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Browse our KLF4 Proteins (KLF4)

Full name:
Kruppel-Like Factor 4 (Gut) Proteins (KLF4)
On are 14 Kruppel-Like Factor 4 (Gut) (KLF4) Proteins from 8 different suppliers available. Additionally we are shipping KLF4 Antibodies (269) and KLF4 Kits (8) and many more products for this protein. A total of 307 KLF4 products are currently listed.
biklf, biklf-A, EZF, Gklf, KLF4, Zie
list all proteins Gene Name GeneID UniProt
KLF4 9314 O43474
KLF4 16600 Q60793
Rat KLF4 KLF4 114505  

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KLF4 Proteins (KLF4) by Origin

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Top referenced KLF4 Proteins

  1. Human KLF4 Protein expressed in Wheat germ - ABIN1308754 : Rivero, Díaz-Guerra, Monsalve, Laborda, García-Ramírez: DLK2 is a transcriptional target of KLF4 in the early stages of adipogenesis. in Journal of molecular biology 2012 (PubMed)
    Show all 2 references for ABIN1308754

  2. Human KLF4 Protein expressed in Escherichia coli (E. coli) - ABIN667940 : Geiman, Ton-That, Johnson, Yang: Transactivation and growth suppression by the gut-enriched Krüppel-like factor (Krüppel-like factor 4) are dependent on acidic amino acid residues and protein-protein interaction. in Nucleic acids research 2000 (PubMed)
    Show all 2 references for ABIN667940

  3. Human KLF4 Protein expressed in HEK-293 Cells - ABIN2724292 : Boxer, Barajas, Tao, Zhang, Khavari: ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes. in Genes & development 2014 (PubMed)
    Show all 2 references for ABIN2724292

More Proteins for KLF4 Interaction Partners

Zebrafish Kruppel-Like Factor 4 (Gut) (KLF4) interaction partners

  1. zebrafih Klf4a is essential for the repression of intestinal cell proliferation

  2. Proper heart valve formation in zebrafish critically depends on protein kinase D2 (show PKD2 Proteins)-histone deacetylase 5 (show HDAC5 Proteins)-Kruppel-like factor signaling.

Human Kruppel-Like Factor 4 (Gut) (KLF4) interaction partners

  1. Our results suggest that the high Kruppel-like factor 4 expression can be used as a novel biomarker to predict radiation therapy resistance and poor prognosis for locally advanced cervical squamous cell carcinoma.

  2. findings support the idea that RYBP (show RYBP Proteins) may represent a target for cancer therapy and suggest that it may be useful as a prognostic biomarker for HCC (show FAM126A Proteins), either alone or in combination with KLF4 and Sp1 (show PSG1 Proteins)

  3. SUMOylation of KLF4 can be a potential therapeutic target in the resolution of inflammation.

  4. we demonstrate that human papillomavirus proteins regulate the expression and activities of a critical cellular transcription factor, KLF4, through post-transcriptional and post-translational mechanisms

  5. KLF4 expression mediated by lentiviral vector or induced by APTO-253 resulted in G1 phase arrest in ovarian cancer cells. Our results demonstrate that for the first time that inducing KLF4 expression with APTO-253 is a novel therapeutic strategy for treating ovarian cancer.

  6. forced expression of KLF4 in plasmablasts enhances the yield of their differentiation into early plasma cell and long lived plasma cells, by inhibiting apoptosis and upregulating previously unknown plasma cell pathways.

  7. BMP4 (show BMP4 Proteins) promotes a phenotype change of an esophageal squamous epithelium via up-regulation of KLF4.

  8. The results suggest that Kruppel-like factor 4 may act as a transcription factor mediating the activation of fibroblast-like synoviocytes in RA by inducing interleukin-6 (show IL6 Proteins) expression in response to tumor necrosis factor-alpha (show TNF Proteins).

  9. Tumor suppressive role of KLF-4 in human endometrial carcinoma tissues.

  10. Osteosarcoma spheres are slowly-proliferating populations, overexpress SOX2 (show SOX2 Proteins), and KLF4 stemness-related genes and have enhanced tumorigenic potential.

Xenopus laevis Kruppel-Like Factor 4 (Gut) (KLF4) interaction partners

  1. Klf4 is transcribed both maternally and zygotically and the transcript is ubiquitous in embryos during germ-layer formation

Mouse (Murine) Kruppel-Like Factor 4 (Gut) (KLF4) interaction partners

  1. During Mycobacterium tuberculosis infection, downregulation of miR (show MLXIP Proteins)-26a facilitates upregulation of KLF4.

  2. Data show that expression of the Oct-4 (show POU5F1 Proteins), Sox2 (show SOX2 Proteins), Klf4, and c-Myc (show MYC Proteins) (OSKM) reprogramming factors induces Cyclin D1 (show CCND1 Proteins) expression, and the increased Cyclin D1 (show CCND1 Proteins) expression during reprogramming promotes continuing embryonic fibroblasts (MEFs) proliferation.

  3. endogenous KLF4 and Krox20 (show EGR2 Proteins) are dispensable for adipogenesis in culture and for brown adipose tissue development in mice. In contrast, the master adipogenic transcription factor peroxisome proliferator-activated receptor gamma (PPARgamma (show PPARG Proteins)) is essential.

  4. Kruppel-like factor 4 was found to be a target gene of miR (show MLXIP Proteins)-10b in the enhancement of spermatogonial stem cell proliferation

  5. The role of Glu446 in Klf4 preference for DNA methylation (show HELLS Proteins)

  6. Induction of the transcription factor Klf4 in differentiated smooth muscle cells is essential for smooth muscle cell reprogramming.

  7. KLF4 expression is negatively correlated to the Notch (show NOTCH1 Proteins) pathway in hepatic stellate cells.

  8. Data show that the reprogramming factors OCT4 (show POU5F1 Proteins), SOX2 (show SOX2 Proteins), KLF4, and MYC (show MYC Proteins) (OSKM) drive cells along two distinct and parallel pathways, one pluripotent and one endodermal.

  9. Study demonstrates that KLF4 plays a significant role in the pathogenesis of colorectal neoplasia.

  10. our study provides valuable information on the molecular interactions between OSKM(Oct4 (show POU5F1 Proteins), Sox2 (show SOX2 Proteins), Klf4, and Myc (show MYC Proteins)) and cofactors and molecular mechanisms for the functional importance of Set1a in ESCs (show NR2E3 Proteins) and early development

Pig (Porcine) Kruppel-Like Factor 4 (Gut) (KLF4) interaction partners

  1. miR (show MYLIP Proteins)-92a coregulates KLF4 and KLF2 (show KLF2 Proteins) expression in arterial endothelium and contributes to phenotype heterogeneity associated with regional atherosusceptibility and protection in vivo.

KLF4 Protein Profile

Protein Summary

a transcription factor that works with Sp1 to activate the Laminin gamma1 chain gene

Alternative names and synonyms associated with KLF4

  • Kruppel-like factor 4 (gut) (KLF4)
  • Kruppel-like factor 4a (klf4a)
  • Kruppel-like factor 4 (klf4)
  • Kruppel-like factor 4 (gut) (klf4)
  • Kruppel-like factor 4 (gut) (Klf4)
  • biklf protein
  • biklf-A protein
  • EZF protein
  • Gklf protein
  • KLF4 protein
  • Zie protein

Protein level used designations for KLF4

Krueppel-like factor 4 , Kruppel-like transcription factor 4a , Kruppel-like factor 4 (gut) , Kruppel-like factor 4 , endothelial Kruppel-like zinc finger protein , epithelial zinc finger protein EZF , gut-enriched krueppel-like factor , Kruppel-like transcription factor , blood island enriched kruppel like factor , Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF)

100302636 Ovis aries
100054047 Equus caballus
562155 Danio rerio
711169 Macaca mulatta
100217346 Salmo salar
100379626 Felis catus
9314 Homo sapiens
379518 Xenopus laevis
770254 Gallus gallus
16600 Mus musculus
114505 Rattus norvegicus
520842 Bos taurus
595111 Sus scrofa
100735339 Cavia porcellus
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