Browse our anti-FAS (FAS) Antibodies

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anti-Fas (TNF Receptor Superfamily, Member 6) Antibodies (FAS)
On are 756 Fas (TNF Receptor Superfamily, Member 6) (FAS) Antibodies from 40 different suppliers available. Additionally we are shipping FAS Kits (87) and FAS Proteins (65) and many more products for this protein. A total of 946 FAS products are currently listed.
A630082H08Rik, AI196731, ALPS1A, APO-1, APO1, APT1, CD95, FAS, FAS1, FASTM, lpr, TNFR6, TNFRSF6

All available anti-FAS Antibodies

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Top referenced anti-FAS Antibodies

  1. Human Monoclonal FAS Primary Antibody for IHC (fro), IF - ABIN1106610 : Vega, Jazirehi, Huerta-Yepez, Bonavida: Rituximab-induced inhibition of YY1 and Bcl-xL expression in Ramos non-Hodgkin's lymphoma cell line via inhibition of NF-kappa B activity: role of YY1 and Bcl-xL in Fas resistance and chemoresistance, respectively. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
    Show all 16 references for 1106610

  2. Human Monoclonal FAS Primary Antibody for FACS, IHC (p) - ABIN238438 : Nakamura, Kakinuma, Amada, Miyata, Taniguchi, Koda, Sato: Pyrazole derivatives as new potent and selective 20-hydroxy-5,8,11,14-eicosatetraenoic acid synthase inhibitors. in Bioorganic & medicinal chemistry 2004 (PubMed)
    Show all 6 references for 238438

  3. Human Polyclonal FAS Primary Antibody for EIA - ABIN358278 : Inaba, Glibetic, Buck, Ravindranath, Kaplan: Interferon-gamma sensitizes osteosarcoma cells to Fas-induced apoptosis by up-regulating Fas receptors and caspase-8. in Pediatric blood & cancer 2004 (PubMed)
    Show all 5 references for 358278

  4. Human Polyclonal FAS Primary Antibody for IF, WB - ABIN652469 : Feig, Tchikov, Schütze, Peter: Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling. in The EMBO journal 2007 (PubMed)
    Show all 3 references for 652469

  5. Human Monoclonal FAS Primary Antibody for IHC (p) - ABIN180528 : Sugihara, Saiki, Tsuji, Tsujimura, Nakata, Kubota, Kotake, Terada: Expression of Fas and Fas ligand in the testes and testicular germ cell tumors: an immunohistochemical study. in Anticancer research 1998 (PubMed)
    Show all 3 references for 180528

  6. Mouse (Murine) Polyclonal FAS Primary Antibody for IHC (fro), IF - ABIN1106611 : Desbarats, Birge, Mimouni-Rongy, Weinstein, Palerme, Newell: Fas engagement induces neurite growth through ERK activation and p35 upregulation. in Nature cell biology 2003 (PubMed)
    Show all 3 references for 1106611

  7. Human Polyclonal FAS Primary Antibody for WB - ABIN783308 : Hérold, Bismuth, Bensussan, Boumsell: Activation signals are delivered through two distinct epitopes of CD100, a unique 150 kDa human lymphocyte surface structure previously defined by BB18 mAb. in International immunology 1995 (PubMed)
    Show all 3 references for 783308

  8. Human Polyclonal FAS Primary Antibody for IHC (p) - ABIN115383 : Kondo, Yoshino, Nishiuchi, Sakuma, Nishizaki, Kayagaki, Yagita, Akagi: Expression of Fas ligand mRNA in germinal centres of the human tonsil. in The Journal of pathology 1997 (PubMed)
    Show all 3 references for 115383

  9. Human Monoclonal FAS Primary Antibody for FACS - ABIN1106623 : Jego, Robillard, Puthier, Amiot, Accard, Pineau, Harousseau, Bataille, Pellat-Deceunynck: Reactive plasmacytoses are expansions of plasmablasts retaining the capacity to differentiate into plasma cells. in Blood 1999 (PubMed)

  10. Mouse (Murine) Polyclonal FAS Primary Antibody for IF (p), IHC (p) - ABIN726395 : Zhou, Zheng, Yang, Zhang, Chen: Overexpression of CIRP may reduce testicular damage induced by cryptorchidism. in Clinical and investigative medicine. Médecine clinique et experimentale 2009 (PubMed)

More Antibodies against FAS Interaction Partners

Mouse (Murine) Fas (TNF Receptor Superfamily, Member 6) (FAS) interaction partners

  1. this study shows that CD95-mediated calcium signaling promotes Th17 cell trafficking to inflamed organs in lupus-prone mice

  2. accelerating effects of Tlr9 (show TLR9 Antibodies) deficiency

  3. K8/K18 (show KRT18 Antibodies)-dependent PKCdelta (show PKCd Antibodies)- and ASMase (show SMPD1 Antibodies)-mediated modulation of lipid raft size can explain the more prominent FasR-mediated signaling resulting from K8/K18 (show KRT18 Antibodies) loss.

  4. The present results suggest that Fas/S1P1 (show S1PR1 Antibodies) signaling via activation of NF-kappaB (show NFKB1 Antibodies) in osteoclast precursor cells is a key factor in the pathogenesis of rheumatoid arthritis in the temporomandibular joint.

  5. Data show that TCF1 (show HNF1A Antibodies) proteindeficiency relieved most manifestations of autoimmune lymphoproliferative syndrome (ALPS)-like phenotype, which were caused by Fas protein mutation in TCF1 (show HNF1A Antibodies)(-/-) lpr/lpr mice.

  6. Results indicate that the close interaction between Thy-1 (show THY1 Antibodies) and Fas in lipid rafts regulates fibroblast apoptosis, and decreased fibroblast apoptosis associated with myofibroblast accumulation in mice lacking Thy-1 (show THY1 Antibodies).

  7. genetic deletion of FASN totally suppresses hepatocarcinogenesis driven by AKT and AKT/c-Met protooncogenes in mice.

  8. Statistically significant increases in the expression of Fas and caspase-8 (show CASP8 Antibodies) were observed, along with other molecules involved in the extrinsic apoptotic pathway such as Dapk1 (show DAPK1 Antibodies), Traf3 (show TRAF3 Antibodies), Tnsf12, Tnfrsf1A (show TNFRSF1A Antibodies) and Ripk1 (show RIPK1 Antibodies).

  9. Data show that nuclear factor Y (NF-Y) binds to the inverted CCAAT element (ICE) in the Fatty acid synthase (Fasn (show FASN Antibodies)) promoter specifically in refeeding states.

  10. Taken together, these findings demonstrate that artesunate inhibits adipogenesis in 3T3-L1 preadipoytes through the reduced expression and/or phosphorylation levels of C/EBP-alpha (show CEBPA Antibodies), PPAR-gamma (show PPARG Antibodies), FAS, perilipin A (show PLIN1 Antibodies), and STAT-3 (show STAT3 Antibodies).

Rabbit Fas (TNF Receptor Superfamily, Member 6) (FAS) interaction partners

  1. Ligustrazine has notable protective effects on pulmonary ischemia/reperfusion injury inhibiting Fas/FasL (show FASL Antibodies) mRNA express in lung tissue and decreasing apoptosis.

Pig (Porcine) Fas (TNF Receptor Superfamily, Member 6) (FAS) interaction partners

  1. Fas was expressed on fetal pig pancreatic cells, both beta and non-beta cells, and the level of expression could be upregulated by exposure to interleukin 1beta

  2. The expression of FAS and FAS ligand (show FASL Antibodies) in splenic macrophages co-infected with porcine circovirus 2 and porcine reproductive and respiratory syndrome virus is reported

Cow (Bovine) Fas (TNF Receptor Superfamily, Member 6) (FAS) interaction partners

  1. Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES (show PTGES Antibodies)), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF (show TNF Antibodies)) and Fas were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.

  2. Results did not support that K8/K18 (show KRT18 Antibodies) filaments influence the expression of Fas on the surface of luteal cells.

  3. activation of the Fas pathway and presence of FSH (show BRD2 Antibodies) during in vitro maturation increased the incidence of apoptosis in cumulus cells

  4. demonstrated for the first time that normal ejaculated spermatozoa express Fas antigen (show FASL Antibodies); data showed that a large percentage of normal ejaculated spermatozoa of fertile bulls are immunocytochemically positive for Fas

Rhesus Monkey Fas (TNF Receptor Superfamily, Member 6) (FAS) interaction partners

  1. The present results may provide some insights to understand the role of Fas/FasL (show FASL Antibodies) in the spinal cord but not motor cortex with neuronal apoptosis and neuroplasticity in monkeys subjected to hemisection spinal cord injury.

Human Fas (TNF Receptor Superfamily, Member 6) (FAS) interaction partners

  1. These findings suggest that rs1800682, rs2234767, and rs763110 genotypes are not associated with the presence of HTLV-1-associated myelopathy/tropical spastic paraparesis, but that the FAS-670 AA genotype can promote higher proviral load values in HTLV-1-associated myelopathy/tropical spastic paraparesis patients.

  2. findings showed the variant allele and genotype of the FAS c.-671A>G polymorphism were significantly associated with increased risk of cervical cancer in Malaysian population, particularly those of Malay ethnicity; however, results of meta-analysis showed a lack of association between the polymorphism and cervical cancer risk

  3. Fas cell surface death receptor (FAS) was identified as an independent prognostic marker for recurrence free survival in breast cancer, with large variation in expression by receptor subtypes.

  4. data also demonstrated that the CD154 (show CD40LG Antibodies)-triggered inhibition of the Fas-mediated cell death response was dependent on a suppression of caspase-8 (show CASP8 Antibodies) cleavage, but independent of de novo protein synthesis or alterations in Fas expression on cell surface.

  5. We have identified two single nucleotide polymorphisms in two immune-related genes ( MBL (show MBL2 Antibodies)" and CD95) that have an association with severe and potentially life-threatening infection following doxorubicin and cyclophosphamide therapy for breast cancer

  6. With rs7901656 on the FAS gene as a paradigm, we show how allele specific transcription factor complex assembly and disruption by a causal variant contributes to disease and phenotypic diversity

  7. Increased TIM3 (show HAVCR2 Antibodies)+CD8 (show CD8A Antibodies)+T cells with lower perforin (show PRF1 Antibodies) and granzyme B (show Gzmb Antibodies) expression and higher CD95 expression in MDS (show PAFAH1B1 Antibodies) patients were observed.

  8. FAS c.-671AG genotype is not to be a risk factor in familial mediterranean fever (show MEFV Antibodies).

  9. functional inhibition of miR (show MLXIP Antibodies)-29c caused resistance to Fas-mediated apoptosis in lung fibroblasts.

  10. Most of the plasma cells of a paient with a heterozygous germline FAS mutation were Fas-deficient suggesting that Fas signaling plays a role also in the selection of germinal center B cells into the pool of long-lived plasma cells, similar to switched memory B cells.

FAS Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.

Alternative names and synonyms associated with FAS

  • Fas (TNF receptor superfamily member 6) (Fas) antibody
  • Fas (TNF receptor superfamily, member 6) (FAS) antibody
  • Fas cell surface death receptor (FAS) antibody
  • Fas cell surface death receptor (Fas) antibody
  • fatty acid synthase (Fasn) antibody
  • A630082H08Rik antibody
  • AI196731 antibody
  • ALPS1A antibody
  • APO-1 antibody
  • APO1 antibody
  • APT1 antibody
  • CD95 antibody
  • FAS antibody
  • FAS1 antibody
  • FASTM antibody
  • lpr antibody
  • TNFR6 antibody
  • TNFRSF6 antibody

Protein level used designations for FAS

FASLG receptor , Fas (TNF receptor superfamily member) , Fas antigen , apo-1 antigen , apoptosis-mediating surface antigen FAS , lymphoproliferation , tumor necrosis factor receptor superfamily member 6 , Fas receptor , apoptosis (APO-1) antigen 1 ( FAS ), member 6 , tumor necrosis factor receptor superfamily, member 6 , Fas receptor CD95 , APO-1 cell surface antigen , CD95 antigen , Delta Fas/APO-1/CD95 , FAS 827dupA , Fas (TNF receptor superfamily, member 6) , Fas AMA , TNF receptor superfamily member 6 , apoptosis antigen 1 , Fas antigen (ATP1) , Tumor necrosis factor receptor superfamily, member 6

14102 Mus musculus
100008609 Oryctolagus cuniculus
396826 Sus scrofa
282488 Bos taurus
574332 Macaca mulatta
355 Homo sapiens
246097 Rattus norvegicus
100726403 Cavia porcellus
14104 Mus musculus
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