DLL4 antibody (Extracellular Domain)

Catalog No. ABIN1169263

Product Details anti-DLL4 Antibody

Target: DLL4 (delta-Like 4 (DLL4))

Binding Specificity: Extracellular Domain

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLL4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Recognizes human DLL4.

Cross-Reactivity: Human

Sterility: 0.2 μm filtered

Immunogen: Recombinant human DLL4 (extracellular domain).

Clone: DL86-3AG

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Alternative Name: DLL4 (DLL4 Products)

Synonyms: hdelta2 antibody, Delta4 antibody, si:ch211-244p18.5 antibody, zgc:136596 antibody, delta like canonical Notch ligand 4 antibody, delta-like 4 (Drosophila) antibody, DLL4 antibody, Dll4 antibody, dll4 antibody

Background: The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

UniProt: Q9NR61

Pathways: Notch Signaling