Browse our KLF4 Proteins (KLF4)

On are 14 Kruppel-Like Factor 4 (Gut) (KLF4) Proteins from 8 different suppliers available. Additionally we are shipping KLF4 Antibodies (286) and KLF4 Kits (7) and many more products for this protein. A total of 323 KLF4 products are currently listed.
biklf, biklf-A, EZF, Gklf, KLF4, Zie
list all proteins Gene Name GeneID UniProt
KLF4 9314 O43474
KLF4 16600 Q60793
Rat KLF4 KLF4 114505  

KLF4 Proteins (KLF4) by Origin

More Proteins for KLF4 Interaction Partners

Zebrafish Kruppel-Like Factor 4 (Gut) (KLF4) interaction partners

  1. zebrafih Klf4a is essential for the repression of intestinal cell proliferation

  2. Proper heart valve formation in zebrafish critically depends on protein kinase D2 (show PKD2 Proteins)-histone deacetylase 5 (show HDAC5 Proteins)-Kruppel-like factor signaling.

Human Kruppel-Like Factor 4 (Gut) (KLF4) interaction partners

  1. KLF4 transactivates Ch25h and LXR, thereby promoting the synergistic effects between ECs and macrophages to protect against atherosclerosis susceptibility.

  2. findings evidence a positive correlation between SIRT1 (show SIRT1 Proteins) and BCL6 (show BCL6 Proteins) expression increase in follicular lymphomas (FL) . SIRT1 (show SIRT1 Proteins) methylation decreases in FL and diffuse large-B cell lymphomas (DLBCL)and this parallels the increase of KLF4, DAPK1 (show DAPK1 Proteins) and SPG20 (show SPG20 Proteins) methylation

  3. the use of KLF4 as a diagnostic and therapeutic target in cancer requires careful consideration of context.

  4. KLF4 suppresses oncogenic TGF-beta (show TGFB1 Proteins) signaling by activation of Smad7 (show SMAD7 Proteins) transcription, and loss of KLF4 expression in primary hepatocellular carcinoma may contribute to activation of oncogenic TGF-beta (show TGFB1 Proteins) signaling and subsequent tumor progression.

  5. loss of KLF4 and expression of MUC2 (show MUC2 Proteins) could be important markers for gastric cancer diagnosis.

  6. KLF4 expression was significantly downregulated in gastric cancer. Negative correlation between miR (show MLXIP Proteins)-32 and KLF4 expression and a positive correlation between KLF4 and SNHG5 expression levels were detected.

  7. our results delineate a novel mechanism of cancer stem cell regulation by the DYRK2 (show DYRK2 Proteins)-AR-KLF4 axis. Restoration of the expression and function of DYRK2 (show DYRK2 Proteins) is a potential therapeutic strategy against breast cancer stem cells.

  8. Overexpression of miR-21, accompanied with KLF4, augmented the epithelial-mesenchymal transition via inactivation of Akt and ERK1/2 pathways.

  9. Kruppel-like factor 4 overexpression inhibited transforming growth factor-beta1, extracellular signal-regulated protein kinase, C-jun N-terminal kinase, and nuclear factor-kappaB expression levels in non-small cell lung cancer cells.

  10. Our results suggest that the high Kruppel-like factor 4 expression can be used as a novel biomarker to predict radiation therapy resistance and poor prognosis for locally advanced cervical squamous cell carcinoma.

Xenopus laevis Kruppel-Like Factor 4 (Gut) (KLF4) interaction partners

  1. Klf4 is transcribed both maternally and zygotically and the transcript is ubiquitous in embryos during germ-layer formation

Mouse (Murine) Kruppel-Like Factor 4 (Gut) (KLF4) interaction partners

  1. loss of KLF4 and expression of MUC2 (show MUC2 Proteins) could be important markers for gastric cancer diagnosis.

  2. Mouse embryos deficient in Orai1 (show TMEM132A Proteins), Klf2 (show KLF2 Proteins), or Klf4 showed a significantly reduced lymphatic density and impaired lymphatic development.

  3. During Mycobacterium tuberculosis infection, downregulation of miR (show MLXIP Proteins)-26a facilitates upregulation of KLF4.

  4. Data show that expression of the Oct-4 (show POU5F1 Proteins), Sox2 (show SOX2 Proteins), Klf4, and c-Myc (show MYC Proteins) (OSKM) reprogramming factors induces Cyclin D1 (show CCND1 Proteins) expression, and the increased Cyclin D1 (show CCND1 Proteins) expression during reprogramming promotes continuing embryonic fibroblasts (MEFs) proliferation.

  5. endogenous KLF4 and Krox20 (show EGR2 Proteins) are dispensable for adipogenesis in culture and for brown adipose tissue development in mice. In contrast, the master adipogenic transcription factor peroxisome proliferator-activated receptor gamma (PPARgamma (show PPARG Proteins)) is essential.

  6. Kruppel-like factor 4 was found to be a target gene of miR (show MLXIP Proteins)-10b in the enhancement of spermatogonial stem cell proliferation

  7. The role of Glu446 in Klf4 preference for DNA methylation (show HELLS Proteins)

  8. Induction of the transcription factor Klf4 in differentiated smooth muscle cells is essential for smooth muscle cell reprogramming.

  9. KLF4 expression is negatively correlated to the Notch (show NOTCH1 Proteins) pathway in hepatic stellate cells.

  10. Data show that the reprogramming factors OCT4 (show POU5F1 Proteins), SOX2 (show SOX2 Proteins), KLF4, and MYC (show MYC Proteins) (OSKM) drive cells along two distinct and parallel pathways, one pluripotent and one endodermal.

Pig (Porcine) Kruppel-Like Factor 4 (Gut) (KLF4) interaction partners

  1. miR (show MYLIP Proteins)-92a coregulates KLF4 and KLF2 (show KLF2 Proteins) expression in arterial endothelium and contributes to phenotype heterogeneity associated with regional atherosusceptibility and protection in vivo.

KLF4 Protein Profile

Protein Summary

a transcription factor that works with Sp1 to activate the Laminin gamma1 chain gene

Alternative names and synonyms associated with KLF4

  • Kruppel-like factor 4 (gut) (KLF4)
  • Kruppel-like factor 4a (klf4a)
  • Kruppel-like factor 4 (klf4)
  • Kruppel-like factor 4 (gut) (klf4)
  • Kruppel-like factor 4 (gut) (Klf4)
  • biklf protein
  • biklf-A protein
  • EZF protein
  • Gklf protein
  • KLF4 protein
  • Zie protein

Protein level used designations for KLF4

Krueppel-like factor 4 , Kruppel-like transcription factor 4a , Kruppel-like factor 4 (gut) , Kruppel-like factor 4 , endothelial Kruppel-like zinc finger protein , epithelial zinc finger protein EZF , gut-enriched krueppel-like factor , Kruppel-like transcription factor , blood island enriched kruppel like factor , Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF)

100302636 Ovis aries
100054047 Equus caballus
562155 Danio rerio
711169 Macaca mulatta
100217346 Salmo salar
100379626 Felis catus
9314 Homo sapiens
379518 Xenopus laevis
770254 Gallus gallus
16600 Mus musculus
114505 Rattus norvegicus
520842 Bos taurus
595111 Sus scrofa
100735339 Cavia porcellus
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