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Browse our anti-DLL4 (DLL4) Antibodies

Full name:
anti-delta-Like 4 Antibodies (DLL4)
On www.antibodies-online.com are 141 delta-Like 4 (DLL4) Antibodies from 20 different suppliers available. Additionally we are shipping DLL4 Proteins (22) and DLL4 Kits (15) and many more products for this protein. A total of 189 DLL4 products are currently listed.
Synonyms:
Delta4, hdelta2, si:ch211-244p18.5, zgc:136596
list all antibodies Gene Name GeneID UniProt
DLL4 54567 Q9NR61
DLL4 54485 Q9JI71
DLL4 311332  

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Most Popular Reactivities for anti-DLL4 (DLL4) Antibodies

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anti-Human DLL4 Antibodies:

anti-Mouse (Murine) DLL4 Antibodies:

anti-Rat (Rattus) DLL4 Antibodies:

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Top referenced anti-DLL4 Antibodies

  1. Chimpanzee Polyclonal DLL4 Primary Antibody for EIA, IHC (p) - ABIN401283 : Dorsch, Zheng, Yowe, Rao, Wang, Shen, Murphy, Xiong, Shi, Gutierrez-Ramos, Fraser, Villeval: Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease. in Blood 2002 (PubMed)
    Show all 5 references for ABIN401283

  2. Human Monoclonal DLL4 Primary Antibody for FACS, ELISA - ABIN969514 : Al Haj Zen, Oikawa, Bazan-Peregrino, Meloni, Emanueli, Madeddu: Inhibition of delta-like-4-mediated signaling impairs reparative angiogenesis after ischemia. in Circulation research 2010 (PubMed)
    Show all 2 references for ABIN969514

  3. Human Polyclonal DLL4 Primary Antibody for EIA, IHC (p) - ABIN318838 : Thurston, Noguera-Troise, Yancopoulos: The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth. in Nature reviews. Cancer 2007 (PubMed)
    Show all 2 references for ABIN318838

  4. Human Monoclonal DLL4 Primary Antibody for EIA, WB - ABIN1106965 : Sheldon, Heikamp, Turley, Dragovic, Thomas, Oon, Leek, Edelmann, Kessler, Sainson, Sargent, Li, Harris: New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. in Blood 2010 (PubMed)
    Show all 2 references for ABIN1106965

  5. Human Monoclonal DLL4 Primary Antibody for IHC, ELISA - ABIN969515 : Jubb, Soilleux, Turley, Steers, Parker, Low, Blades, Li, Allen, Leek, Noguera-Troise, Gatter, Thurston, Harris: Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer. in The American journal of pathology 2010 (PubMed)
    Show all 2 references for ABIN969515

  6. Human Polyclonal DLL4 Primary Antibody for IHC, ELISA - ABIN1043880 : Lauret, Catelain, Titeux, Poirault, Dando, Dorsch, Villeval, Groseil, Vainchenker, Sainteny, Bennaceur-Griscelli: Membrane-bound delta-4 notch ligand reduces the proliferative activity of primitive human hematopoietic CD34+CD38low cells while maintaining their LTC-IC potential. in Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004 (PubMed)
    Show all 2 references for ABIN1043880

  7. Human Polyclonal DLL4 Primary Antibody for IHC, ELISA - ABIN129625 : Zhang, Zeng, Zhang, Jiao, Li, Jing, Ouyang, Yuan, Chai, Che, Zhang, Yang: Suppressor of cytokine signaling 3 promotes bone marrow cells to differentiate into CD8+ T lymphocytes in lung tissue via up-regulating Notch1 expression. in Cancer research 2009 (PubMed)
    Show all 2 references for ABIN129625

  8. Cow (Bovine) Polyclonal DLL4 Primary Antibody for WB - ABIN2783745 : Williams, Segarra, Sierra, Sainson, Tosato, Harris: Regulation of CXCR4 by the Notch ligand delta-like 4 in endothelial cells. in Cancer research 2008 (PubMed)

  9. Mouse (Murine) Monoclonal DLL4 Primary Antibody for ICC, FACS - ABIN1169261 : Fiorini, Ferrero, Merck, Favre, Pierres, Luther, MacDonald: Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

More Antibodies against DLL4 Interaction Partners

Human delta-Like 4 (DLL4) interaction partners

  1. DLL4 and JAG1 (show JAG1 Antibodies) may have opposing effects on tumor angiogenesis in glioblastoma.

  2. Data indicate the role for altered forkhead box C2 (FoxC2)-Delta-like (show DLK1 Antibodies) ligand 4 (Dll4)signaling in structural alterations of saphenous veins in patients with varicose veins.

  3. Antagonism of the DLL4-Notch (show NOTCH1 Antibodies) signaling pathway might provide a potential therapeutic approach for breast cancer treatment by preventing angiogenesis.

  4. Activation of Dll4/Notch (show NOTCH1 Antibodies) signaling led to increased expression of ephrin-B2 (show EFNB2 Antibodies) and subsequent inhibition of endothelial progenitor cells activity.

  5. DLL4 is a unique functional molecule of human circulating dendritic cells critical for directing Th1 (show TH1L Antibodies) and Th17 differentiation

  6. The expression of DLL4 was positively correlated with CD105-labeled MVD (show MVD Antibodies).

  7. The detection of Notch1 (show NOTCH1 Antibodies) and Delta-like (show DLK1 Antibodies) 4 expression in peripheral blood lymphocytes of renal transplant recipients can serve as a positive indicator for evaluating the diagnosis and treatment efficacy of the AR reaction.

  8. Among all the Notch (show NOTCH1 Antibodies) ligands, Delta-like4 (Dll4) is specifically involved in angiogenesis. hD4R could suppress angiogenesis in vitro as manifested by network formation assay and sprouting assay.

  9. DLL4 and VEGFA (show VEGFA Antibodies) expression was closely related to tumour diameter, clinical stage, histological grade and lymph node metastasis.

  10. DLL4/Notch1 (show NOTCH1 Antibodies) and BMP9 (show GDF2 Antibodies) interdependent signaling induces endothelial cell quiescence via P27KIP1 (show CDKN1B Antibodies)/thrombospondin pathway.

Mouse (Murine) delta-Like 4 (DLL4) interaction partners

  1. miRNA-30e targeted the 3'-UTR (show UTS2R Antibodies) of Dll4 and downregulated Dll4 expression

  2. Dll4/Notch (show NOTCH1 Antibodies) signaling and HIF-1alpha (show HIF1A Antibodies) are closely related to lymphangiogenesis in dry eye-induced lacrimal glands.

  3. Dll4-induced Notch1 (show NOTCH1 Antibodies) activity is required to specify the arterial programme in the aorta-gonad-mesonephros embryonic region.

  4. Tumor promoting effect of low-dosage inhibition needs to be considered when implementing Delta-like (show DLK1 Antibodies) 4 targeting therapies.

  5. The heart defects in Dll4-/- embryos are consistent with primary defects in vessel patterning.

  6. DLL4 is an efficient cis (show CISH Antibodies)-inhibitor of Notch (show NOTCH1 Antibodies) signaling during embryogenesis.

  7. Macrophage Dll4 promotes lesion development in vein grafts via macrophage activation and crosstalk between macrophages and smooth muscle cells.

  8. work reveals how lymphatic vessel responses are shaped by tissue specialization and uncover a role for continuous DLL4 signaling in the function of adult lymphatic vasculature.

  9. Delta-like (show DLK1 Antibodies) 4-mediated Notch (show NOTCH1 Antibodies) signaling is required for early T-cell development in a three-dimensional thymic structure.

  10. Snail1 (show SNAI1 Antibodies) acts as a VEGF (show VEGFA Antibodies)-induced regulator of Notch1 (show NOTCH1 Antibodies) signalling and Dll4 expression. Results document a Snail1 (show SNAI1 Antibodies)-Dll4/Notch1 (show NOTCH1 Antibodies) axis that controls embryonic vascular development.

Zebrafish delta-Like 4 (DLL4) interaction partners

  1. show that blood flow suppresses vascular Notch (show NOTCH1 Antibodies) signalling via down-regulation of dll4

  2. Microinjection of miR (show MYLIP Antibodies)-30 mimics into zebrafish embryos resulted in suppression of dll4 and subsequent excessive sprouting of intersegmental vessels and reduction in dorsal aorta diameter.

  3. Notch (show NOTCH1 Antibodies) signalling pathway mutants Ectopic filopodia were also observed on the inter-somitic vessels of Notch (show NOTCH1 Antibodies) signalling pathway mutants. Ectopic filopodia are not due to loss of dll4.

  4. These studies imply critical roles for Dll4/Notch (show NOTCH1 Antibodies) signaling in the formation and wiring of the lymphatic network.

  5. Dll4-Notch signalling acts as an angiogenic ;off' switch by making endothelial cells unresponsive to Vegf.

  6. Vegfc (show VEGFC Antibodies)/Flt4 (show FLT4 Antibodies) signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries.

DLL4 Antigen Profile

Antigen Summary

This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.

Alternative names and synonyms associated with DLL4

  • delta-like 4 (Drosophila) (DLL4) antibody
  • delta-like 4 (Drosophila) (Dll4) antibody
  • delta-like 4 (Drosophila) (dll4) antibody
  • Delta4 antibody
  • hdelta2 antibody
  • si:ch211-244p18.5 antibody
  • zgc:136596 antibody

Protein level used designations for anti-delta-Like 4 (DLL4) Antibodies

delta-like protein 4 , delta 4 , delta ligand 4 , delta-like 4 homolog , delta-like 4 protein , delta4 , drosophila Delta homolog 4 , notch ligand DLL4 , notch ligand delta-2

GENE ID SPECIES
100057073 Equus caballus
100152163 Sus scrofa
54567 Homo sapiens
54485 Mus musculus
311332 Rattus norvegicus
453344 Pan troglodytes
607575 Canis lupus familiaris
518746 Bos taurus
563920 Danio rerio
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