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Browse our anti-CDKN1A (CDKN1A) Antibodies

Full name:
anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) Antibodies (CDKN1A)
On are 579 Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) Antibodies from 23 different suppliers available. Additionally we are shipping CDKN1A Kits (14) and CDKN1A Proteins (14) and many more products for this protein. A total of 644 CDKN1A products are currently listed.
CAP20, CCND1, CDKI, Cdkn1, CDKN1A, CIP1, MDA-6, mda6, p16Xic2, P21, p21Cip1, p21WAF, SDI1, si:ch1073-48m5.2, UV96, WAF1
list all antibodies Gene Name GeneID UniProt
CDKN1A 114851  
CDKN1A 1026 P38936
CDKN1A 12575 P39689

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Top referenced anti-CDKN1A Antibodies

  1. Human Polyclonal CDKN1A Primary Antibody for FACS, IF - ABIN391763 : Fukuchi, Nakamura, Ichimura, Tatsumi, Gomi: The association of cyclin A and cyclin kinase inhibitor p21 in response to gamma-irradiation requires the CDK2 binding region, but not the Cy motif. in Biochimica et biophysica acta 2003 (PubMed)
    Show all 5 references for ABIN391763

  2. Human Polyclonal CDKN1A Primary Antibody for DB, EIA - ABIN358179 : Scott, Kimura, Dong, Ichinohasama, Bergen, Kerviche, Sheridan, DeCoteau: Methylation status of cyclin-dependent kinase inhibitor genes within the transforming growth factor beta pathway in human T-cell lymphoblastic lymphoma/leukemia. in Leukemia research 2004 (PubMed)
    Show all 5 references for ABIN358179

  3. Human Polyclonal CDKN1A Primary Antibody for EIA, IHC (p) - ABIN359673 : Frouin, Maga, Denegri, Riva, Savio, Spadari, Prosperi, Scovassi: Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN359673

  4. Human Polyclonal CDKN1A Primary Antibody for EIA, IHC (p) - ABIN358182 : Amini, Saunders, Kelley, Khalili, Sawaya: Interplay between HIV-1 Vpr and Sp1 modulates p21(WAF1) gene expression in human astrocytes. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358182

  5. Human Polyclonal CDKN1A Primary Antibody for IF, WB - ABIN653259 : Chen, Turner, McCarthy, Scaltriti, Bettuzzi, Yeatman: Clusterin-mediated apoptosis is regulated by adenomatous polyposis coli and is p21 dependent but p53 independent. in Cancer research 2004 (PubMed)
    Show all 3 references for ABIN653259

  6. Human Polyclonal CDKN1A Primary Antibody for WB - ABIN655723 : Noma, Kirino, Ikeuchi, Suzuki: Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. in The EMBO journal 2006 (PubMed)
    Show all 2 references for ABIN655723

  7. Human Monoclonal CDKN1A Primary Antibody for FACS, IHC (p) - ABIN180466 : Buckley, Sweeney, Hamilton, Sini, Manning, Nicholson, deFazio, Watts, Musgrove, Sutherland: Expression and amplification of cyclin genes in human breast cancer. in Oncogene 1993 (PubMed)
    Show all 2 references for ABIN180466

  8. Human Polyclonal CDKN1A Primary Antibody for IF, IHC (p) - ABIN657391 : Hu, Gartenhaus, Eichberg, Liu, Fang, Rapoport: PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21. in Oncogene 2010 (PubMed)

  9. Human Polyclonal CDKN1A Primary Antibody for EIA, IHC (p) - ABIN358181 : Marqués, Kumar, Poveda, Zuluaga, Hernández, Jackson, Pasero, Carrera: Specific function of phosphoinositide 3-kinase beta in the control of DNA replication. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)

More Antibodies against CDKN1A Interaction Partners

Zebrafish Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (show CDK1 Antibodies), wee1 (show WEE1 Antibodies), p21, PCNA (show PCNA Antibodies) and cdk2 (show CDK2 Antibodies), but only weakly influences cyclin B1 (show CCNB1 Antibodies), cyclin B2 (show CCNB2 Antibodies) and cyclin E1 (show CCNE1 Antibodies) expression.

Human Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. These results show that ASPL (show ASPSCR1 Antibodies)-TFE3 (show TFE3 Antibodies) regulates cell cycle progression and induces cellular senescence by up-regulating p21 expression.

  2. our study provides evidence that up-regulation of p21 is mainly responsible for the suppressive effect of miR (show MLXIP Antibodies)-1180-5p on human bladder cancer cells and miR (show MLXIP Antibodies)-1180-5p can significantly inhibit tumorigenicity in vivo.

  3. Low CIP1 expression is associated with renal cell carcinoma (show MOK Antibodies).

  4. RNA-binding motif 5 silencing reduced the messenger RNA and protein expression of the p53 (show TP53 Antibodies) target gene p21. Our results suggest that RNA-binding motif 5 downregulation is involved in gastric cancer progression and that RNA-binding motif 5 behaves as a tumor suppressor gene in gastric cancer

  5. These findings suggest that normal p53 (show TP53 Antibodies) function is crucial in ATM (show ATM Antibodies)/p53 (show TP53 Antibodies)/p21 pathway activated by LDIR. The p53 (show TP53 Antibodies) status is the most probable reason leading to differential LDIR biological activities between breast tumor cells and normal breast cells

  6. PPARg (show PPARG Antibodies) signaling pathway may involve in the proliferation inhibition of evodiamine on K562 cells via inhibiting cylcin D1 and stimulating of p21.

  7. CDKN1A expression is induced by miR (show MLXIP Antibodies)-3619-5p by directly targeting the putative site in the promoter in prostate cancer cells.

  8. miR (show MLXIP Antibodies)-92a, which is upregulated in cervical cancer, plays an oncogenic role in cervical cancer cell proliferation by directly targeting p21 and thus promoting cell cycle progression.

  9. KLF6 (show KLF6 Antibodies) acts as a tumor suppressor in CMM cells and miR (show MLXIP Antibodies)-4262 promotes the proliferation of CMM cells through KLF6 (show KLF6 Antibodies)-mediated EGFR (show EGFR Antibodies) inactivation and p21 upregulation.

  10. the combination of a proteasomal inhibitor and dimethylfumarate superinduces p21 expression in human dermal lymphendothelial cells

Cow (Bovine) Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. p21 expression reports on Bovine herpesvirus 4 replication and could represent a host cell defensive response to infection-associated cellular damage.

Mouse (Murine) Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. this study shows that p21 (show D4S234E Antibodies) is upregulated in T effector cells but not natural regulatory T cells after treatment with azacitidine, which protects from graft-versus-host Disease

  2. lincRNA-p21 (show D4S234E Antibodies) overexpression dramatically inhibited acetylation of H3 and H4 at the Thy-1 (show THY1 Antibodies) promoter and Thy-1 (show THY1 Antibodies) expression levels in HLF1 (show HLF Antibodies) cells. Finally, lincRNA-p21 (show D4S234E Antibodies) interference rescued LPS (show TLR4 Antibodies)-induced increase of lung and BAL collagen contents. LincRNA-p21 (show D4S234E Antibodies) could lead to pulmonary fibrosis in ARDS by inhibition of the expression of Thy-1 (show THY1 Antibodies).

  3. p21 (show D4S234E Antibodies) upregulation in hair follicle stem cells is associated with telogen retention in aged mice

  4. MiR-17-92 functions as a hepatocyte proliferation stimulator and acts in an estrogen-dependent manner. The loss of this miRNA results in increases in p21 (show D4S234E Antibodies) and Pten (show PTEN Antibodies) expression and therefore impairs liver regeneration in female mice.

  5. we observed that miR (show MLXIP Antibodies)-378 modulates the oscillation amplitudes of Cdkn1a in the control of cell cycle and Por (show POR Antibodies) in the regulation of oxidation reduction by forming partnership with different circadian transcription factors

  6. The findings define PRMT7 (show PRMT7 Antibodies) as a regulator of the DNMT3b (show DNMT3B Antibodies)/p21 (show D4S234E Antibodies) axis required to maintain muscle stem cell regenerative capacity.

  7. Dynamics of CDKN1A in single cells has been defined defined by an endogenous fluorescent tagging.

  8. Ablation of p21Cip1 in the Cdk4 (show CDK4 Antibodies) R24C background accelerates mesenchymal tumor development in mice.

  9. The lack of functional Waf1 is indispensable for maintaining self-renewal and pluripotency of embryonic stem cells.

  10. p27(Kip1 (show CDKN1B Antibodies)) and p21(Cip1) are insufficient for the proliferative inhibition of smooth muscle cells cultured in type 1 collagen.

CDKN1A Antigen Profile

Antigen Summary

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene.

Alternative names and synonyms associated with CDKN1A

  • cyclin-dependent kinase inhibitor 1A (p21, Cip1) (cdkn1a) antibody
  • cyclin-dependent kinase inhibitor 1 (cki1) antibody
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A) antibody
  • cyclin-dependent kinase inhibitor 1A (cdkn1a) antibody
  • cyclin-dependent kinase inhibitor 1A (LOC100348489) antibody
  • cyclin-dependent kinase inhibitor 1A (Cdkn1a) antibody
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1) (Cdkn1a) antibody
  • cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a) antibody
  • CAP20 antibody
  • CCND1 antibody
  • CDKI antibody
  • Cdkn1 antibody
  • CDKN1A antibody
  • CIP1 antibody
  • MDA-6 antibody
  • mda6 antibody
  • p16Xic2 antibody
  • P21 antibody
  • p21Cip1 antibody
  • p21WAF antibody
  • SDI1 antibody
  • si:ch1073-48m5.2 antibody
  • UV96 antibody
  • WAF1 antibody

Protein level used designations for CDKN1A

cyclin dependent kinase inhibitor p16Xic2 , cyclin-dependent kinase inhibitor 1 , cyclin D1 , cyclin-dependent kinase inhibitor 1A (p21, Cip1) , cip1 , p21 , waf1 , cyclin-dependent kinase inhibitor 1A , cyclin-dependent kinase inhibitor 1A (P21) , CDK-interacting protein 1 , CDK-interaction protein 1 , DNA synthesis inhibitor , melanoma differentiation associated protein 6 , wild-type p53-activated fragment 1 , p21/WAF1 , melanoma differentiation-associated protein , p21

492305 Xenopus laevis
606440 Zea mays
747442 Pan troglodytes
100038054 Xenopus (Silurana) tropicalis
100302083 Ovis aries
100151416 Danio rerio
100348489 Oryctolagus cuniculus
114851 Rattus norvegicus
1026 Homo sapiens
474890 Canis lupus familiaris
513497 Bos taurus
100152215 Sus scrofa
100720449 Cavia porcellus
493943 Felis catus
12575 Mus musculus
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