DLL4 antibody (Extracellular Domain)
Quick Overview for DLL4 antibody (Extracellular Domain) (ABIN1169263)
Target
See all DLL4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- Extracellular Domain
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Specificity
- Recognizes human DLL4.
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Cross-Reactivity
- Human
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Sterility
- 0.2 μm filtered
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Immunogen
- Recombinant human DLL4 (extracellular domain).
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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Preservative
- Without preservative
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
Expiry Date
- 12 months
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- DLL4 (delta-Like 4 (DLL4))
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Alternative Name
- DLL4
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Background
- The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
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UniProt
- Q9NR61
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Pathways
- Notch Signaling
Target
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