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Browse our Notch1 Proteins (NOTCH1)

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Notch 1 Proteins (NOTCH1)
On are 11 Notch 1 (NOTCH1) Proteins from 3 different suppliers available. Additionally we are shipping Notch1 Antibodies (300) and Notch1 Kits (11) and many more products for this protein. A total of 336 Notch1 products are currently listed.
9930111A19Rik, hN1, lin-12, Mis6, N1, NOTCH, notch-1, NOTCH1, notch1-a, Tan1, xnotch, xnotch1, Xotch
list all proteins Gene Name GeneID UniProt
NOTCH1 4851 P46531
NOTCH1 18128 Q01705
Rat NOTCH1 NOTCH1 25496  

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Notch1 Proteins (NOTCH1) by Origin

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Top referenced Notch1 Proteins

  1. Mouse (Murine) Notch1 Protein expressed in CHO Cells - ABIN1344230 : Fiorini, Merck, Wilson, Ferrero, Jiang, Koch, Auderset, Laurenti, Tacchini-Cottier, Pierres, Radtke, Luther, Macdonald: Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

More Proteins for Notch1 Interaction Partners

Pig (Porcine) Notch 1 (NOTCH1) interaction partners

  1. Notch1 regulates the proliferation of porcine satellite cells through the activation of Hes5 (show HES5 Proteins).

Human Notch 1 (NOTCH1) interaction partners

  1. TF3 suppressed the cleavage of Notch-1, subsequently decreased the expression of c-Myc, HIF-1a and VEGF, and finally the impaired cancer cells induced angiogenesis

  2. The expression of cytoplasmic Notch1 or nuclear Notch4 (show NOTCH4 Proteins) could also be upregulated by HBx in HepG2X cells. The upregulation of Notch1 by HBx was through p38 MAPK (show MAPK14 Proteins) pathway.

  3. Notch1 over-expression indicated aggressive biological behaviors

  4. a neighbor of NOTCH1, Lnc-RP11 (show PRPF31 Proteins)-611D20.2 (named NALT) which could regulate the NOTCH1 signal pathway through cis (show CISH Proteins)-regulation, was identified.

  5. GATA3 (show GATA3 Proteins)-mediated positive and negative feedback mechanisms via restraining Notch1 activity control human T-cell lineage commitment.

  6. knockdown of Cav-1 (show CAV1 Proteins) was also able to significantly downregulate the protein expression level of Notch-1, p-Akt (show AKT1 Proteins) and p-NF-kappaB (show NFKB1 Proteins) p65 (show GORASP1 Proteins) in cisplatin-resistant ovarian cancer cells.

  7. Thymoquinone inhibits hepatocellular carcinoma cell growth by inducing cell cycle arrest and apoptosis, achieving these effects by repression of the Notch signaling pathway.

  8. The status of Notch1 is useful for predicting the prognosis of patients with early stage hepatocellular carcinoma undergoing hepatectomy.

  9. Notch1 expression is increased in human LSCC and correlates with tumorigenesis and metastasis, while in HEp (show EPHB6 Proteins)-2 cells, Notch1 knockdown inhibited cell growth, induced apoptosis and inhibited migration and invasion by regulating Notch1 target genes.

  10. These results suggested that the upregulation of notch1 and KRT6B (show KRT6B Proteins) might be involved in the development, progression and prognosis of human renal cell carcinoma (show MOK Proteins)

Mouse (Murine) Notch 1 (NOTCH1) interaction partners

  1. the cardioprotective effect of Notch1 against ischemic damage is mediated by AMPK (show PRKAA1 Proteins) signaling via an interaction with upstream LKB1 (show STK11 Proteins).

  2. Epidermal Notch1 recruits RORgamma(+) group 3 innate lymphoid cells to orchestrate normal skin repair.

  3. Jagged1 (show JAG1 Proteins) intracellular domain-mediated inhibition of Notch1 signalling regulates cardiac homeostasis in the postnatal heart.

  4. Data show that the proliferation of sustained expression of Notch1-induced choroid plexus (CP) tumours relies on Sonic Hedgehog (Shh (show SHH Proteins)) from the tumour microenvironment through their primary cilium.

  5. The physical interaction of NBEA with NOTCH1 is most relevant for autism spectrum disorders pathogenesis because NOTCH signaling is essential for neural development.

  6. LFNG (show LFNG Proteins) protein may have context-dependent effects on Notch activity

  7. A transgenic mouse model in which the Notch1 intracellular domain (NIC (show NCSTN Proteins)) is activated.

  8. Dll4 (show DLL4 Proteins)/Notch signaling and HIF-1alpha (show HIF1A Proteins) are closely related to lymphangiogenesis in dry eye-induced lacrimal glands.

  9. generated a model to study the consequence of increased Notch signaling in female reproduction and provide the first evidence, to our knowledge, that Notch signaling can regulate epigenetic modification of the progesterone receptor (show PGR Proteins)

  10. Autophagy impacts stem cell differentiation by degrading Notch1.

Xenopus laevis Notch 1 (NOTCH1) interaction partners

  1. Notch initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3

  2. Notch signaling promotes floor plate and hypochord fates over notochord, but has variable effects on Shh (show SHH Proteins) expression in the midline.

  3. Transgenic tadpoles were prepared with an elastase promoter driving either the stromelysin-3 (show MMP11 Proteins) gene or the constitutively active form of Notch (IC).

  4. ZFP423 coordinates Notch1 and bone morphogenetic protein signaling, selectively up-regulating Hes5 (show HES5 Proteins) gene expression.

  5. results suggest that a cell-to-cell interaction via the Notch/Su(H (show RBPJ Proteins)) pathway has a significant role in the PGC (show PGC Proteins) migration by regulating cell motility

  6. the process of delimiting the three germ layers requires Notch signaling.

  7. BCL6 (show BCL6 Proteins) inhibits transcription by competing for the Notch1 intracellular domain, preventing the coactivator Mastermind-like1 (MAM1 (show MAML1 Proteins)) from binding.

  8. the combination of XSICD-mediated intracellular signaling and the extracellular domain of Notch ligands-mediated activation of Notch receptor is involved in the primary neurogenesis

  9. Notch signaling is activated when activin-like signaling induces various tissues from homogenous undifferentiated cells.

  10. Notch controls smad2 (show SMAD2 Proteins) nuclear localization and the competence of ectodermal cells for activin A (show INHBA Proteins) in Xenopus embryos

Cow (Bovine) Notch 1 (NOTCH1) interaction partners

  1. bovine herpesvirus 1 ORF2 protein reduced the trans-activation potential of Notch1 and Notch3 (show NOTCH3 Proteins), suggesting that ORF2 interfered with the trans-activation potential of Notch.

  2. Cellular size or Notch1 expression is not per se a specific marker for mesenchymal progenitor cells in adult articular cartilage.

Notch1 (NOTCH1) Protein Profile

Protein Summary

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.

Alternative names and synonyms associated with Notch1 (NOTCH1)

  • notch 1 (notch1)
  • notch 1 (NOTCH1)
  • Notch homolog 1, translocation-associated (Drosophila) (NOTCH1)
  • Notch homolog 1, translocation-associated (NOTCH1)
  • notch 1 (Notch1)
  • 9930111A19Rik protein
  • hN1 protein
  • lin-12 protein
  • Mis6 protein
  • N1 protein
  • NOTCH protein
  • notch-1 protein
  • NOTCH1 protein
  • notch1-a protein
  • Tan1 protein
  • xnotch protein
  • xnotch1 protein
  • Xotch protein

Protein level used designations for Notch 1 Proteins (NOTCH1)

notch 1 , Notch homolog 1, translocation-associated (Drosophila) , Notch homolog 1, translocation-associated , neurogenic locus notch homolog protein 1 , translocation-associated notch protein TAN-1 , Motch A , Notch gene homolog 1 , mT14 , major type A protein , p300 , transmembrane receptor Notch1 , Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila) , neurogenic locus notch protein homolog , NOTCH-1

100190917 Oncorhynchus mykiss
100631526 Amphimedon queenslandica
720888 Macaca mulatta
100037842 Xenopus (Silurana) tropicalis
100068764 Equus caballus
100144593 Sus scrofa
100224074 Taeniopygia guttata
4851 Homo sapiens
18128 Mus musculus
25496 Rattus norvegicus
394367 Xenopus laevis
395655 Gallus gallus
464865 Pan troglodytes
480676 Canis lupus familiaris
767866 Bos taurus
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