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Browse our anti-PDPK1 (PDPK1) Antibodies

Full name:
anti-3-phosphoinositide Dependent Protein Kinase-1 Antibodies (PDPK1)
On www.antibodies-online.com are 250 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) Antibodies from 26 different suppliers available. Additionally we are shipping PDPK1 Kits (14) and PDPK1 Proteins (12) and many more products for this protein. A total of 299 PDPK1 products are currently listed.
Synonyms:
1210, BG02759, CD79B, CG1201, CG1210, Dmel\\CG1210, dPDK-1, dPDK1, dSTPK61, LOC100304995, MGC82080, PDK, PDK-1, Pdk1, PDK1/Pk61C, pdpk1, PDPK2, pk61c, Pk61C/PDK1, PRO0461, zgc:153787
list all antibodies Gene Name GeneID UniProt
PDPK1 18607 Q9Z2A0
PDPK1 5170 O15530
PDPK1 81745 O55173

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Top referenced anti-PDPK1 Antibodies

  1. Human Polyclonal PDPK1 Primary Antibody for WB - ABIN116939 : Noppert, Mayer: In search for the troponin of the kidney. in Current medicinal chemistry 2009 (PubMed)
    Show all 6 references for ABIN116939

  2. Human Polyclonal PDPK1 Primary Antibody for IF, IHC (p) - ABIN197100 : Scheid, Parsons, Woodgett: Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation. in Molecular and cellular biology 2005 (PubMed)
    Show all 5 references for ABIN197100

  3. Dog (Canine) Monoclonal PDPK1 Primary Antibody for IF, WB - ABIN968351 : Fujita, Sato, Ishida, Tsuruo: Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN968351

  4. Human Polyclonal PDPK1 Primary Antibody for EIA - ABIN358390 : Nilsen, Slagsvold, Skjerpen, Brech, Stenmark, Olsnes: Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358390

  5. Human Polyclonal PDPK1 Primary Antibody for IF, IHC (p) - ABIN196616 : Chen, Nystrom, Dong, Li, Song, Liu, Quon: Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism. in Biochemistry 2001 (PubMed)
    Show all 4 references for ABIN196616

  6. Human Monoclonal PDPK1 Primary Antibody for WB - ABIN967612 : Komander, Kular, Deak, Alessi, van Aalten: Role of T-loop phosphorylation in PDK1 activation, stability, and substrate binding. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for ABIN967612

  7. Human Polyclonal PDPK1 Primary Antibody for IHC, ELISA - ABIN1532025 : Stephens, Anderson, Stokoe, Erdjument-Bromage, Painter, Holmes, Gaffney, Reese, McCormick, Tempst, Coadwell, Hawkins: Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. in Science (New York, N.Y.) 1998 (PubMed)

  8. Human Polyclonal PDPK1 Primary Antibody for WB - ABIN2779320 : Lin, Hsieh, Song, Lin: Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer. in British journal of cancer 2005 (PubMed)

More Antibodies against PDPK1 Interaction Partners

Fruit Fly (Drosophila melanogaster) 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) interaction partners

  1. PDK1 is also a presynaptic protein, though it is distributed more broadly.

  2. dS6K activity is dependent on the Drosophila homologue of the phosphoinositide-dependent protein kinase (show CDK7 Antibodies) 1, dPDK1

Mouse (Murine) 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) interaction partners

  1. Data show that the phosphoinositide-dependent kinase 1 (PDK1)-p90 (show GPAM Antibodies) kDa ribosomal S6 kinases (Rsks) Rsk1 (show RPS6KA1 Antibodies)/2 pathway is critical for establishment and maintenance of a normal Langerhans cells (LC) network.

  2. Data illustrate a critical role for PDK1 in transducing inhibitory signals on eosinophil effector function. Stimulation of EP4 (show PTGER4 Antibodies) receptors caused PDK1 phosphorylation at Ser396 and induced PI3K-dependent nuclear translocation of PDK1.

  3. Using a PDK1 conditional deletion MLL (show MLL Antibodies)-AF9 (show MLLT3 Antibodies) murine AML (show RUNX1 Antibodies) model, we revealed that the deletion of PDK1 prolonged the survival of AML (show RUNX1 Antibodies) mice by inducing LSC (show ARHGEF1 Antibodies) apoptosis

  4. The B cell receptor and a subset of cytokine receptors require PDK1 for B cell generation in the bone marrow as well as for mature B cell survival and activation.

  5. These results demonstrated that PDK1 and mTORC2 (show CRTC2 Antibodies) synergistically promote postnatal heart growth and maintain heart function in postnatal mice.

  6. these results indicate that activation of PDK-1 (show PDK1 Antibodies) maintains mouse embryonic stem cell self-renewal in a protein kinase B (show AKT1 Antibodies) dependent manner in the absence of leukemia inhibitory factor (show LIF Antibodies).

  7. PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development.

  8. cytoplasmic localization of PDK1 correlated only with early-stage, low-risk tumors, whereas nuclear PDK1 localization correlated with high-risk tumors

  9. PDK1 regulation of mTOR (show FRAP1 Antibodies) and hypoxia-inducible factor 1 (show HIF1A Antibodies) integrate metabolism and migration of CD8 (show CD8A Antibodies)+ T cells.

  10. Pdk1 deletion in bone marrow-derived macrophages abolished insulin (show INS Antibodies) and interleukin-4 (show IL4 Antibodies) induction of genes involved in alternative macrophage activation.

Human 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) interaction partners

  1. PDK1 (show PDK1 Antibodies) functions as a tumor promoter in human gallbladder cancer by upregulating JunB (show JUNB Antibodies), promoting epithelial mesenchymal transformation, and cell migration.

  2. PGE2 increases normal bronchial epithelial cell proliferation through increased PDK1 (show PDK1 Antibodies) gene expression that is dependent on EP4 (show PTGER4 Antibodies) and induction of c-Jun (show JUN Antibodies).

  3. data show that PDK1 (show PDK1 Antibodies) played a pivotal role in the growth of angiosarcoma cells.

  4. findings show that PDK1 (show PDK1 Antibodies)-PLK1 (show PLK1 Antibodies)-MYC (show MYC Antibodies) signaling is critical for cancer cell growth and survival; PDK1 (show PDK1 Antibodies)-PLK1 (show PLK1 Antibodies)-MYC (show MYC Antibodies) signaling induces an embryonic stem cell-like gene signature associated with aggressive tumor behaviors and is a robust signaling axis driving cancer stem cell self-renewal

  5. Data propose that PDK1 functions as a cellular sensor that balances basal PIP3 generation at levels sufficient for survival but below a threshold being harmful to the cell.

  6. The crystal structural analysis of PDK1 (show PDK1 Antibodies) located the PIF (show PIF1 Antibodies)-pocket as the catalytic domain and for substrate recognition.

  7. these data show that overexpression of PDK1 (show PDK1 Antibodies) is common in acute myelomonocytic leukemia and is associated with poorer treatment outcome, probably arising from the cytoprotective function of PDK1 (show PDK1 Antibodies).

  8. phosphorylating the T-loop Akt (show AKT1 Antibodies) residue Thr (show TRH Antibodies)(308) by PDK1 (show PDK1 Antibodies) requires Raptor (show RPTOR Antibodies) of the mTORC1 complex as a platform or scaffold protein (show HOMER1 Antibodies).

  9. Combined inhibition of PDK1 (show PDK1 Antibodies) and CHK1 (show CHEK1 Antibodies) represents a potentially effective therapeutic approach to reduce the growth of human glioblastoma.

  10. our results demonstrate that ciglitazone inhibits PDK1 (show PDK1 Antibodies) expression through AMPKalpha (show GRK4 Antibodies)-mediated induction of Egr-1 (show EGR1 Antibodies) and Egr-1 (show EGR1 Antibodies) binding to the specific DNA site in the PDK1 (show PDK1 Antibodies) gene promoter, which is independent of PPARgamma (show PPARG Antibodies)

Caenorhabditis elegans (C. elegans) 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) interaction partners

  1. at least three C. elegans MTMs play essential roles in coelomocyte endocytosis, a process that also requires VPS34 (show PIK3C3 Antibodies) (PI3K)

PDPK1 Antigen Profile

Antigen Summary

Serine/threonine kinase required for embryonic development. Inhibits apoptosis. Acts in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and activating Akt1 and S6k. May be involved in axonal pathfinding and synaptogenesis, and in spermatogenesis.

Alternative names and synonyms associated with PDPK1

  • Phosphoinositide-dependent kinase 1 (Pdk1) antibody
  • 3-phosphoinositide dependent protein kinase-1 (pdpk1) antibody
  • 3-phosphoinositide dependent protein kinase-1a (pdpk1a) antibody
  • CD79b molecule, immunoglobulin-associated beta (CD79B) antibody
  • CD79b molecule, immunoglobulin-associated beta (CD79b) antibody
  • CD79b (LOC100304995) antibody
  • 3-phosphoinositide-dependent protein kinase 1 (pdpk1) antibody
  • 3-phosphoinositide dependent protein kinase 1 (Pdpk1) antibody
  • 3-phosphoinositide dependent protein kinase-1 (PDPK1) antibody
  • 3-phosphoinositide dependent protein kinase-1 (Pdpk1) antibody
  • Protein PDK-1 (pdk-1) antibody
  • 1210 antibody
  • BG02759 antibody
  • CD79B antibody
  • CG1201 antibody
  • CG1210 antibody
  • Dmel\\CG1210 antibody
  • dPDK-1 antibody
  • dPDK1 antibody
  • dSTPK61 antibody
  • LOC100304995 antibody
  • MGC82080 antibody
  • PDK antibody
  • PDK-1 antibody
  • Pdk1 antibody
  • PDK1/Pk61C antibody
  • pdpk1 antibody
  • PDPK2 antibody
  • pk61c antibody
  • Pk61C/PDK1 antibody
  • PRO0461 antibody
  • zgc:153787 antibody

Protein level used designations for PDPK1

CG1210-PA , CG1210-PB , CG1210-PC , CG1210-PD , CG1210-PE , CG1210-PF , CG1210-PG , CG1210-PH , CG1210-PI , CG1210-PJ , Pdk1-PA , Pdk1-PB , Pdk1-PC , Pdk1-PD , Pdk1-PE , Pdk1-PF , Pdk1-PG , Pdk1-PH , Pdk1-PI , Pdk1-PJ , phosphoinositide dependent kinase 1 , phosphoinositide-dependent kinase 1 , protein kinase 61C , serine/threonine protein kinase , 3-phosphoinositide dependent protein kinase-1 , 3-phosphoinositide-dependent protein kinase 1 , B-cell antigen receptor complex-associated protein beta chain , CD79b molecule, immunoglobulin-associated beta , CD79b , Pkb kinase , mPDK1 , PkB kinase like gene 1 , pkB kinase , protein kinase B kinase

GENE ID SPECIES
38017 Drosophila melanogaster
444529 Xenopus laevis
779524 Xenopus (Silurana) tropicalis
768202 Danio rerio
419940 Gallus gallus
454773 Pan troglodytes
100026330 Monodelphis domestica
100304995 Ictalurus punctatus
100471131 Ailuropoda melanoleuca
100380750 Salmo salar
18607 Mus musculus
5170 Homo sapiens
81745 Rattus norvegicus
100192445 Sus scrofa
416588 Gallus gallus
479875 Canis lupus familiaris
100138102 Bos taurus
180475 Caenorhabditis elegans
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