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Browse our GTPase NRas Proteins (NRAS)

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GTPase NRas Proteins (NRAS)
On www.antibodies-online.com are 17 GTPase NRas (NRAS) Proteins from 6 different suppliers available. Additionally we are shipping GTPase NRas Antibodies (99) and GTPase NRas Kits (6) and many more products for this protein. A total of 127 GTPase NRas products are currently listed.
Synonyms:
ALPS4, AV095280, fj99a10, H-RAS, HRAS, N-RAS, NRAS, NRAS1, NS6, wu:fj99a10, zgc:100761, zras-b1
list all proteins Gene Name GeneID UniProt
Rat NRAS NRAS 24605 Q04970
NRAS 18176  
NRAS 4893 P01111

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GTPase NRas Proteins (NRAS) by Origin

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Top referenced GTPase NRas Proteins

  1. Human GTPase NRas Protein expressed in Escherichia coli (E. coli) - ABIN667768 : Brown, Marshall, Pennie, Hall: Mechanism of activation of an N-ras gene in the human fibrosarcoma cell line HT1080. in The EMBO journal 1984 (PubMed)
    Show all 2 references for ABIN667768

More Proteins for GTPase NRas Interaction Partners

Mouse (Murine) GTPase NRas (NRAS) interaction partners

  1. loss of one allele of Hras (show HRAS Proteins) increased the sensitivity of mice to this carcinogen, and this effect was further exacerbated by the loss of the second Hras (show HRAS Proteins) allele. However, loss of one or both alleles of Nras failed to alter tumor burden, either in the absence or presence of Hras (show HRAS Proteins), after exposure to urethane.

  2. Genetic inactivation of Ezh2 (show EZH2 Proteins) or Eed (show EED Proteins) cooperates with NRASQ61K in leukemogenesis.

  3. Data indicate that S-phase kinase-associated protein 2 (SKP2) cooperates with N-Ras and AKT proto-oncogenes to promote hepatocarcinogenesis in vivo.

  4. Activated NRAS and aberrant Wnt (show WNT2 Proteins) signaling conspire to drive congenital melanocytic nevus syndrome.

  5. a crucial role of RXRa in suppression of UVB-induced melanomas in the context of driver mutations such as activated CDK4(R24C/R24C) or oncogenic NRAS(Q61K) and altered expression of p53 and PTEN

  6. This work explains the curious predominance in human melanoma of mutations of codon 61 of NRAS over other oncogenic NRAS mutations. we show that physiologic expression of NRASQ61R, but not NRASG12D, drives melanoma formation.

  7. These data reveal the L. major-enhanced CD40-induced N-Ras activation as a novel immune evasion strategy and the potential for Ras isoform-targeted antileishmanial immunotherapy and immunoprophylaxis.

  8. NRAS expression is required for the proliferative advantage of human AML (show RUNX1 Proteins) cell lines in vitro and for the maintenance of mouse Nras-mutant AML (show RUNX1 Proteins) in vivo

  9. There was a nearly complete correspondence between the signaling pathways that were regulated by N-ras in immune cell types.

  10. Cbfbeta (show CBFB Proteins)-SMMHC (show MYH11 Proteins) and Nras(G12D) promote the survival of preleukemic myeloid progenitors primed for leukemia by activation of the MEK (show MDK Proteins)/ERK (show EPHB2 Proteins)/Bim (show BCL2L11 Proteins) axis, and define Nras(LSL-G12D); Cbfb (show CBFB Proteins)(56M) mice as a valuable genetic model for the study of AML (show RUNX1 Proteins) therapies.

Human GTPase NRas (NRAS) interaction partners

  1. The data revealed the presence of a partial tandem duplication of the MLL (show MLL Proteins) gene as the only detectable copy number change and 11 non-silent somatic mutations, including DNMT3A (show DNMT3A Proteins) R882H and NRAS G13D. All somatic lesions were present both at initial MDS (show PAFAH1B1 Proteins)/MPN (show PRSS27 Proteins)-U diagnosis and at AML (show RUNX1 Proteins) presentation at similar mutant allele frequencies.

  2. NRAS mutation is associated with CNS melanoma.

  3. NRAS mutation is associated with melanoma.

  4. Silencing VPS35 (show vps35 Proteins) increased N-Ras's association with cytoplasmic vesicles, diminished GTP (show AK3 Proteins) loading of Ras, and inhibited mitogen-activated protein kinase (show MAPK1 Proteins) signaling and growth of N-Ras-dependent melanoma cells.

  5. By using this model of curative-intent, margin-negative resection in patients at high risk of recurrence, the authors were able to establish a link between mutation location within the K/NRAS gene and the biology of metastatic colorectal cancer.

  6. review focuses on the genes, which are frequently mutated in various cancers and are known to be important in the advance and progression of colorectal cancer and melanoma, namely KRAS, NRAS and BRAF (show BRAF Proteins)

  7. Report KRAS, NRAS, PIK3CA, and BRAF mutational profile in poorly differentiated clusters of KRAS-mutated colon cancer may depend on tumor histology.

  8. SP174 immunohistochemistry allows sensitive detection of NRAS and KRAS Q61R mutants.

  9. multiregion analysis was performed in 60 spatially separated tumor areas according to the pathological tumor node metastasis (pTNM) staging and KRAS, NRAS and BRAF mutations were tested using pyrosequencing.these results suggest the need for multiple RAS testing in different parts of the same tumor and/or more sensitive techniques.

  10. that the presence of NRAS, PTEN and AKT1 (show AKT1 Proteins) gene mutations may have an influence on the occurrence of CNS metastases in patients with SqCC

Zebrafish GTPase NRas (NRAS) interaction partners

  1. Although oncogenic NRAS expression alone was found to be insufficient to promote tumor formation, loss of functional p53 (show TP53 Proteins) was found to collaborate with NRAS expression in the genesis of melanoma.

GTPase NRas (NRAS) Protein Profile

Protein Summary

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Alternative names and synonyms associated with GTPase NRas (NRAS)

  • GTPase NRas (Tsp_01117)
  • African clawed frog N-ras (n-ras)
  • neuroblastoma ras oncogene (Nras)
  • neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS)
  • neuroblastoma RAS viral (v-ras) oncogene homolog (nras)
  • ALPS4 protein
  • AV095280 protein
  • fj99a10 protein
  • H-RAS protein
  • HRAS protein
  • N-RAS protein
  • NRAS protein
  • NRAS1 protein
  • NS6 protein
  • wu:fj99a10 protein
  • zgc:100761 protein
  • zras-b1 protein

Protein level used designations for GTPase NRas Proteins (NRAS)

GTPase NRas , transforming protein N-Ras , neuroblastoma RAS viral (v-ras) oncogene homolog , N-ras oncogene , p21 protein , N-ras protein part 4 , v-ras neuroblastoma RAS viral oncogene homolog , ras p21 , N-ras oncogene p21 , etID18709.8 , neuroblastoma RAS viral oncogene-like protein , neuroblastoma ras oncogene , v-Ha-ras Harvey rat sarcoma viral oncogene homolog

GENE ID SPECIES
10905151 Trichinella spiralis
399446 Xenopus laevis
24605 Rattus norvegicus
18176 Mus musculus
100135584 Cavia porcellus
4893 Homo sapiens
403872 Canis lupus familiaris
30380 Danio rerio
419885 Gallus gallus
100739349 Sus scrofa
506322 Bos taurus
100174317 Pongo abelii
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