acts as an angiogenic ;off' switch by making endothelial cells unresponsive to Vegf.

  7. Vegfc (show VEGFC Antibodies)/Flt4 (show FLT4 Antibodies) signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries.

DLL4 Antigen Profile

Antigen Summary

This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.

Alternative names and synonyms associated with DLL4

  • delta-like 4 (Drosophila) (DLL4) antibody
  • delta-like 4 (Drosophila) (Dll4) antibody
  • delta-like 4 (Drosophila) (dll4) antibody
  • Delta4 antibody
  • hdelta2 antibody
  • si:ch211-244p18.5 antibody
  • zgc:136596 antibody

Protein level used designations for anti-delta-Like 4 (DLL4) Antibodies

delta-like protein 4 , delta 4 , delta ligand 4 , delta-like 4 homolog , delta-like 4 protein , delta4 , drosophila Delta homolog 4 , notch ligand DLL4 , notch ligand delta-2

100057073 Equus caballus
100152163 Sus scrofa
54567 Homo sapiens
54485 Mus musculus
311332 Rattus norvegicus
453344 Pan troglodytes
607575 Canis lupus familiaris
518746 Bos taurus
563920 Danio rerio
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