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Browse our TWIST1 Proteins (TWIST1)

Full name:
Twist Homolog 1 (Drosophila) Proteins (TWIST1)
On are 13 Twist Homolog 1 (Drosophila) (TWIST1) Proteins from 4 different suppliers available. Additionally we are shipping TWIST1 Antibodies (97) and TWIST1 Kits (7) and many more products for this protein. A total of 131 TWIST1 products are currently listed.
AA960487, ACS3, bHLHa38, BPES2, BPES3, CRS1, cTwist, M-Twist, MGC69439, Pde, pdt, SCS, Ska10, Ska, Twist, twist-1, twist1, Twist1b, wu:fd04c01, X-twi, Xtwi, Xtwist, zgc:101115
list all proteins Gene Name GeneID UniProt
TWIST1 7291 Q15672
Mouse TWIST1 TWIST1 22160 P26687
Rat TWIST1 TWIST1 85489  

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TWIST1 Proteins (TWIST1) by Origin

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Cow (Bovine) Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. Frame-shift mutation in TWIST1 is associated with type 2 scurs syndrome.

Xenopus laevis Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. Interaction with Snail1/2, and Twist function more generally, is regulated by GSK-3-beta-mediated phosphorylation of conserved sites in the WR domain.

Human Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. Twist-ITGB1 (show ITGB1 Proteins)-FAK (show PTK2 Proteins)/ILK (show ILK Proteins) pathway and their downstream signaling network dictate the Twist-induced EMT (show ITK Proteins) process in human mammary epithelial cells and breast cancer cells

  2. Findings suggest that miR (show MLXIP Proteins)-548c directly downregulates Twist, and provide a novel mechanism for Twist upregulation in both endometrial and ovarian cancers.

  3. Study found that upregulated Twist1 increased Bmi1 (show BMI1 Proteins) expression in acute myeloid leukemia (show BCL11A Proteins) (AML (show RUNX1 Proteins)) and endued leukemic cells a higher proliferative potential and increased resistance to apoptosis. In primary AML (show RUNX1 Proteins) samples, there was strong positive correlation between the expression levels of Twist1 and Bmi1 (show BMI1 Proteins).

  4. TWIST1 promoter hypermethylation is associated with Colorectal Cancer.

  5. Twist1 is correlated with p-4E-BP1 (show EIF4EBP1 Proteins) in predicting the prognostic outcome of NSCLC.

  6. TWIST1 has a potential causative effect on the development of ventricular septal defect.

  7. expression of ZEB1 and TWIST1, which are master regulators of tumor metastasis. Our study first indicates that miR (show MLXIP Proteins)-1271 functions as a suppressor in regulating of pancreatic cancer EMT (show ITK Proteins) by targeting ZEB1 and TWIST1.

  8. Activation of the miR (show MLXIP Proteins)-373-TXNIP (show TXNIP Proteins)-HIF1alpha (show HIF1A Proteins)-TWIST signaling axis is correlated with a worse outcome in patients with breast cancer.

  9. findings not only pinpoint that Twist1 mediates the modulatory function of PAQR3 (show PAQR3 Proteins) on EMT (show ITK Proteins) and metastasis but also suggest that targeting Twist1 is a promising strategy to control metastasis of tumors with downregulation of PAQR3 (show PAQR3 Proteins)

  10. Twist promotes reprogramming of glucose metabolism in MCF10A-Twist cells and Twist-positive breast cancer cells via activation of the beta1-integrin/FAK (show PTK2 Proteins)/PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) pathway and inhibition of the p53 (show TP53 Proteins) pathway.

Mouse (Murine) Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. Findings indicate that Twist1 has a novel role in epithelial carcinogenesis by regulating proliferation of keratinocytes, including keratinocyte stem cells during tumor promotion.

  2. Data show that administration of MVA (show MYO5A Proteins)-TWIST/TRICOM vaccine induces Twist transcription factor-specific T-cell responses.

  3. TLR4 (show TLR4 Proteins) signaling via NANOG (show NANOG Proteins) cooperates with STAT3 (show STAT3 Proteins) to activate Twist1 and promote formation of tumor-initiating stem-like cells in livers of mice.

  4. studies suggested that the Twist1 transcription in GC cells might be regulated through potential cooperation of DNA methylation (show HELLS Proteins), histone modification in complex with Sp1 (show SP1 Proteins) binding to CpG-rich regions within the exon 1 region

  5. Study shows that Twist1 plays a pivotal role in the TNF (show TNF Proteins) mediated suppression of E-box dependent transactivation of Period genes and Dbp (show GC Proteins). Thereby Twist1 may provide a link between the immune system and the circadian timing system.

  6. Hypoxia models showed the mechanism by which hypoxia promoted Twist1 and Bmi1 (show BMI1 Proteins) expression and led to vasculogenic mimicry formation.

  7. Twist1 plays crucial roles in regulating tooth development and it may exert its functions through the FGF signaling pathway

  8. Overexpression and cooperation of Bcl-2 (show BCL2 Proteins) and Twist1 is associated with epithelial-mesenchymal transition and vasculogenic mimicry formation in hepatocellular carcinoma.

  9. These results indicate that tamoxifen can significantly accelerate Twist1 degradation to suppress cancer cell invasion and metastasis, regardless of the estrogen receptor (show ESR1 Proteins) status.

  10. overexpression of Id2 in primary alveolar epithelial cells promotes proliferation by inhibiting a retinoblastoma protein/c-Abl interaction leading to greater c-Abl activity.

Zebrafish Twist Homolog 1 (Drosophila) (TWIST1) interaction partners

  1. the ventral migration of Cranial neural crest cells (CNCCs) away from a source of Bmps in the dorsal ectoderm promotes ectomesenchyme development by relieving Id2a-dependent repression of Twist1 function.

  2. twist1a and twist1b control skeletal development and dorsoventral patterning by regulating runx2b in zebrafish

  3. These observations are consistent with a role for twist1 in craniofacial, vertebral, and early renal development.

TWIST1 Protein Profile

Protein Summary

Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue\; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.

Alternative names and synonyms associated with TWIST1

  • twist homolog 1 (Drosophila) (TWIST1)
  • twist homolog 1 (twist1)
  • twist basic helix-loop-helix transcription factor 1 (twist1-a)
  • twist basic helix-loop-helix transcription factor 1 (TWIST1)
  • twist basic helix-loop-helix transcription factor 1 (Twist1)
  • twist1a (twist1a)
  • AA960487 protein
  • ACS3 protein
  • bHLHa38 protein
  • BPES2 protein
  • BPES3 protein
  • CRS1 protein
  • cTwist protein
  • M-Twist protein
  • MGC69439 protein
  • Pde protein
  • pdt protein
  • SCS protein
  • Ska10 protein
  • Ska protein
  • Twist protein
  • twist-1 protein
  • twist1 protein
  • Twist1b protein
  • wu:fd04c01 protein
  • X-twi protein
  • Xtwi protein
  • Xtwist protein
  • zgc:101115 protein

Protein level used designations for TWIST1

twist homolog 1 , twist transcription factor , twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) , hypothetical protein , twist-like protein , twist-related protein 1 , T18 , X-twist , twist-related protein , B-HLH DNA binding protein , H-twist , TWIST homolog of drosophila , class A basic helix-loop-helix protein 38 , Pluridigite , Skam10Jus , charlie chaplin , polydactyly EMS , twist gene homolog 1 , twist 1 , twist homolog 1 (Drosophila)

100431892 Pongo abelii
395054 Xenopus (Silurana) tropicalis
574278 Macaca mulatta
782170 Bos taurus
378698 Xenopus laevis
7291 Homo sapiens
22160 Mus musculus
85489 Rattus norvegicus
395491 Gallus gallus
609156 Canis lupus familiaris
450135 Pan troglodytes
30175 Danio rerio
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