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Browse our GTPase NRas Proteins (NRAS)

Full name:
GTPase NRas Proteins (NRAS)
On www.antibodies-online.com are 18 GTPase NRas (NRAS) Proteins from 7 different suppliers available. Additionally we are shipping GTPase NRas Antibodies (71) and GTPase NRas Kits (6) and many more products for this protein. A total of 101 GTPase NRas products are currently listed.
Synonyms:
ALPS4, AV095280, fj99a10, H-RAS, HRAS, N-RAS, NRAS, NRAS1, NS6, wu:fj99a10, zgc:100761, zras-b1
list all proteins Gene Name GeneID UniProt
Rat NRAS NRAS 24605 Q04970
NRAS 18176  
NRAS 4893 P01111

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GTPase NRas Proteins (NRAS) by Origin

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Top referenced GTPase NRas Proteins

  1. Human GTPase NRas Protein expressed in Escherichia coli (E. coli) - ABIN667768 : Brown, Marshall, Pennie, Hall: Mechanism of activation of an N-ras gene in the human fibrosarcoma cell line HT1080. in The EMBO journal 1984 (PubMed)
    Show all 2 references for ABIN667768

More Proteins for GTPase NRas Interaction Partners

Mouse (Murine) GTPase NRas (NRAS) interaction partners

  1. Data indicate that S-phase kinase-associated protein 2 (SKP2) cooperates with N-Ras and AKT proto-oncogenes to promote hepatocarcinogenesis in vivo.

  2. Activated NRAS and aberrant Wnt (show WNT2 Proteins) signaling conspire to drive congenital melanocytic nevus syndrome.

  3. a crucial role of RXRa in suppression of UVB-induced melanomas in the context of driver mutations such as activated CDK4(R24C/R24C) or oncogenic NRAS(Q61K) and altered expression of p53 and PTEN

  4. This work explains the curious predominance in human melanoma of mutations of codon 61 of NRAS over other oncogenic NRAS mutations. we show that physiologic expression of NRASQ61R, but not NRASG12D, drives melanoma formation.

  5. These data reveal the L. major-enhanced CD40-induced N-Ras activation as a novel immune evasion strategy and the potential for Ras isoform-targeted antileishmanial immunotherapy and immunoprophylaxis.

  6. NRAS expression is required for the proliferative advantage of human AML (show RUNX1 Proteins) cell lines in vitro and for the maintenance of mouse Nras-mutant AML (show RUNX1 Proteins) in vivo

  7. There was a nearly complete correspondence between the signaling pathways that were regulated by N-ras in immune cell types.

  8. Cbfbeta (show CBFB Proteins)-SMMHC (show MYH11 Proteins) and Nras(G12D) promote the survival of preleukemic myeloid progenitors primed for leukemia by activation of the MEK (show MDK Proteins)/ERK (show EPHB2 Proteins)/Bim (show BCL2L11 Proteins) axis, and define Nras(LSL-G12D); Cbfb (show CBFB Proteins)(56M) mice as a valuable genetic model for the study of AML (show RUNX1 Proteins) therapies.

  9. regulation of Nf1 exon 23a inclusion serves as a mechanism for providing appropriate levels of Ras signaling.

  10. These observations provide genetic evidence for an essential role of Ras proteins in the control of keratinocyte and epidermal proliferation.

Human GTPase NRas (NRAS) interaction partners

  1. Levels of BRAF(mutant) and NRAS(mutant) ctDNA were determined using droplet digital PCR (ddPCR) assays. Among patients with samples available prior to treatment initiation ctDNA and LDH levels were elevated in 12/15 (80%) and 6/20 (30%) (p = 0.006) patients respectively

  2. ABHD17 catalytic activity is required for N-Ras depalmitoylation and re-localization to internal cellular membranes.

  3. let-7 is a tumor suppressor that negatively regulates RAS, also in Ewing Sarcoma, and HIF-1alpha (show HIF1A Proteins) may contribute to the aggressive metastatic behavior of Ewing Sarcoma

  4. MC1R (show MSHR Proteins) status is associated with BRAF (show BRAF Proteins)(V600E), BRAF (show BRAF Proteins)(V600K), and NRAS mutations in cutaneous melanomas

  5. BRAF (show BRAF Proteins), NRAS and KRAS gene mutations in plasma cell dyscrasias may have a role MEK (show MAP2K1 Proteins)-ERK (show EPHB2 Proteins) pathway activation

  6. Studies indicate that KRAS and NRAS mutations are currently recognized as the best predictive factors for primary resistance to anti-EGFR (show EGFR Proteins) monoclonal antibodies.

  7. Data suggest that Src (show SRC Proteins) kinases inhibitors may act with different mechanisms in non-small cell lung cancer (NSCLC) depending on EGF receptor (EGFR (show EGFR Proteins))/Ras protein (Ras) mutational profile.

  8. Data show that 11/105 patients failed all molecular analysis: no mutations in oncogenes EGFR, KRAS and NRAS were detected, and no ALK gene rearrangements or MET gene amplifications were identified.

  9. somatic mosaicism for a mutation accounts for disparate phenotypes in RAS-associated leukoproliferative disease

  10. analysis of HRAS (show HRAS Proteins), KRAS and NRAS expression in colorectal tumor cells

Zebrafish GTPase NRas (NRAS) interaction partners

  1. Although oncogenic NRAS expression alone was found to be insufficient to promote tumor formation, loss of functional p53 (show TP53 Proteins) was found to collaborate with NRAS expression in the genesis of melanoma.

GTPase NRas (NRAS) Protein Profile

Protein Summary

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Alternative names and synonyms associated with GTPase NRas (NRAS)

  • GTPase NRas (Tsp_01117)
  • African clawed frog N-ras (n-ras)
  • neuroblastoma ras oncogene (Nras)
  • neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS)
  • neuroblastoma RAS viral (v-ras) oncogene homolog (nras)
  • ALPS4 protein
  • AV095280 protein
  • fj99a10 protein
  • H-RAS protein
  • HRAS protein
  • N-RAS protein
  • NRAS protein
  • NRAS1 protein
  • NS6 protein
  • wu:fj99a10 protein
  • zgc:100761 protein
  • zras-b1 protein

Protein level used designations for GTPase NRas Proteins (NRAS)

GTPase NRas , transforming protein N-Ras , neuroblastoma RAS viral (v-ras) oncogene homolog , N-ras oncogene , p21 protein , N-ras protein part 4 , v-ras neuroblastoma RAS viral oncogene homolog , ras p21 , N-ras oncogene p21 , etID18709.8 , neuroblastoma RAS viral oncogene-like protein , neuroblastoma ras oncogene , v-Ha-ras Harvey rat sarcoma viral oncogene homolog

GENE ID SPECIES
10905151 Trichinella spiralis
399446 Xenopus laevis
24605 Rattus norvegicus
18176 Mus musculus
100135584 Cavia porcellus
4893 Homo sapiens
403872 Canis lupus familiaris
30380 Danio rerio
419885 Gallus gallus
100739349 Sus scrofa
506322 Bos taurus
100174317 Pongo abelii
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