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Browse our anti-RBPJ (RBPJ) Antibodies

Full name:
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region Antibodies (RBPJ)
On www.antibodies-online.com are 83 Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) Antibodies from 19 different suppliers available. Additionally we are shipping RBPJ Proteins (8) and many more products for this protein. A total of 97 RBPJ products are currently listed.
Synonyms:
AI843960, AOS3, CBF1, csl, Igkjrb, IGKJRB1, Igkrsbp, KBF2, RBP-J, RBP-J kappa, RBPjk, Rbpsuh, Su(H), SUH, XSu(H), xsu(h)1
list all antibodies Gene Name GeneID UniProt
RBPJ 679028  
RBPJ 3516 Q06330
RBPJ 19664 P31266

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Most Popular Reactivities for anti-RBPJ (RBPJ) Antibodies

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anti-Rat (Rattus) RBPJ Antibodies:

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anti-Mouse (Murine) RBPJ Antibodies:

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Top referenced anti-RBPJ Antibodies

  1. Cow (Bovine) Polyclonal RBPJ Primary Antibody for IP, IHC - ABIN2777213 : MacKenzie, Duriez, Larrivée, Chang, Pollet, Wong, Yip, Karsan: Notch4-induced inhibition of endothelial sprouting requires the ankyrin repeats and involves signaling through RBP-Jkappa. in Blood 2004 (PubMed)

  2. Human Monoclonal RBPJ Primary Antibody for ChIP, EMSA - ABIN2668822 : Ehm, Göritz, Covic, Schäffner, Schwarz, Karaca, Kempkes, Kremmer, Pfrieger, Espinosa, Bigas, Giachino, Taylor, Frisén, Lie: RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)

  3. Human Monoclonal RBPJ Primary Antibody for WB - ABIN2668739 : Maier, Santak, Mantik, Grabusic, Kremmer, Hammerschmidt, Kempkes et al.: A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 ... in Journal of virology 2005 (PubMed)

More Antibodies against RBPJ Interaction Partners

Human Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) interaction partners

  1. RBPJ polymorphism [rs874040(CC) allele] skews memory T cells toward a pro-inflammatory phenotype involving Notch (show NOTCH1 Antibodies) signaling, thus increasing the susceptibility to develop rheumatoid arthritis.

  2. The role of CSL (show CSHL1 Antibodies)-dependent and independent Notch (show NOTCH1 Antibodies) signaling pathways in cell apoptosis is described in normal tissue homeostasis and in tumorigenesis. (Review)

  3. These results support a model in which EBNA2 and EBNA3s compete for distinct subsets of RBPJ sites to regulate cell genes and where EBNA3 (show EBNA-3A Antibodies) subset specificity is determined by interactions with other cell transcription factors.

  4. Suggest that hypoxia promotes SMO transcription through upregulation of MAML3 (show MAML3 Antibodies) and RBPJ to induce proliferation, invasiveness and tumorigenesis in pancreatic cancer.

  5. data suggest that shRNA intervention of RBPJ expression could be a promising therapeutic approach for treating human prostate cancer

  6. Cancer-associated fibroblast activation-stromal co-evolution is under convergent CSL (show CSHL1 Antibodies)-p53 (show TP53 Antibodies) control.

  7. Single nucleotide polymorphisms in RBPJ, IL1R1 (show IL1RN Antibodies), REV3L (show REV3L Antibodies), TRAF3IP2 (show TRAF3IP2 Antibodies), IRF1 (show IRF1 Antibodies) and ICOS (show CTLA4 Antibodies) showed association with rheumatoid arthritis in black South Africans.

  8. missense mutations and frameshift deletions identified in (show REN Antibodies)leukemia patients

  9. Our data thus suggest that shRNA intervention of RBPJ expression could be a promising therapeutic approach for treating human lung cancer.

  10. RBP-J-interacting and tubulin-associated (RITA (show C12orf52 Antibodies)) mediates the nuclear export of RBP-J to tubulin (show TUBB Antibodies) fibers and downregulates Notch (show NOTCH1 Antibodies)-mediated transcription.

Xenopus laevis Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) interaction partners

  1. findings reveal that, in response to Wnt (show WNT2 Antibodies) signalling, Dishevelled (show DVL2 Antibodies) inhibits CSL (show SMPX Antibodies) transcription factors to regulate Notch (show NOTCH1 Antibodies) signalling and cell-fate decisions in vivo

  2. The study reports the identification and functional characterization of rbpj interacting and tubulin associated (RITA) (C12ORF52 (show C12orf52 Antibodies)) as a novel rbpj/CBF-1-interacting protein.

  3. The results suggest that a cell-to-cell interaction via the Notch (show NOTCH1 Antibodies)/Su(H) pathway has a significant role in the PGC (show PGC Antibodies) migration by regulating cell motility.

  4. This "target protector and rescue assay" demonstrates that the phenotypic defects associated with CUGBP1 inactivation in Xenopus are essentially due to the deregulation of Su(H) mRNA.

Mouse (Murine) Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) interaction partners

  1. Rbpj-kappa mediated Notch (show NOTCH1 Antibodies) signaling plays a critical role in development of hypothalamic Kisspeptin neurons.

  2. Results reveal an essential role for canonical Notch (show NOTCH1 Antibodies)/RBP-J signaling in hippocampal synaptic plasticity and suggest that role, at least in part, is mediated by the regulation of GABAergic signaling

  3. The bone marrow contains a progenitor that expresses renin (show REN Antibodies) throughout development and possesses a B-lymphocyte (show AKAP17A Antibodies) pedigree. This cell requires RBP-J to differentiate.

  4. functions as a transcriptional repressor on the promoter of the microRNA miR (show MLXIP Antibodies)-155

  5. DNA methylation-dependent binding of RBPJ to a GC repressor element can negatively regulate smooth muscl myosin heavy chain promoter activity and can inhibit marker gene expression in phenotypically modulated cells

  6. Rbpj directly regulates the expression of uterine matrix metalloproteinase (show MMP20 Antibodies) in a Notch (show NOTCH1 Antibodies) pathway-dependent manner, which is required for normal post-implantation decidual remodeling.

  7. RBP-J maintains the identity of the renin (show REN Antibodies) cell by not only activating genes characteristic of the myo (show SYNPO2 Antibodies)-endocrine phenotype but also, preventing ectopic gene expression and adoption of an aberrant phenotype

  8. RBP-J-mediated Notch (show NOTCH1 Antibodies) signaling is required for macrophages to promote hepatic fibrosis by up-regulation of NF-kappaB (show NFKB1 Antibodies) activation through CYLD (show CYLD Antibodies).

  9. Environmental cues that regulate RBP-J expression/function potentially modulate the requirement for costimulatory signaling for osteoclast differentiation and bone remodeling.

  10. RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche.

RBPJ Antigen Profile

Antigen Summary

The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.

Alternative names and synonyms associated with RBPJ

  • recombination signal binding protein for immunoglobulin kappa J region (Rbpj) antibody
  • recombination signal binding protein for immunoglobulin kappa J region (RBPJ) antibody
  • recombination signal binding protein for immunoglobulin kappa J region (rbpj) antibody
  • AI843960 antibody
  • AOS3 antibody
  • CBF1 antibody
  • csl antibody
  • Igkjrb antibody
  • IGKJRB1 antibody
  • Igkrsbp antibody
  • KBF2 antibody
  • RBP-J antibody
  • RBP-J kappa antibody
  • RBPjk antibody
  • Rbpsuh antibody
  • Su(H) antibody
  • SUH antibody
  • XSu(H) antibody
  • xsu(h)1 antibody

Protein level used designations for RBPJ

recombining binding protein suppressor of hairless , CBF-1 , H-2K binding factor-2 , RBP-J kappa , RBP-JK , immunoglobulin kappa J region recombination signal binding protein 1 , renal carcinoma antigen NY-REN-30 , suppressor of hairless homolog , X-Su(H) , suppressor of hairless protein 1 , suppressor of hairless protein homolog , J kappa-recombination signal-binding protein

GENE ID SPECIES
679028 Rattus norvegicus
3516 Homo sapiens
399453 Xenopus laevis
19664 Mus musculus
767928 Bos taurus
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