NOTCH2 antibody

Catalog No. ABIN2475916

Cited in 3+ publications. The Hamster Monoclonal anti-NOTCH2 antibody (Clone HMN2-35) (ABIN2475916) specifically detects NOTCH2 in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for NOTCH2 antibody (ABIN2475916)

Target: NOTCH2 (Notch 2 (NOTCH2))

Reactivity: Mouse, Rat

Host: Hamster

Clonality: Monoclonal

Conjugate: This NOTCH2 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: HMN2-35

Product Details anti-NOTCH2 Antibody

Cross-Reactivity: Rat (Rattus)

Characteristics: Purified IgG

Purification: Purified

Immunogen: Mouse Notch 2-Fc fusion protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-NOTCH2 antibody (ABIN2475916)

Gibb, El Shikh, Kang, Rowe, El Sayed, Cichy, Yagita, Tew, Dempsey, Crawford, Conrad: "ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo." in: The Journal of experimental medicine, Vol. 207, Issue 3, pp. 623-35, (2010) (PubMed).

Sekine, Moriyama, Koyanagi, Koyama, Ogata, Okumura, Yagita: "Differential regulation of splenic CD8- dendritic cells and marginal zone B cells by Notch ligands." in: International immunology, Vol. 21, Issue 3, pp. 295-301, (2009) (PubMed).

Moriyama, Sekine, Koyanagi, Koyama, Ogata, Chiba, Hirose, Okumura, Yagita: "Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice." in: International immunology, Vol. 20, Issue 6, pp. 763-73, (2008) (PubMed).

Target Details for NOTCH2

Target: NOTCH2 (Notch 2 (NOTCH2))

Alternative Name: NOTCH 2

Gene ID: 18129, 29492

UniProt: O35516, Q9QW30

Pathways: Notch Signaling, Stem Cell Maintenance