Browse our TWIST1 Proteins (TWIST1)

Full name:
Twist Homolog 1 (Drosophila) Proteins (TWIST1)
On www.antibodies-online.com are 13 Twist Homolog 1 (Drosophila) (TWIST1) Proteins from 4 different suppliers available. Additionally we are shipping TWIST1 Antibodies (159) and TWIST1 Kits (10) and many more products for this protein. A total of 196 TWIST1 products are currently listed.
Synonyms:
AA960487, ACS3, bHLHa38, BPES2, BPES3, CRS1, cTwist, M-Twist, MGC69439, Pde, pdt, SCS, Ska10, Ska, Twist, twist-1, twist1, Twist1b, wu:fd04c01, X-twi, Xtwi, Xtwist, zgc:101115
list all proteins Gene Name GeneID UniProt
TWIST1 7291 Q15672
Mouse TWIST1 TWIST1 22160 P26687
Rat TWIST1 TWIST1 85489  

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TWIST1 Proteins (TWIST1) by Origin

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Cow (Bovine) Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. Frame-shift mutation in TWIST1 is associated with type 2 scurs syndrome.

Xenopus laevis Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. Interaction with Snail1/2, and Twist function more generally, is regulated by GSK-3-beta-mediated phosphorylation of conserved sites in the WR domain.

Human Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. SPZ1 (show SPZ1 Proteins) promotes epithelial-mesenchymal transition (EMT (show ITK Proteins))transition by trans-activating the gene of TWIST1. A clinical analysis showed a marker association of SPZ1 (show SPZ1 Proteins) and TWIST1 with induction of tumorigenesis in HCC (show FAM126A Proteins) patients.

  2. TrpC5 (show TRPC5 Proteins) induces the epithelial-mesenchymal transition through the HIF-1alpha (show HIF1A Proteins)-Twist signaling pathway to promote tumor metastasis in colon cancer.

  3. molecular and cellular processes that regulate dural Cerebral vein development in mammals and describe venous malformations in humans with craniosynostosis and TWIST1 mutations that are recapitulated in mouse models, are reported.

  4. this study shows that low Twist1 expression in idiopathic pulmonary fibrosis patients is associated with dysregulation of T cells, and that Twist1 may regulate inflammation (show CXCL12 Proteins)in fibrotic lung injury

  5. High TWIST1 expression is associated with breast cancer invasion and metastasis.

  6. Results found concomitant overexpression of MAGEA4 (show MAGEA4 Proteins) and TWIST1 in esophageal squamous cell carcinoma (ESCC). Also, it showed a correlation between MAGEA4 (show MAGEA4 Proteins) and TWIST1 expression, which was found as indirect binding of TWIST1 to the E-boxes in the MAGEA4 (show MAGEA4 Proteins) promoter revealing transcriptional upregulation of MAGEA4 (show MAGEA4 Proteins) by TWIST1.

  7. RNF8 (show RNF8 Proteins)-promoted Twist ubiquitination is required for Twist localization to the nucleus for subsequent epithelial-mesenchymal transition and cancer stem cells functions, thereby conferring chemoresistance.

  8. Twist1 appears to require both palladin (show PALLD Proteins) and collagen alpha1(VI) as downstream effectors for its prometastatic effects, which could be future therapeutic targets in cancer metastasis.

  9. Clinically, Twist transcript and protein expression was higher in areca quid chewing-associated Oral submucous fibrosis (OSF (show OSTF1 Proteins)) tissues than in normal oral mucosa tissues. This evidence suggests that upregulation of Twist might be involved in the pathogenesis of areca quid-associated OSF (show OSTF1 Proteins) through dysregulation of myofibroblast activity.

  10. This is the first study that links Twist1 in a feedback loop with its activating kinase, which indicates that concurrent inhibition of AURKA (show AURKA Proteins) and Twist1 will be synergistic in inhibiting pancreatic tumorigenesis and metastasis.

Mouse (Murine) Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. molecular and cellular processes that regulate dural Cerebral vein development in mammals and describe venous malformations in humans with craniosynostosis and TWIST1 mutations that are recapitulated in mouse models, are reported.

  2. Methyltransferase G9A (show EHMT2 Proteins) Regulates Osteogenesis via Twist Gene Repression in mice.

  3. this study shows that loss of Twist1 in collagen-producing cells leads to increased bleomycin-induced pulmonary fibrosis, which is mediated by increased expression of CXCL12 (show CXCL12 Proteins)

  4. RNF8 (show RNF8 Proteins)-promoted Twist ubiquitination is required for Twist localization to the nucleus for subsequent epithelial-mesenchymal transition and cancer stem cells functions, thereby conferring chemoresistance.

  5. These results indicate that Twist1 Ser42 phosphorylation contributes to the pathogenesis of bleomycin-induced pulmonary fibrosis through angiopoietin-Tie2 (show TEK Proteins) signaling.

  6. the mesenchymal properties of the cranial mesoderm are likely to be regulated by a network of TWIST1 targets that influences the extracellular matrix and cell-matrix interactions, and collectively they are required for the morphogenesis of the craniofacial structures.

  7. TWIST1 expression promotes developmental angiogenesis by inducing endothelial cell proliferation and migration.

  8. There was a possible regulatory link between Twist 1 and PPARgamma (show PPARG Proteins) in 3T3-L1 mature adipocytes. This regulatory link enhanced the regulation of PPARgamma (show PPARG Proteins) and may be a functional mechanism of Twist 1 regulation of adipocyte physiology and pathology

  9. ur study revealed the dynamic Twist localization within the early stage of embryo. The results are discussed in terms of potential roles of Twist1 in the processes of lineage segregation, hatching, and implantation in post-compaction embryos and in blastocysts.

  10. findings demonstrate that Twist-1, which maintains BMSC at an immature state, endows them with an increased capacity for supporting hematopoiesis via direct activation of CXCL12 (show CXCL12 Proteins) gene expression.

Zebrafish Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. the ventral migration of Cranial neural crest cells (CNCCs) away from a source of Bmps in the dorsal ectoderm promotes ectomesenchyme development by relieving Id2a-dependent repression of Twist1 function.

  2. twist1a and twist1b control skeletal development and dorsoventral patterning by regulating runx2b in zebrafish

  3. These observations are consistent with a role for twist1 in craniofacial, vertebral, and early renal development.

TWIST1 Protein Profile

Protein Summary

Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue\; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.

Alternative names and synonyms associated with TWIST1

  • twist homolog 1 (Drosophila) (TWIST1)
  • twist homolog 1 (twist1)
  • twist basic helix-loop-helix transcription factor 1 (twist1-a)
  • twist basic helix-loop-helix transcription factor 1 (TWIST1)
  • twist basic helix-loop-helix transcription factor 1 (Twist1)
  • twist1a (twist1a)
  • AA960487 protein
  • ACS3 protein
  • bHLHa38 protein
  • BPES2 protein
  • BPES3 protein
  • CRS1 protein
  • cTwist protein
  • M-Twist protein
  • MGC69439 protein
  • Pde protein
  • pdt protein
  • SCS protein
  • Ska10 protein
  • Ska protein
  • Twist protein
  • twist-1 protein
  • twist1 protein
  • Twist1b protein
  • wu:fd04c01 protein
  • X-twi protein
  • Xtwi protein
  • Xtwist protein
  • zgc:101115 protein

Protein level used designations for TWIST1

twist homolog 1 , twist transcription factor , twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) , hypothetical protein , twist-like protein , twist-related protein 1 , T18 , X-twist , twist-related protein , B-HLH DNA binding protein , H-twist , TWIST homolog of drosophila , class A basic helix-loop-helix protein 38 , Pluridigite , Skam10Jus , charlie chaplin , polydactyly EMS , twist gene homolog 1 , twist 1 , twist homolog 1 (Drosophila)

GENE ID SPECIES
100431892 Pongo abelii
395054 Xenopus (Silurana) tropicalis
574278 Macaca mulatta
782170 Bos taurus
378698 Xenopus laevis
7291 Homo sapiens
22160 Mus musculus
85489 Rattus norvegicus
395491 Gallus gallus
609156 Canis lupus familiaris
450135 Pan troglodytes
30175 Danio rerio
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