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Browse our TWIST1 Proteins (TWIST1)

Full name:
Twist Homolog 1 (Drosophila) Proteins (TWIST1)
On are 13 Twist Homolog 1 (Drosophila) (TWIST1) Proteins from 4 different suppliers available. Additionally we are shipping TWIST1 Antibodies (123) and TWIST1 Kits (10) and many more products for this protein. A total of 160 TWIST1 products are currently listed.
AA960487, ACS3, bHLHa38, BPES2, BPES3, CRS1, cTwist, M-Twist, MGC69439, Pde, pdt, SCS, Ska10, Ska, Twist, twist-1, twist1, Twist1b, wu:fd04c01, X-twi, Xtwi, Xtwist, zgc:101115
list all proteins Gene Name GeneID UniProt
TWIST1 7291 Q15672
Mouse TWIST1 TWIST1 22160 P26687
Rat TWIST1 TWIST1 85489  

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TWIST1 Proteins (TWIST1) by Origin

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Cow (Bovine) Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. Frame-shift mutation in TWIST1 is associated with type 2 scurs syndrome.

Xenopus laevis Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. Interaction with Snail1/2, and Twist function more generally, is regulated by GSK-3-beta-mediated phosphorylation of conserved sites in the WR domain.

Human Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. These results indicate that Twist1 Ser42 phosphorylation contributes to the pathogenesis of bleomycin-induced pulmonary fibrosis through angiopoietin-Tie2 (show TEK Proteins) signaling.

  2. the epithelial-mesenchymal transition-related transcription factor Twist1 cooperates with Slug (show SNAI2 Proteins) to regulate EMT (show ITK Proteins) upon H2A.X (show H2AFX Proteins) Loss.

  3. Downregulation of CXC chemokine (show CXCL12 Proteins) ligand 11 can inhibit tumor angiogenesis, suggesting that anti-CXC chemokine (show CXCL12 Proteins) ligand 11 therapy may offer an alternative treatment strategy for TWIST1-positive ovarian cancer

  4. The data identify TWIST1 as a central pro-fibrotic factor in systemic sclerosis, which facilitates fibroblast activation by amplifying TGFbeta (show TGFB1 Proteins) signalling.

  5. ETS2 (show ETS2 Proteins) and Twist1 promote invasiveness of Helicobacter pylori-infected gastric cancer cells by inducing Siah2 (show SIAH2 Proteins)

  6. CD44, ALDH1 and Twist1 were significantly overexpressed in involved ALN. The serum levels of CA153 in those patients were clearly increased and the survival rates decreased, which suggested that a combination of Twist1 in ALN and CA153 may function as an indicator for the prognosis of patients with breast cancer.

  7. TWIST1-E protein heterodimeric complexes may thus constitute the main active forms of TWIST1 with regard to senescence inhibition over the time course of breast tumorigenesis.

  8. nuclear TWIST1 expression was an independent predictor of a poorer prognosis in metastatic melanoma.

  9. HMGA2 regulates the Epithelial-mesenchymal transition of gastric cancer cells and the acquisition of tumor stem cell properties through direct regulation of the downstream target gene TWIST1.

  10. overexpression of miR (show MLXIP Proteins)-10b results from high levels of TWIST-1 and may induce a decrease of E-cadherin (show CDH1 Proteins) membranous protein levels, thus contributing to the acquisition of metastatic phenotypes in colorectal cancer.

Mouse (Murine) Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. These results indicate that Twist1 Ser42 phosphorylation contributes to the pathogenesis of bleomycin-induced pulmonary fibrosis through angiopoietin-Tie2 (show TEK Proteins) signaling.

  2. the mesenchymal properties of the cranial mesoderm are likely to be regulated by a network of TWIST1 targets that influences the extracellular matrix and cell-matrix interactions, and collectively they are required for the morphogenesis of the craniofacial structures.

  3. TWIST1 expression promotes developmental angiogenesis by inducing endothelial cell proliferation and migration.

  4. There was a possible regulatory link between Twist 1 and PPARgamma (show PPARG Proteins) in 3T3-L1 mature adipocytes. This regulatory link enhanced the regulation of PPARgamma (show PPARG Proteins) and may be a functional mechanism of Twist 1 regulation of adipocyte physiology and pathology

  5. ur study revealed the dynamic Twist localization within the early stage of embryo. The results are discussed in terms of potential roles of Twist1 in the processes of lineage segregation, hatching, and implantation in post-compaction embryos and in blastocysts.

  6. findings demonstrate that Twist-1, which maintains BMSC at an immature state, endows them with an increased capacity for supporting hematopoiesis via direct activation of CXCL12 (show CXCL12 Proteins) gene expression.

  7. Twist1, a target of canonical Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling, also functions to maintain Wnt (show WNT2 Proteins) responsiveness and is a key effector for cranial bone fate selection and dermal condensation.

  8. Findings indicate that Twist1 has a novel role in epithelial carcinogenesis by regulating proliferation of keratinocytes, including keratinocyte stem cells during tumor promotion.

  9. Data show that administration of MVA (show MYO5A Proteins)-TWIST/TRICOM vaccine induces Twist transcription factor-specific T-cell responses.

  10. TLR4 (show TLR4 Proteins) signaling via NANOG (show NANOG Proteins) cooperates with STAT3 (show STAT3 Proteins) to activate Twist1 and promote formation of tumor-initiating stem-like cells in livers of mice.

Zebrafish Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. the ventral migration of Cranial neural crest cells (CNCCs) away from a source of Bmps in the dorsal ectoderm promotes ectomesenchyme development by relieving Id2a-dependent repression of Twist1 function.

  2. twist1a and twist1b control skeletal development and dorsoventral patterning by regulating runx2b in zebrafish

  3. These observations are consistent with a role for twist1 in craniofacial, vertebral, and early renal development.

TWIST1 Protein Profile

Protein Summary

Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue\; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.

Alternative names and synonyms associated with TWIST1

  • twist homolog 1 (Drosophila) (TWIST1)
  • twist homolog 1 (twist1)
  • twist basic helix-loop-helix transcription factor 1 (twist1-a)
  • twist basic helix-loop-helix transcription factor 1 (TWIST1)
  • twist basic helix-loop-helix transcription factor 1 (Twist1)
  • twist1a (twist1a)
  • AA960487 protein
  • ACS3 protein
  • bHLHa38 protein
  • BPES2 protein
  • BPES3 protein
  • CRS1 protein
  • cTwist protein
  • M-Twist protein
  • MGC69439 protein
  • Pde protein
  • pdt protein
  • SCS protein
  • Ska10 protein
  • Ska protein
  • Twist protein
  • twist-1 protein
  • twist1 protein
  • Twist1b protein
  • wu:fd04c01 protein
  • X-twi protein
  • Xtwi protein
  • Xtwist protein
  • zgc:101115 protein

Protein level used designations for TWIST1

twist homolog 1 , twist transcription factor , twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) , hypothetical protein , twist-like protein , twist-related protein 1 , T18 , X-twist , twist-related protein , B-HLH DNA binding protein , H-twist , TWIST homolog of drosophila , class A basic helix-loop-helix protein 38 , Pluridigite , Skam10Jus , charlie chaplin , polydactyly EMS , twist gene homolog 1 , twist 1 , twist homolog 1 (Drosophila)

100431892 Pongo abelii
395054 Xenopus (Silurana) tropicalis
574278 Macaca mulatta
782170 Bos taurus
378698 Xenopus laevis
7291 Homo sapiens
22160 Mus musculus
85489 Rattus norvegicus
395491 Gallus gallus
609156 Canis lupus familiaris
450135 Pan troglodytes
30175 Danio rerio
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