PAX6 antibody (AA 352-380)

Catalog No. ABIN3032127

Product Details anti-PAX6 Antibody

Target: PAX6 (Paired Box 6 (PAX6))

Binding Specificity: AA 352-380

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 352-380 from the human protein was used as the immunogen for this PAX-6 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PAX-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PAX-6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Alternative Name: PAX-6 (PAX6 Products)

Background: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). [UniProt]

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis