Browse our anti-CDKN1A (CDKN1A) Antibodies

Full name:
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) Antibodies (CDKN1A)
On www.antibodies-online.com are 566 Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) Antibodies from 24 different suppliers available. Additionally we are shipping CDKN1A Kits (13) and CDKN1A Proteins (13) and many more products for this protein. A total of 629 CDKN1A products are currently listed.
Synonyms:
CAP20, CCND1, CDKI, Cdkn1, CDKN1A, CIP1, MDA-6, mda6, p16Xic2, P21, p21Cip1, p21WAF, SDI1, si:ch1073-48m5.2, UV96, WAF1
list all antibodies Gene Name GeneID UniProt
CDKN1A 114851  
CDKN1A 1026 P38936
CDKN1A 12575 P39689

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Top referenced anti-CDKN1A Antibodies

  1. Human Polyclonal CDKN1A Primary Antibody for FACS, IF - ABIN391763 : Fukuchi, Nakamura, Ichimura, Tatsumi, Gomi: The association of cyclin A and cyclin kinase inhibitor p21 in response to gamma-irradiation requires the CDK2 binding region, but not the Cy motif. in Biochimica et biophysica acta 2003 (PubMed)
    Show all 5 references for 391763

  2. Human Polyclonal CDKN1A Primary Antibody for DB, EIA - ABIN358179 : Scott, Kimura, Dong, Ichinohasama, Bergen, Kerviche, Sheridan, DeCoteau: Methylation status of cyclin-dependent kinase inhibitor genes within the transforming growth factor beta pathway in human T-cell lymphoblastic lymphoma/leukemia. in Leukemia research 2004 (PubMed)
    Show all 5 references for 358179

  3. Human Polyclonal CDKN1A Primary Antibody for EIA, IHC (p) - ABIN358182 : Amini, Saunders, Kelley, Khalili, Sawaya: Interplay between HIV-1 Vpr and Sp1 modulates p21(WAF1) gene expression in human astrocytes. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for 358182

  4. Human Polyclonal CDKN1A Primary Antibody for EIA, IHC (p) - ABIN359673 : Frouin, Maga, Denegri, Riva, Savio, Spadari, Prosperi, Scovassi: Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for 359673

  5. Human Polyclonal CDKN1A Primary Antibody for IF, WB - ABIN653259 : Chen, Turner, McCarthy, Scaltriti, Bettuzzi, Yeatman: Clusterin-mediated apoptosis is regulated by adenomatous polyposis coli and is p21 dependent but p53 independent. in Cancer research 2004 (PubMed)
    Show all 3 references for 653259

  6. Human Polyclonal CDKN1A Primary Antibody for WB - ABIN655723 : Noma, Kirino, Ikeuchi, Suzuki: Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. in The EMBO journal 2006 (PubMed)
    Show all 2 references for 655723

  7. Human Monoclonal CDKN1A Primary Antibody for FACS, IHC (p) - ABIN180466 : Buckley, Sweeney, Hamilton, Sini, Manning, Nicholson, deFazio, Watts, Musgrove, Sutherland: Expression and amplification of cyclin genes in human breast cancer. in Oncogene 1993 (PubMed)
    Show all 2 references for 180466

  8. Human Polyclonal CDKN1A Primary Antibody for IF, IHC (p) - ABIN657391 : Hu, Gartenhaus, Eichberg, Liu, Fang, Rapoport: PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21. in Oncogene 2010 (PubMed)

  9. Human Polyclonal CDKN1A Primary Antibody for EIA, IHC (p) - ABIN358181 : Marqués, Kumar, Poveda, Zuluaga, Hernández, Jackson, Pasero, Carrera: Specific function of phosphoinositide 3-kinase beta in the control of DNA replication. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)

More Antibodies against CDKN1A Interaction Partners

Zebrafish Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (show CDK1 Antibodies), wee1 (show WEE1 Antibodies), p21, PCNA (show PCNA Antibodies) and cdk2 (show CDK2 Antibodies), but only weakly influences cyclin B1 (show CCNB1 Antibodies), cyclin B2 (show CCNB2 Antibodies) and cyclin E1 (show CCNE1 Antibodies) expression.

Human Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. MiR (show MLXIP Antibodies)-6734 inhibits the growth of colon cancer cells by up-regulating p21 gene expression.

  2. IFITM1 (show IFITM1 Antibodies) suppression blocks proliferation and invasion of aromatase (show CYP19A1 Antibodies) inhibitor-resistant breast cancer in vivo by JAK (show JAK3 Antibodies)/STAT1 (show STAT1 Antibodies)-mediated induction of p21.

  3. The results indicate that MF exposure can alter the G1 checkpoint response and that the p21 protein (show NRAS Antibodies) may be involved in early responses to MF exposure.

  4. Disruption of CK1alpha (show CSNK1A1 Antibodies) function in myeloma cells resulted in decreased Mdm2 (show MDM2 Antibodies), increased p53 (show TP53 Antibodies) and p21 and reduced expression of beta-catenin (show CTNNB1 Antibodies) and AKT (show AKT1 Antibodies).

  5. tumor-suppressor functions of SOCS1 (show SOCS1 Antibodies) in the liver could be mediated, at least partly, via regulation of the expression, stability and subcellular distribution of p21 and its paradoxical oncogenic functions, namely, resistance to apoptosis and increased proliferation

  6. Here, the authors show that the CDK (show CDK4 Antibodies) inhibitor p21 (CDKN1A) maintains the viability of DNA damage-induced senescent cells. Upon p21 knockdown, senescent cells acquired multiple DNA lesions that activated ataxia telangiectasia mutated (ATM (show ATM Antibodies)) and nuclear factor (NF)-kappaB (show NFKB1 Antibodies) kinase, leading to decreased cell survival. NF-kappaB (show NFKB1 Antibodies) activation induced TNF-alpha (show TNF Antibodies) secretion and JNK (show MAPK8 Antibodies) activation to mediate death of senescent cells in a...

  7. Data show that the resveratrol/docetaxel combination up regulated the expression of tumor supressor p53 (p53 (show TP53 Antibodies)), and cell cycle inhibitors p21WAF1/CIP1 and p27KIP1 (show CDKN1B Antibodies).

  8. these results demonstrated that the messenger RNA expression levels of p53 (show TP53 Antibodies) and p21 may have a relationship with the changes in telomere length induced by omethoate and provided strong evidence for the mechanism of canceration induced by poison.

  9. Overexpression of these two microRNAs in A549 induced cell-cycle arrest and cell senescence, delayed cell proliferation and colony formation, and inhibited migration and invasion. In conclusion, microRNA-mediated RNAa depends on the cell context, and miR (show MLXIP Antibodies)-1236 and miR (show MLXIP Antibodies)-370 can inhibit non-small-cell lung carcinoma cell growth by upregulating p21 expression in vitro

  10. this study shows that allergen exposure modulates miR (show MLXIP Antibodies)-132, and that repression of CDKN1A by allergen-induced miR (show MLXIP Antibodies)-132 may contribute to shedding of bronchial epithelial cells

Cow (Bovine) Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. p21 expression reports on Bovine herpesvirus 4 replication and could represent a host cell defensive response to infection-associated cellular damage.

Mouse (Murine) Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. FLT3 (show FLT3 Antibodies)-ITD is capable of inhibiting FLT3 (show FLT3 Antibodies)-ITD+ cell proliferation through the p21 (show D4S234E Antibodies)/Pbx1 (show PBX1 Antibodies) axis

  2. These data reveal a novel role for p21/waf1 in the resolution of inflammation via its ability to control neutrophil apoptosis.

  3. the silencing of Cyclin-dependent kinase 5 (show CDK5 Antibodies) preventing memory dysfunction

  4. Results show that p21 (show D4S234E Antibodies) expression is regulated by OLA1 (show OLA1 Antibodies) to promote cell proliferation and organogenesis.

  5. AS160 (show TBC1D4 Antibodies) regulates glucose-independent eukaryotic cell proliferation through p21 (show D4S234E Antibodies)-dependent control of the cell cycle.

  6. telomerase activity and cardiomyocyte telomere length decrease sharply in wild-type mouse hearts after birth, resulting in cardiomyocytes with dysfunctional telomeres and anaphase bridges and positive for the cell-cycle arrest protein p21 (show D4S234E Antibodies).

  7. Consistent with the latter, Arid1a (show ARID1A Antibodies) reexpression in tumor cells led to increased p21 (Cdkn1a) expression and dramatic accumulation of cells in G2 phase of the cell cycle. These results also indicate a potential opportunity for therapeutic intervention in ARID1A (show ARID1A Antibodies)-deficient human breast cancer subtypes that retain one intact copy of the gene and also maintain wild-type TRP53 (show TP53 Antibodies) activity

  8. We discovered that FXR1P (show FXR1 Antibodies)-deficient aNSCs have altered expression of a select number of cell-cycle genes, and we identified the mRNA of cyclin-dependent kinase inhibitor 1A (Cdkn1a, p21 (show D4S234E Antibodies)) as a direct target of FXR1P (show FXR1 Antibodies).

  9. These results demonstrate that CQ and AQ increase the expression level of p21 (show D4S234E Antibodies) and inhibit T cell proliferation and the development of IFN-gamma (show IFNG Antibodies)-producing Th1 (show HAND1 Antibodies) cells, thereby revealing beneficial roles in treating a wide range of chronic inflammatory diseases mediated by inflammatory T cells.

  10. increases the number of ALP (show CCL21A Antibodies)-positive colonies after iPSC induction and decreases expression levels of Eomes (show EOMES Antibodies) and p21 (show D4S234E Antibodies) mRNAs. Based on these observations, we propose that the CCR4 (show CCR4 Antibodies)-NOT deadenylase activity contributes to iPSC induction.

CDKN1A Antigen Profile

Antigen Summary

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene.

Alternative names and synonyms associated with CDKN1A

  • cyclin-dependent kinase inhibitor 1A (p21, Cip1) (cdkn1a) antibody
  • cyclin-dependent kinase inhibitor 1 (cki1) antibody
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A) antibody
  • cyclin-dependent kinase inhibitor 1A (cdkn1a) antibody
  • cyclin-dependent kinase inhibitor 1A (LOC100348489) antibody
  • cyclin-dependent kinase inhibitor 1A (Cdkn1a) antibody
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1) (Cdkn1a) antibody
  • cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a) antibody
  • CAP20 antibody
  • CCND1 antibody
  • CDKI antibody
  • Cdkn1 antibody
  • CDKN1A antibody
  • CIP1 antibody
  • MDA-6 antibody
  • mda6 antibody
  • p16Xic2 antibody
  • P21 antibody
  • p21Cip1 antibody
  • p21WAF antibody
  • SDI1 antibody
  • si:ch1073-48m5.2 antibody
  • UV96 antibody
  • WAF1 antibody

Protein level used designations for CDKN1A

cyclin dependent kinase inhibitor p16Xic2 , cyclin-dependent kinase inhibitor 1 , cyclin D1 , cyclin-dependent kinase inhibitor 1A (p21, Cip1) , cip1 , p21 , waf1 , cyclin-dependent kinase inhibitor 1A , cyclin-dependent kinase inhibitor 1A (P21) , CDK-interacting protein 1 , CDK-interaction protein 1 , DNA synthesis inhibitor , melanoma differentiation associated protein 6 , wild-type p53-activated fragment 1 , p21/WAF1 , melanoma differentiation-associated protein , p21

GENE ID SPECIES
492305 Xenopus laevis
606440 Zea mays
747442 Pan troglodytes
100038054 Xenopus (Silurana) tropicalis
100302083 Ovis aries
100151416 Danio rerio
100348489 Oryctolagus cuniculus
114851 Rattus norvegicus
1026 Homo sapiens
474890 Canis lupus familiaris
513497 Bos taurus
100152215 Sus scrofa
100720449 Cavia porcellus
493943 Felis catus
12575 Mus musculus
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