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Browse our anti-PAX6 (PAX6) Antibodies

Full name:
anti-Paired Box 6 Antibodies (PAX6)
On www.antibodies-online.com are 251 Paired Box 6 (PAX6) Antibodies from 25 different suppliers available. Additionally we are shipping PAX6 Proteins (10) and PAX6 Kits (2) and many more products for this protein. A total of 276 PAX6 products are currently listed.
Synonyms:
1500038E17Rik, AEY11, AN, AN2, cb280, D11S812E, Dey, fc20e07, Gsfaey11, MGC52531, MGDA, Pax-6, pax-a, pax6, Pax6.1, pax6a, pax6b, PAXZF-A, paxzfa, pax[zf-a], Sey, WAGR, wu:fc20e07, XLPAX6, xpax6, zfpax-6a, zfpax-6b

Most Popular Reactivities for anti-PAX6 (PAX6) Antibodies

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anti-Rat (Rattus) PAX6 Antibodies:

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anti-Mouse (Murine) PAX6 Antibodies:

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Top referenced anti-PAX6 Antibodies

  1. Human Polyclonal PAX6 Primary Antibody for IF, IHC (p) - ABIN656844 : Gosmain, Marthinet, Cheyssac, Guérardel, Mamin, Katz, Bouzakri, Philippe: Pax6 controls the expression of critical genes involved in pancreatic {alpha} cell differentiation and function. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 references for ABIN656844

  2. Human Polyclonal PAX6 Primary Antibody for EIA, IF - ABIN954011 : Vuzman, Polonsky, Levy: Facilitated DNA search by multidomain transcription factors: cross talk via a flexible linker. in Biophysical journal 2010 (PubMed)
    Show all 2 references for ABIN954011

  3. Cow (Bovine) Polyclonal PAX6 Primary Antibody for WB - ABIN2780375 : Kim, Noh, Ryu, Kim, Lee, Kim, Lee, Kim, Choi: Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2. in The Journal of biological chemistry 2006 (PubMed)

  4. Mouse (Murine) Polyclonal PAX6 Primary Antibody for ELISA, WB - ABIN190794 : von Holst, Egbers, Prochiantz, Faissner: Neural stem/progenitor cells express 20 tenascin C isoforms that are differentially regulated by Pax6. in The Journal of biological chemistry 2007 (PubMed)

  5. Human Polyclonal PAX6 Primary Antibody for IF, IHC (p) - ABIN652261 : Zhang, Yamada, Fan, Bangaru, Lin, Yang: The beta subunit of voltage-gated Ca2+ channels interacts with and regulates the activity of a novel isoform of Pax6. in The Journal of biological chemistry 2010 (PubMed)

  6. Human Polyclonal PAX6 Primary Antibody for EIA, WB - ABIN453253 : Firsova, Markitantova, Smirnova, Panova, Sukhikh, Zinovieva: Temporal and spatial distribution of PAX6 gene expression in the developing human eye. in Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections / translated from Russian 2009 (PubMed)

More Antibodies against PAX6 Interaction Partners

Xenopus laevis Paired Box 6 (PAX6) interaction partners

  1. signaling via Pax6 expression through Shp2-binding sites of XFrs3 is necessary for the eye development in Xenopus laevis

  2. Our results show that the expression of Pax6 and Pax7 (show PAX7 Antibodies) is widely maintained in the adult brain of Xenopus

Human Paired Box 6 (PAX6) interaction partners

  1. PAX6-depleted CECs maintained the epithelial morphology, but became larger. Global analyses using microarray revealed that down-regulated genes were primarily CEC-specific

  2. photoinduced excess electron transfer assay can be used for analysing cooperativity of proteins in transcription complex using cooperative binding of Pax6 to Sox2 (show SOX2 Antibodies) on the regulatory DNA element (DC5 enhancer) as an example.

  3. Data indicate paired box gene 6 (aniridia, keratitis) protein (PAX6) haploinsufficiency as causal for aniridia.

  4. Downregulation of PAX6 is associated with glioma progression.

  5. Overexpression of paired box 6 increased the inhibitory effect of temozolomide on GBM cell proliferation; on the other hand, knockdown of paired box 6 abolished the inhibitory effect of temozolomide on GBM cell proliferation.

  6. the present study identified a heterozygous deletion and a run-on mutation in PAX6 in two families with autosomal dominant aniridia.

  7. Fourteen of these mutations presented in the known aniridia genes; PAX6, FOXC1 (show FOXC1 Antibodies) and PITX2 (show PITX2 Antibodies).

  8. restoration of Notch1 (show NOTCH1 Antibodies) and PAX6 expression partially rescued the inhibition of cell proliferation and metastasis induced by miR (show MLXIP Antibodies)-433 overexpression.

  9. we show that the two PAX6 isoforms differentially and cooperatively regulate the expression of genes specific to the structure and functions of the corneal epithelium, particularly keratin 3 (KRT3) and keratin 12 (KRT12 (show KRT12 Antibodies)). PAX6 isoform-a induced KRT3 expression by targeting its upstream region. KLF4 (show KLF4 Antibodies) enhanced this induction. A combination of PAX6 isoform-b, KLF4 (show KLF4 Antibodies), and OCT4 (show POU5F1 Antibodies) induced KRT12 (show KRT12 Antibodies) expression

  10. We report the first association study of the transcription factor PAX6 with HSCR (show EDNRB Antibodies) and that its low expression levels may result in an aberrant neurogenesis, which is directly related with manifestation of HSCR (show EDNRB Antibodies) phenotype.

Cow (Bovine) Paired Box 6 (PAX6) interaction partners

  1. Some polymorphisms in PAX6 are associated with growth traits at some ages, and may be used as candidates for marker-assisted selection in beef cattle breeding program.

Mouse (Murine) Paired Box 6 (PAX6) interaction partners

  1. These data suggest that Pax6 and Sox2 (show SOX2 Antibodies) have counteracting roles in regulating neurogenesis.

  2. paternal aging has profound effects on the onset of behavioral abnormalities in mice carrying a mutation of Pax6, a gene with neurodevelopmental regulatory functions.

  3. HDAC1 (show HDAC1 Antibodies) binds PAX6 and protein-protein interaction leads to transcriptional repression of PAX6 target genes during mouse retinal development

  4. These results indicate that Pax6 is required for the functional identity of adult beta cells.

  5. we show that simultaneous deletion of Meis1 (show MEIS1 Antibodies) and Meis2 (show MEIS2 Antibodies) in presumptive lens ectoderm results in arrested lens development in the pre-placodal stage, and neither lens placode nor lens is formed. We found that in the presumptive lens ectoderm of Meis1 (show MEIS1 Antibodies)/Meis2 (show MEIS2 Antibodies) deficient embryos Pax6 expression is absent

  6. Results showed that multiple sevoflurane exposure in pregnant mice caused the decrease of Pax6 and Ccnd1 (show CCND1 Antibodies) expression, the inhibition of NSCs proliferation and fetal hippocampus neurogenesis

  7. RIP140 (show NRIP1 Antibodies) protects LSD1 (show KDM1A Antibodies)'s catalytic domain and antagonizes its Jade-2 (show PHF15 Antibodies)-mediated ubiquitination and degradation.

  8. Glucose-stimulated expression of ALX3 (show ALX3 Antibodies) in alpha cells provides a regulatory mechanism for the downregulation of glucagon (show GCG Antibodies) gene expression by interfering with PAX6-mediated transactivation on the glucagon (show GCG Antibodies) G1 promoter element.

  9. c.718C>T transitional mutation of PAX6 has been found to underlie the aniridia, which showed an autosomal dominant inheritance pattern in this northeastern Chinese family

  10. novel mutation in the PAX6 gene has been identified in a Chinese family affected with aniridia

Zebrafish Paired Box 6 (PAX6) interaction partners

  1. Pax6 has an evolutionarily conserved function in establishing the temporospatial expression of Shh (show SHH Antibodies) in the mid-diencephalic organizer in vertebrates.

  2. loss of Pax6b or Hb9 (show MNX1 Antibodies) independently results in the loss of insulin (show INS Antibodies) expression, the data reveal a novel cross-talk between the two essential regulators of early beta-cell differentiation.

  3. The results suggest that decreased Pax6 expression is permissive for axon regeneration and extensive searching, while higher levels of Pax6 are associated with restoration of topography.

  4. This study supports the hypothesis that the Pax6 transcription factor is also a signaling molecule with direct non-cell autonomous activity.

  5. following a postulated whole-genome duplication event in an ancestral teleost, duplicates pax6a and pax6b encode transcription factors required for eye, brain, olfactory system, and pancreas development

  6. Pax6 interacts with itself via both the paired domain and the homeodomain. Pax6 interaction with itself superactivates Pax6 mediated transactivation.

PAX6 Antigen Profile

Antigen Summary

This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with PAX6

  • paired box 6 (PAX6) antibody
  • paired box 6 (pax6) antibody
  • paired box 6 (Pax6) antibody
  • paired box 6 (pax6-a) antibody
  • paired box 6 (pax6-b) antibody
  • paired box gene 6 (Pax6) antibody
  • paired box gene 6a (pax6a) antibody
  • 1500038E17Rik antibody
  • AEY11 antibody
  • AN antibody
  • AN2 antibody
  • cb280 antibody
  • D11S812E antibody
  • Dey antibody
  • fc20e07 antibody
  • Gsfaey11 antibody
  • MGC52531 antibody
  • MGDA antibody
  • Pax-6 antibody
  • pax-a antibody
  • pax6 antibody
  • Pax6.1 antibody
  • pax6a antibody
  • pax6b antibody
  • PAXZF-A antibody
  • paxzfa antibody
  • pax[zf-a] antibody
  • Sey antibody
  • WAGR antibody
  • wu:fc20e07 antibody
  • XLPAX6 antibody
  • xpax6 antibody
  • zfpax-6a antibody
  • zfpax-6b antibody

Protein level used designations for anti-Paired Box 6 (PAX6) Antibodies

paired box protein Pax-6 , paired box 6 , paired box gene 6 , oculorhombin , paired box homeotic gene 6 , paired box gene 6 a , aniridia type II protein , paired box homeotic gene-6 , paired box gene 6 (aniridia, keratitis) , paired box protein PAX6 , paired box gene 6 b , paired domain transcription factor variant B , paired-type homeodomain Pax-6 protein , Dickie's small eye , small eye , etID309716.25 , paired box protein Pax[Zf-a] , pax-6

GENE ID SPECIES
100146390 Equus caballus
695746 Macaca mulatta
100303503 Saccoglossus kowalevskii
100552301 Anolis carolinensis
100590220 Nomascus leucogenys
554264 Ovis aries
25509 Rattus norvegicus
379100 Xenopus laevis
395943 Gallus gallus
5080 Homo sapiens
483441 Canis lupus familiaris
286857 Bos taurus
100009018 Oryctolagus cuniculus
100337586 Xenopus laevis
18508 Mus musculus
30567 Danio rerio
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