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Browse our anti-PDPK1 (PDPK1) Antibodies

Full name:
anti-3-phosphoinositide Dependent Protein Kinase-1 Antibodies (PDPK1)
On www.antibodies-online.com are 293 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) Antibodies from 27 different suppliers available. Additionally we are shipping PDPK1 Kits (14) and PDPK1 Proteins (12) and many more products for this protein. A total of 342 PDPK1 products are currently listed.
Synonyms:
1210, BG02759, CD79B, CG1201, CG1210, Dmel\\CG1210, dPDK-1, dPDK1, dSTPK61, LOC100304995, MGC82080, PDK, PDK-1, Pdk1, PDK1/Pk61C, pdpk1, PDPK2, pk61c, Pk61C/PDK1, PRO0461, zgc:153787
list all antibodies Gene Name GeneID UniProt
PDPK1 18607 Q9Z2A0
PDPK1 5170 O15530
PDPK1 81745 O55173

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Most Popular Reactivities for anti-PDPK1 (PDPK1) Antibodies

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anti-Mouse (Murine) PDPK1 Antibodies:

anti-Human PDPK1 Antibodies:

anti-Rat (Rattus) PDPK1 Antibodies:

All available anti-PDPK1 Antibodies

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Top referenced anti-PDPK1 Antibodies

  1. Human Polyclonal PDPK1 Primary Antibody for WB - ABIN116939 : Noppert, Mayer: In search for the troponin of the kidney. in Current medicinal chemistry 2009 (PubMed)
    Show all 6 references for ABIN116939

  2. Human Polyclonal PDPK1 Primary Antibody for IF, IHC (p) - ABIN197100 : Scheid, Parsons, Woodgett: Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation. in Molecular and cellular biology 2005 (PubMed)
    Show all 5 references for ABIN197100

  3. Dog (Canine) Monoclonal PDPK1 Primary Antibody for IF, WB - ABIN968351 : Fujita, Sato, Ishida, Tsuruo: Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN968351

  4. Human Polyclonal PDPK1 Primary Antibody for EIA - ABIN358390 : Nilsen, Slagsvold, Skjerpen, Brech, Stenmark, Olsnes: Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358390

  5. Human Polyclonal PDPK1 Primary Antibody for IF, IHC (p) - ABIN196616 : Chen, Nystrom, Dong, Li, Song, Liu, Quon: Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism. in Biochemistry 2001 (PubMed)
    Show all 4 references for ABIN196616

  6. Human Monoclonal PDPK1 Primary Antibody for WB - ABIN967612 : Komander, Kular, Deak, Alessi, van Aalten: Role of T-loop phosphorylation in PDK1 activation, stability, and substrate binding. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for ABIN967612

  7. Human Polyclonal PDPK1 Primary Antibody for IHC, ELISA - ABIN1532025 : Stephens, Anderson, Stokoe, Erdjument-Bromage, Painter, Holmes, Gaffney, Reese, McCormick, Tempst, Coadwell, Hawkins: Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. in Science (New York, N.Y.) 1998 (PubMed)

  8. Human Polyclonal PDPK1 Primary Antibody for WB - ABIN2779320 : Lin, Hsieh, Song, Lin: Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer. in British journal of cancer 2005 (PubMed)

More Antibodies against PDPK1 Interaction Partners

Fruit Fly (Drosophila melanogaster) 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) interaction partners

  1. PDK1 is also a presynaptic protein, though it is distributed more broadly.

  2. dS6K activity is dependent on the Drosophila homologue of the phosphoinositide-dependent protein kinase (show CDK7 Antibodies) 1, dPDK1

Mouse (Murine) 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) interaction partners

  1. PDPK1 is required for exercise-induced cardiac hypertrophy but does not contribute to exercise-induced increases in mitochondrial function.

  2. The PDK1 knock-in mice displayed a reduced brain size due to a reduction in neuronal cell size rather than cell number.

  3. PDK1 is an important regulator in arterial thrombosis formation.

  4. PDK1 is essential for BCR (show BCR Antibodies)-induced signal transduction to Foxo (show FOXO3 Antibodies) and NF-kappaB (show NFKB1 Antibodies) and is indispensable for both resting and activated B cell survival.

  5. Results suggest that heat shock protein 90 (show HSP90 Antibodies) inhibitor radicicol inhibited 3T3-L1 preadipocyte differentiation through affecting the PDK1/Akt (show AKT1 Antibodies) pathway.

  6. Inhibition of PDK1 promotes localization of TACE (show ADAM17 Antibodies) to the plasma membrane, restores TACE (show ADAM17 Antibodies)-dependent alpha-secretase activity and cleavage of APP (show APP Antibodies), PrP(C (show PRNP Antibodies)) and TNFR1 (show TNFRSF1A Antibodies), and attenuates PrP(Sc)- and Abeta (show APP Antibodies)-induced neurotoxicity.

  7. Data show that insulin (show INS Antibodies) stimulates GLUT4 (show SLC2A4 Antibodies) translocation to the cell surface and iglucose uptake in an Akt1 (show AKT1 Antibodies)/2-dependent manner; PI3K phosphorylates Thr308 and Ser473 for Akt1 (show AKT1 Antibodies) and Ser474 alone for Akt2 (show AKT2 Antibodies); and PDK1 phosphorylates Thr308 for Akt1 (show AKT1 Antibodies) and Akt2 (show AKT2 Antibodies).

  8. Direct genetic evidence for the importance of PDK1, in part through FOXO3a (show FOXO3 Antibodies)-dependent pathway, in melanoma development and progression.

  9. These results indicate that PDK1 participates in the dysregulation of electrophysiological basis by regulating the PDK1-Foxo1 (show FOXO1 Antibodies) pathway

  10. T34 phosphorylation by PDK1 promotes the membrane dissociation of activated Akt (show AKT1 Antibodies) for its downstream action through attenuating membrane binding affinity.

Human 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) interaction partners

  1. Decreased PDK1 (show PDK1 Antibodies) level is closely associated with reduced Akt (show AKT1 Antibodies)/cyclin D1 (show CCND1 Antibodies) activity.

  2. MiR (show MLXIP Antibodies)-138 regulation of PI3K (show PIK3CA Antibodies) signaling in ASMCs by altering the expression of PDK1 (show PDK1 Antibodies).

  3. Dephosphorylation of PDK-1 (show PDK1 Antibodies) and the resulting changes to Akt (show AKT1 Antibodies) phosphorylation is one of the mechanisms by which infection with Helicobacter pylori alter the balance between apoptosis and cell proliferation.

  4. Data suggest that claudin-18 (show CLDN18 Antibodies) suppresses the abnormal proliferation and motility of lung epithelial cells mediated by inhibition of phosphorylation of phosphoinositide-dependent protein kinase (show CDK7 Antibodies)-1 and proto-oncogene (show RAB1A Antibodies) protein c (show PROC Antibodies)-akt (Akt (show AKT1 Antibodies)).

  5. DK1 (show DOLK Antibodies) inhibits the formation of the TAK1 (show MAP3K7 Antibodies)-TAB2 (show TAB2 Antibodies)-TRAF6 (show TRAF6 Antibodies) complex and leads to the inhibition of TRAF6 (show TRAF6 Antibodies) ubiquitination.

  6. Data show that NSC156529 inhibits the interaction of endogenous serine/threonine kinase (show TLK2 Antibodies) AKT (AKT1 (show AKT1 Antibodies)) and 3-phosphoinositide dependent protein kinase-1 (PDPK1) proteins.

  7. PDK1 (show PDK1 Antibodies) functions as a tumor promoter in human gallbladder cancer by upregulating JunB (show JUNB Antibodies), promoting epithelial mesenchymal transformation, and cell migration.

  8. PGE2 increases normal bronchial epithelial cell proliferation through increased PDK1 (show PDK1 Antibodies) gene expression that is dependent on EP4 (show PTGER4 Antibodies) and induction of c-Jun (show JUN Antibodies).

  9. data show that PDK1 (show PDK1 Antibodies) played a pivotal role in the growth of angiosarcoma cells.

  10. findings show that PDK1 (show PDK1 Antibodies)-PLK1 (show PLK1 Antibodies)-MYC (show MYC Antibodies) signaling is critical for cancer cell growth and survival; PDK1 (show PDK1 Antibodies)-PLK1 (show PLK1 Antibodies)-MYC (show MYC Antibodies) signaling induces an embryonic stem cell-like gene signature associated with aggressive tumor behaviors and is a robust signaling axis driving cancer stem cell self-renewal

Caenorhabditis elegans (C. elegans) 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) interaction partners

  1. at least three C. elegans MTMs play essential roles in coelomocyte endocytosis, a process that also requires VPS34 (show PIK3C3 Antibodies) (PI3K)

PDPK1 Antigen Profile

Antigen Summary

Serine/threonine kinase required for embryonic development. Inhibits apoptosis. Acts in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and activating Akt1 and S6k. May be involved in axonal pathfinding and synaptogenesis, and in spermatogenesis.

Alternative names and synonyms associated with PDPK1

  • Phosphoinositide-dependent kinase 1 (Pdk1) antibody
  • 3-phosphoinositide dependent protein kinase-1 (pdpk1) antibody
  • 3-phosphoinositide dependent protein kinase-1a (pdpk1a) antibody
  • CD79b molecule, immunoglobulin-associated beta (CD79B) antibody
  • CD79b molecule, immunoglobulin-associated beta (CD79b) antibody
  • CD79b (LOC100304995) antibody
  • 3-phosphoinositide-dependent protein kinase 1 (pdpk1) antibody
  • 3-phosphoinositide dependent protein kinase 1 (Pdpk1) antibody
  • 3-phosphoinositide dependent protein kinase-1 (PDPK1) antibody
  • 3-phosphoinositide dependent protein kinase-1 (Pdpk1) antibody
  • Protein PDK-1 (pdk-1) antibody
  • 1210 antibody
  • BG02759 antibody
  • CD79B antibody
  • CG1201 antibody
  • CG1210 antibody
  • Dmel\\CG1210 antibody
  • dPDK-1 antibody
  • dPDK1 antibody
  • dSTPK61 antibody
  • LOC100304995 antibody
  • MGC82080 antibody
  • PDK antibody
  • PDK-1 antibody
  • Pdk1 antibody
  • PDK1/Pk61C antibody
  • pdpk1 antibody
  • PDPK2 antibody
  • pk61c antibody
  • Pk61C/PDK1 antibody
  • PRO0461 antibody
  • zgc:153787 antibody

Protein level used designations for PDPK1

CG1210-PA , CG1210-PB , CG1210-PC , CG1210-PD , CG1210-PE , CG1210-PF , CG1210-PG , CG1210-PH , CG1210-PI , CG1210-PJ , Pdk1-PA , Pdk1-PB , Pdk1-PC , Pdk1-PD , Pdk1-PE , Pdk1-PF , Pdk1-PG , Pdk1-PH , Pdk1-PI , Pdk1-PJ , phosphoinositide dependent kinase 1 , phosphoinositide-dependent kinase 1 , protein kinase 61C , serine/threonine protein kinase , 3-phosphoinositide dependent protein kinase-1 , 3-phosphoinositide-dependent protein kinase 1 , B-cell antigen receptor complex-associated protein beta chain , CD79b molecule, immunoglobulin-associated beta , CD79b , Pkb kinase , mPDK1 , PkB kinase like gene 1 , pkB kinase , protein kinase B kinase

GENE ID SPECIES
38017 Drosophila melanogaster
444529 Xenopus laevis
779524 Xenopus (Silurana) tropicalis
768202 Danio rerio
419940 Gallus gallus
454773 Pan troglodytes
100026330 Monodelphis domestica
100304995 Ictalurus punctatus
100471131 Ailuropoda melanoleuca
100380750 Salmo salar
18607 Mus musculus
5170 Homo sapiens
81745 Rattus norvegicus
100192445 Sus scrofa
416588 Gallus gallus
479875 Canis lupus familiaris
100138102 Bos taurus
180475 Caenorhabditis elegans
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