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Browse our Notch1 Proteins (NOTCH1)

Full name:
Notch 1 Proteins (NOTCH1)
On www.antibodies-online.com are 11 Notch 1 (NOTCH1) Proteins from 3 different suppliers available. Additionally we are shipping Notch1 Antibodies (375) and Notch1 Kits (17) and many more products for this protein. A total of 417 Notch1 products are currently listed.
Synonyms:
9930111A19Rik, hN1, lin-12, Mis6, N1, NOTCH, notch-1, NOTCH1, notch1-a, Tan1, xnotch, xnotch1, Xotch
list all proteins Gene Name GeneID UniProt
NOTCH1 4851 P46531
NOTCH1 18128 Q01705
Rat NOTCH1 NOTCH1 25496  

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Notch1 Proteins (NOTCH1) by Origin

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Top referenced Notch1 Proteins

  1. Mouse (Murine) Notch1 Primary Antibody for SDS - ABIN1344230 : Fiorini, Merck, Wilson, Ferrero, Jiang, Koch, Auderset, Laurenti, Tacchini-Cottier, Pierres, Radtke, Luther, Macdonald: Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

More Proteins for Notch1 Interaction Partners

Pig (Porcine) Notch 1 (NOTCH1) interaction partners

  1. Notch1 regulates the proliferation of porcine satellite cells through the activation of Hes5 (show HES5 Proteins).

Human Notch 1 (NOTCH1) interaction partners

  1. Notch signaling plays a critical role in TGF-beta1 (show TGFB1 Proteins)-induced epithelial-to-mesenchymal transition in vitro proliferative vitreoretinopathy (PVR) model, (show PVR Proteins)which provides a novel insight into the pathogenesis of PVR

  2. arcinol treatment led to the upregulation of several tumor suppressor microRNAs, and miR (show MLXIP Proteins)-200c increased by garcinol treatment was found to target and downregulate Notch1

  3. NOTCH1 ligand Delta-like 1 (show DLL1 Proteins) homolog (DLK1 (show DLK1 Proteins)) self interacts

  4. it was demonstrated that GPR4 (show GPR4 Proteins) affects ECs by regulating Notch1, a function that may be important for physiological and pathological angiogenesis.

  5. NOTCH1 c.7544_7545delCT mutation resulting in removal of the C-terminal PEST domain, deregulation of NOTCH1-dependent signaling pathways, has negative influence on prognosis of chronic lymphocytic leukemia and efficiency of therapy with anti-CD20 (show MS4A1 Proteins) monoclonal antibodies.

  6. the results of the present study suggested that upregulation of Notch1 is involved in the chemotherapy resistance and tumor recurrence of glioblastoma.

  7. quid chewing is highly associated with NOTCH1 somatic mutations (especially with changes in EGF (show EGF Proteins)-like domains), and rs139994842 may potentially serve as an early predictive and prognostic biomarker for the occurrence and development of head and neck squamous cell carcinoma

  8. The upregulation of miR (show MLXIP Proteins)-146a in glioma cells through miR (show MLXIP Proteins)-146a mimic transfection led to reduction of cell viability and to an increase in the percentage of apoptosis. Notch1 was the name of the potential targeted gene for miR (show MLXIP Proteins)-146a in glioma.

  9. Overexpression of the Notch1 signaling pathway may represent a potential mechanism underlying the differentiation of hBMSCs.

  10. Subsequent mechanistic investigation indicated that cadherin 1 (CDH1 (show CDH1 Proteins))/beta-catenin (show CTNNB1 Proteins) signaling and Notch-1/Akt (show AKT1 Proteins) signaling were the downstream pathways of miR (show MLXIP Proteins)-92a-3p in glioma cells and glioma stem-like cells, respectively

Mouse (Murine) Notch 1 (NOTCH1) interaction partners

  1. Mice lacking endothelial Notch1 share some organ-specific vascular defects with ADAM10 (show ADAM10 Proteins)-deficient mice.

  2. Notch signaling plays a critical role in TGF-beta1 (show TGFB1 Proteins)-induced epithelial-to-mesenchymal transition in vitro and mice proliferative vitreoretinopathy (PVR (show PVRL2 Proteins)) model, which provides a novel insight into the pathogenesis of PVR (show PVRL2 Proteins)

  3. During cardiac valve formation, Notch1 signaling leads to epithelial-mesenchymal transition and cushion formation.

  4. NOTCH1 ligand Delta-like 1 (show DLL1 Proteins) homolog (DLK1 (show DLK1 Proteins)) self interacts

  5. Data suggest that expression, processing, and activation of (that is, signal transduction via) Notch1 (neurogenic locus notch homolog protein 1), Pten (phosphatase and tensin homolog), and Akt1 (thymoma viral proto-oncogene 1) are involved in oogenesis; oogenesis proceeds via both recruitment of primordial follicles and proliferation of granulosa cells.

  6. The combination of crocodile choline and Notch1 short interfering RNA led to dramatically increased cytotoxicity than observed with either agent alone. Notch1 short interfering RNA sensitized and potentiated the capability of crocodile choline to suppress the cell progression and invasion of gastric cancer

  7. Data show that liver progenitors differentiate into hepatocytes and cholangiocytes via transforming growth factor beta (TGFbeta (show TGFB1 Proteins)) treatment and Notch receptors.

  8. miR (show MLXIP Proteins)-342-5p acts as a multifunctional angiogenic repressor mediating the effects and interaction among angiogenic Notch1/VEGF (show VEGFA Proteins)/TGF-beta (show TGFB1 Proteins) signaling pathways.

  9. This study showed the effects of VEGF on excitatory synaptic transmission but also defines a role for the Notch1 receptor in mediating the response of synaptic activity to VEGF.

  10. we identified Notch1 signaling as a key determinant of triacylglycerol metabolism in response to a high fat diet, and we further revealed novel biological actions of Notch1 signaling pathways on the regulation of lipid oxidation.

Xenopus laevis Notch 1 (NOTCH1) interaction partners

  1. Notch initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3

  2. Notch signaling promotes floor plate and hypochord fates over notochord, but has variable effects on Shh (show SHH Proteins) expression in the midline.

  3. Transgenic tadpoles were prepared with an elastase promoter driving either the stromelysin-3 (show MMP11 Proteins) gene or the constitutively active form of Notch (IC).

  4. ZFP423 coordinates Notch1 and bone morphogenetic protein signaling, selectively up-regulating Hes5 (show HES5 Proteins) gene expression.

  5. results suggest that a cell-to-cell interaction via the Notch/Su(H (show RBPJ Proteins)) pathway has a significant role in the PGC (show PGC Proteins) migration by regulating cell motility

  6. the process of delimiting the three germ layers requires Notch signaling.

  7. BCL6 (show BCL6 Proteins) inhibits transcription by competing for the Notch1 intracellular domain, preventing the coactivator Mastermind-like1 (MAM1 (show MAML1 Proteins)) from binding.

  8. the combination of XSICD-mediated intracellular signaling and the extracellular domain of Notch ligands-mediated activation of Notch receptor is involved in the primary neurogenesis

  9. Notch signaling is activated when activin-like signaling induces various tissues from homogenous undifferentiated cells.

  10. Notch controls smad2 (show SMAD2 Proteins) nuclear localization and the competence of ectodermal cells for activin A (show INHBA Proteins) in Xenopus embryos

Cow (Bovine) Notch 1 (NOTCH1) interaction partners

  1. bovine herpesvirus 1 ORF2 protein reduced the trans-activation potential of Notch1 and Notch3 (show NOTCH3 Proteins), suggesting that ORF2 interfered with the trans-activation potential of Notch.

  2. Cellular size or Notch1 expression is not per se a specific marker for mesenchymal progenitor cells in adult articular cartilage.

Notch1 (NOTCH1) Protein Profile

Protein Summary

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.

Alternative names and synonyms associated with Notch1 (NOTCH1)

  • notch 1 (notch1)
  • notch 1 (NOTCH1)
  • Notch homolog 1, translocation-associated (Drosophila) (NOTCH1)
  • Notch homolog 1, translocation-associated (NOTCH1)
  • notch 1 (Notch1)
  • 9930111A19Rik protein
  • hN1 protein
  • lin-12 protein
  • Mis6 protein
  • N1 protein
  • NOTCH protein
  • notch-1 protein
  • NOTCH1 protein
  • notch1-a protein
  • Tan1 protein
  • xnotch protein
  • xnotch1 protein
  • Xotch protein

Protein level used designations for Notch 1 Proteins (NOTCH1)

notch 1 , Notch homolog 1, translocation-associated (Drosophila) , Notch homolog 1, translocation-associated , neurogenic locus notch homolog protein 1 , translocation-associated notch protein TAN-1 , Motch A , Notch gene homolog 1 , mT14 , major type A protein , p300 , transmembrane receptor Notch1 , Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila) , neurogenic locus notch protein homolog , NOTCH-1

GENE ID SPECIES
100190917 Oncorhynchus mykiss
100631526 Amphimedon queenslandica
720888 Macaca mulatta
100037842 Xenopus (Silurana) tropicalis
100068764 Equus caballus
100144593 Sus scrofa
100224074 Taeniopygia guttata
4851 Homo sapiens
18128 Mus musculus
25496 Rattus norvegicus
394367 Xenopus laevis
395655 Gallus gallus
464865 Pan troglodytes
480676 Canis lupus familiaris
767866 Bos taurus
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