Browse our anti-NOTCH2 (NOTCH2) Antibodies

Full name:
anti-Notch 2 Antibodies (NOTCH2)
On www.antibodies-online.com are 201 Notch 2 (NOTCH2) Antibodies from 25 different suppliers available. Additionally we are shipping NOTCH2 Kits (17) and NOTCH2 Proteins (12) and many more products for this protein. A total of 239 NOTCH2 products are currently listed.
Synonyms:
AGS2, AI853703, HJCYS, hN2, N2, notch6, sb:cb884
list all antibodies Gene Name GeneID UniProt
NOTCH2 4853 Q04721
NOTCH2 18129 O35516
NOTCH2 29492 Q9QW30

Show all species

Show all synonyms

Most Popular Reactivities for anti-NOTCH2 (NOTCH2) Antibodies

Select your species and application

anti-Human NOTCH2 Antibodies:

anti-Mouse (Murine) NOTCH2 Antibodies:

anti-Rat (Rattus) NOTCH2 Antibodies:

All available anti-NOTCH2 Antibodies

Go to our pre-filtered search.

Top referenced anti-NOTCH2 Antibodies

  1. Mouse (Murine) Monoclonal NOTCH2 Primary Antibody for FACS - ABIN2663857 : Kraman, McCright: Functional conservation of Notch1 and Notch2 intracellular domains. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 (PubMed)
    Show all 6 references for 2663857

  2. Human Polyclonal NOTCH2 Primary Antibody for ELISA - ABIN1043688 : Bertrand, Eckfeldt, Lysholm, LeBien: Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells. in Leukemia 2001 (PubMed)
    Show all 2 references for 1043688

  3. Human Polyclonal NOTCH2 Primary Antibody for EIA, IF - ABIN303122 : Siar, Ha, Aung, Nakano, Tsujigiwa, Nagatsuka, Ng, Kawakami: Immunolocalization of notch signaling protein molecules in a maxillary chondrosarcoma and its recurrent tumor. in European journal of medical research 2010 (PubMed)
    Show all 2 references for 303122

  4. Human Polyclonal NOTCH2 Primary Antibody for ELISA, WB - ABIN185523 : Schwarzmeier, Hubmann, Düchler, Jäger, Shehata: Regulation of CD23 expression by Notch2 in B-cell chronic lymphocytic leukemia. in Leukemia & lymphoma 2004 (PubMed)

  5. Human Polyclonal NOTCH2 Primary Antibody for ELISA, WB - ABIN1536150 : Blaumueller, Qi, Zagouras, Artavanis-Tsakonas: Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. in Cell 1997 (PubMed)

  6. Cow (Bovine) Polyclonal NOTCH2 Primary Antibody for WB - ABIN2777549 : Tilley, Harvey, Heguy, Hackett, Wang, OConnor, Crystal: Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease. in American journal of respiratory and critical care medicine 2009 (PubMed)

More Antibodies against NOTCH2 Interaction Partners

Human Notch 2 (NOTCH2) interaction partners

  1. In conclusion, Notch (show NOTCH1 Antibodies) siganling appears to be an important mediator of the liver inflammation by modulating hepatic IL-22 (show IL22 Antibodies)-secreting NKp46 (show NCR1 Antibodies)(+) innate lymphoid cells.

  2. The data showed that the overexpression of miR (show MLXIP Antibodies)-18a-5p could downregulate Notch2 expression and subsequently suppress endothelial-mesenchymal transition and cardiac fibrosis.

  3. Major genomic mutation profiles in lacrimal gland adenoid cystic carcinoma (LGACC) were uncovered by exome-seq. Although preliminary in nature, the Notch (show NOTCH1 Antibodies) pathway could be a potential therapeutic target for LGACC.

  4. Data indicate that mRNA high expression level of Notch1 (show NOTCH1 Antibodies) was associated with better overall survival (OS) for all NSCLC, hazard ratio (HR), better OS in adenocarcinoma (Ade), HR, as well as in squamous cell carcinoma (SCC (show CYP11A1 Antibodies)), HR, and mRNA high expression levels of Notch2 and Notch3 (show NOTCH3 Antibodies) were associated with worsen OS for all NSCLC, and mRNA high expression level of Notch4 (show NOTCH4 Antibodies) was not found to be associated with to OS for all NSCLC.

  5. Mutation in NOTCH2 gene is associated with nodal marginal zone lymphoma.

  6. Transgenic mice harboring Notch2 mutation analogous to that in patients with Hajdu-Cheney syndrome (HCS (show HLCS Antibodies)) are severely osteopenic because of enhanced bone resorption; this model has now been validated. Data from further studies in transgenic mice suggest that the HCS (show HLCS Antibodies) mutation in osteoblasts, but not in osteoclasts, causes osteopenia in this model.

  7. Intermittent compressive stress regulates Notch (show NOTCH1 Antibodies) receptor and target gene expression via the TGF-beta (show TGFB1 Antibodies) signaling pathway. Notch (show NOTCH1 Antibodies) signaling participates in TGF-beta (show TGFB1 Antibodies)-induced sclerostin (show SOST Antibodies) expression in periodontal ligament cells.

  8. The authors present novel structures of human ligands Jagged2 (show JAG2 Antibodies) and Delta-like4 and human Notch2, together with functional assays, which suggest that ligand-mediated coupling of membrane recognition and Notch (show NOTCH1 Antibodies) binding is likely to be critical in establishing the optimal context for Notch (show NOTCH1 Antibodies) signalling.

  9. Notch1 (show NOTCH1 Antibodies) and Notch2 are the primary Notch (show NOTCH1 Antibodies) receptors regulating epithelial cell homoeostasis in mouse and human stomach.

  10. our results indicated epidermal growth factor (show EGF PLURAL_@26348@)-like domain multiple 7 protein participates in growth hormone (show GH1 PLURAL_@26348@)-secreting pituitary adenoma proliferation and invasion regulation via Notch2/DLL3 (show DLL3 PLURAL_@26348@) signaling pathway. These findings raised the possibility that epidermal growth factor (show EGF PLURAL_@26348@)-like domain multiple 7 protein might serve as a useful biomarker to assess growth hormone (show GH1 PLURAL_@26348@)-secreting pituitary adenoma invasion and prognosis

Mouse (Murine) Notch 2 (NOTCH2) interaction partners

  1. this study shows that Notch (show NOTCH1 Antibodies) signaling regulates basophils biological function, at least partially via the modulation of MAPK (show MAPK1 Antibodies)

  2. Postnatal development analysis revealed that in cilia-deficient corneal epithelial cells downregulation of the Notch (show NOTCH1 Antibodies) pathway precedes cell proliferation defects.

  3. The data showed that the overexpression of miR (show MLXIP Antibodies)-18a-5p could downregulate Notch2 expression and subsequently suppress endothelial-mesenchymal transition and cardiac fibrosis.

  4. these results show that ADAM10 (show ADAM10 Antibodies)-Notch (show NOTCH1 Antibodies) signaling in ovarian somatic cells governs the primordial follicle formation by controlling the development of ovarian pregranulosa cells.

  5. Transgenic mice harboring Notch2 mutation analogous to that in patients with Hajdu-Cheney syndrome (HCS (show HLCS Antibodies)) are severely osteopenic because of enhanced bone resorption; this model has now been validated. Data from further studies in transgenic mice suggest that the HCS (show HLCS Antibodies) mutation in osteoblasts, but not in osteoclasts, causes osteopenia in this model.

  6. Notch1 (show NOTCH1 Antibodies) and Notch2 are the primary Notch (show NOTCH1 Antibodies) receptors regulating epithelial cell homoeostasis in mouse and human stomach.

  7. These results suggested that Notch2 signaling is linked to c-Myc (show MYC Antibodies) expression and plays a key role in the regulation of MSC (show MSC Antibodies) proliferation.

  8. this study shows that Notch2 activity is required for the maintenance of lung tissue-resident memory CD103 (show ITGAE Antibodies)+ T cells

  9. In this study, authors use a smooth muscle-specific (show EIF3K Antibodies) deletion of Notch2 together with a global Notch3 (show NOTCH3 Antibodies) deletion to produce mice with combinations of mutant and wild-type Notch2/3 alleles in vascular smooth muscle cells

  10. 6955C-->T mutation in the Notch2 locus leading to cancellous and cortical bone osteopenia.

Cow (Bovine) Notch 2 (NOTCH2) interaction partners

  1. bovine herpesvirus 1 ORF2 protein reduced the trans-activation potential of Notch1 (show NOTCH1 Antibodies) and Notch3 (show NOTCH3 Antibodies), suggesting that ORF2 interfered with the trans-activation potential of Notch (show NOTCH1 Antibodies).

Zebrafish Notch 2 (NOTCH2) interaction partners

  1. DeltaC/Notch1a (show NOTCH1A Antibodies) and Notch2 signaling is responsible for a survival signal provided by xanthophores to melanophores.

NOTCH2 Antigen Profile

Antigen Summary

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NOTCH2

  • notch 2 (NOTCH2) antibody
  • notch 2 (notch2) antibody
  • notch 2 (Notch2) antibody
  • notch homolog 2 (notch2) antibody
  • AGS2 antibody
  • AI853703 antibody
  • HJCYS antibody
  • hN2 antibody
  • N2 antibody
  • notch6 antibody
  • sb:cb884 antibody

Protein level used designations for anti-Notch 2 (NOTCH2) Antibodies

notch 2 , neurogenic locus notch homolog protein 2-like , Notch homolog 2 , neurogenic locus notch homolog protein 2 , Motch B , Notch gene homolog 2 , notch gene homolog 2 , notch receptor protein 6

GENE ID SPECIES
581186 Strongylocentrotus purpuratus
100081510 Ornithorhynchus anatinus
100464781 Ailuropoda melanoleuca
100567900 Anolis carolinensis
100584613 Nomascus leucogenys
100224680 Taeniopygia guttata
4853 Homo sapiens
457173 Pan troglodytes
483148 Canis lupus familiaris
18129 Mus musculus
29492 Rattus norvegicus
100153369 Sus scrofa
513730 Bos taurus
58065 Danio rerio
Selected quality suppliers for anti-NOTCH2 (NOTCH2) Antibodies
Did you look for something else?