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PAX5 Antibodies

(Paired Box 5 (PAX5))
This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9\;14)(p13\;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
anti-Paired Box 5 (PAX5) (AA 192-301) antibody anti-Paired Box 5 (PAX5) (AA 192-301) antibody anti-Paired Box 5 (PAX5) (AA 192-301) antibody (ABIN562112)

PAX5 Reactivity: Human IHC (p), RNAi, ELISA, WB Host: Mouse Monoclonal 8F9 unconjugated

anti-Paired Box 5 (PAX5) (Internal Region) antibody anti-Paired Box 5 (PAX5) (Internal Region) antibody anti-Paired Box 5 (PAX5) (Internal Region) antibody (ABIN3187828)

PAX5 Reactivity: Human, Mouse ELISA, IHC (p), WB Host: Rabbit Polyclonal unconjugated

anti-Paired Box 5 (PAX5) (AA 235-382) antibody anti-Paired Box 5 (PAX5) (AA 235-382) antibody anti-Paired Box 5 (PAX5) (AA 235-382) antibody (ABIN1098104)

PAX5 Reactivity: Human IHC, ELISA, WB Host: Mouse Monoclonal 7D3 unconjugated

PAX5 Antibodies by Grade

Find PAX5 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PAX5 Antibodies by Reactivity

Find PAX5 Antibodies for a variety of species such as anti-Human PAX5, anti-Mouse PAX5, anti-Rat PAX5. The species listed below are among those available. Click on a link to go to the corresponding products.

PAX5 Antibodies by Application

Find PAX5 Antibodies validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PAX5 Antibodies by Host

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PAX5 Antibodies by Binding Specificity

Find PAX5 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PAX5 Antibodies by Clonality

Find available monoclonal or polyclonal PAX5 Antibodies. Click on a link to go to the corresponding products.

PAX5 Antibodies by Clone

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PAX5 Antibodies by Conjugate

Find PAX5 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PAX5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (5)
Cat. No. ABIN6940256
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application FACS, IHC, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3032126
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (4)
Cat. No. ABIN5692907
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (3)
Cat. No. ABIN184804
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application IHC, WB
Validations
  • (3)
Cat. No. ABIN2775953
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN655650
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application EIA, WB
Validations
  • (3)
Cat. No. ABIN954009
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application Coat, ELISA, WB
Validations
  • (2)
Cat. No. ABIN6940254
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, ICC, IF, WB
Validations
  • (2)
Cat. No. ABIN6264049
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN2426335
Quantity 200 μL
Datasheet Datasheet

Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN6735893
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN3180796
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6972489
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application Coat, ELISA
Validations
  • (1)
Cat. No. ABIN6940255
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN5027430
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PAX5 Antibodies

Zhang, Tong, Tan, Peng, He, Wang: "Hemophagocytic lymphohistiocytosis presenting with annular erythema multiforme-like eruptions in a patient with angioimmunoblastic T cell lymphoma: A case report." in: Experimental and therapeutic medicine, Vol. 16, Issue 3, pp. 2060-2065, (2018) (PubMed).

OBrien, Morin, Ouellette, Robichaud: "The Pax-5 gene: a pluripotent regulator of B-cell differentiation and cancer disease." in: Cancer research, Vol. 71, Issue 24, pp. 7345-50, (2011) (PubMed).

Mortensen, Soilleux, Djordjevic, Tripp, Lutteropp, Sadighi-Akha, Stranks, Glanville, Knight, Jacobsen, Kranc, Simon: "The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance." in: The Journal of experimental medicine, Vol. 208, Issue 3, pp. 455-67, (2011) (PubMed).

Coyaud, Struski, Prade, Familiades, Eichner, Quelen, Bousquet, Mugneret, Talmant, Pages, Lefebvre, Penther, Lippert, Nadal, Taviaux, Poppe, Luquet, Baranger, Eclache, Radford, Barin, Mozziconacci et al.: "Wide diversity of PAX5 alterations in B-ALL: a Groupe Francophone de Cytogenetique Hematologique study. ..." in: Blood, Vol. 115, Issue 15, pp. 3089-97, (2010) (PubMed).

Nasr, Rosenthal, Syrbu: "Expression profiling of transcription factors in B- or T-acute lymphoblastic leukemia/lymphoma and burkitt lymphoma: usefulness of PAX5 immunostaining as pan-Pre-B-cell marker." in: American journal of clinical pathology, Vol. 133, Issue 1, pp. 41-8, (2009) (PubMed).

Arseneau, Laflamme, Lewis, Maïcas, Ouellette: "Multiple isoforms of PAX5 are expressed in both lymphomas and normal B-cells." in: British journal of haematology, Vol. 147, Issue 3, pp. 328-38, (2009) (PubMed).

Klein, Tu, Stolovitzky, Keller, Haddad, Miljkovic, Cattoretti, Califano, Dalla-Favera: "Transcriptional analysis of the B cell germinal center reaction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2639-44, (2003) (PubMed).

Hertel, Zhou, Hamilton-Dutoit, Junker: "Loss of B cell identity correlates with loss of B cell-specific transcription factors in Hodgkin/Reed-Sternberg cells of classical Hodgkin lymphoma." in: Oncogene, Vol. 21, Issue 32, pp. 4908-20, (2002) (PubMed).

Foss, Reusch, Demel, Lenz, Anagnostopoulos, Hummel, Stein: "Frequent expression of the B-cell-specific activator protein in Reed-Sternberg cells of classical Hodgkin's disease provides further evidence for its B-cell origin." in: Blood, Vol. 94, Issue 9, pp. 3108-13, (1999) (PubMed).

Zwollo, Arrieta, Ede, Molinder, Desiderio, Pollock: "The Pax-5 gene is alternatively spliced during B-cell development." in: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10160-8, (1997) (PubMed).

Aliases for PAX5 Antibodies

paired box 5 (PAX5) Antibodies
paired box 5 L homeolog (pax5.L) Antibodies
paired box 5 (Pax5) Antibodies
paired box 5 (pax5) Antibodies
BSAP Antibodies
EBB-1 Antibodies
KLP Antibodies
noi Antibodies
Pax-5 Antibodies
pax2.1 Antibodies
pax2a Antibodies
PAX5 Antibodies
pax5-a Antibodies
paxzf-b Antibodies
Pax[Zf-b] Antibodies
RGD1565236 Antibodies
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