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PDHX Antibodies (Pyruvate Dehydrogenase Complex, Component X, PDHX)

Short Description: The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit\; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood. This protein is also a minor antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009].

Available PDHX Antibodies:

42 results:

anti-PDHX antibody (Pyruvate Dehydrogenase Complex, Component X) (AA 1-501) Primary Antibody

PDHX Reactivity: Human IF, WB Host: Mouse Polyclonal unconjugated
Catalog No. ABIN521742
$600.00
Plus shipping costs $45.00
50 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-PDHX antibody (Pyruvate Dehydrogenase Complex, Component X) (AA 1-501) Primary Antibody

PDHX Reactivity: Human IP, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN948658
$585.71
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-PDHX antibody (Pyruvate Dehydrogenase Complex, Component X) (C-Term) Primary Antibody

PDHX Reactivity: Human, Mouse EIA, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN357414
$629.20
Plus shipping costs $45.00
0.4 mL
local_shipping Shipping to: United States
Available

anti-PDHX antibody (Pyruvate Dehydrogenase Complex, Component X) (C-Term) Primary Antibody

Verified PDHX Reactivity: Human ELISA, WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN185389
$451.79
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 6 to 7 Business Days

anti-PDHX antibody (Pyruvate Dehydrogenase Complex, Component X) (full length) Primary Antibody

PDHX Reactivity: Human IF/ICC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6004320
$382.36
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 18 Business Days

anti-PDHX antibody (Pyruvate Dehydrogenase Complex, Component X) (AA 1-109) Primary Antibody

PDHX Reactivity: Human ELISA, WB Host: Mouse Polyclonal unconjugated
Catalog No. ABIN563534
$465.71
Plus shipping costs $45.00
50 μL
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-PDHX antibody (Pyruvate Dehydrogenase Complex, Component X) Primary Antibody

PDHX Reactivity: Human IC, IF, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2966587
$487.50
Plus shipping costs $45.00
200 μL
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-PDHX antibody (Pyruvate Dehydrogenase Complex, Component X) (C-Term) Primary Antibody

PDHX Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856340
$509.08
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 3 to 4 Business Days

anti-PDHX antibody (Pyruvate Dehydrogenase Complex, Component X) Primary Antibody

PDHX Reactivity: Human Host: Mouse Monoclonal AT1E11 unconjugated
Catalog No. ABIN5775964
$611.54
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 13 to 16 Business Days

anti-PDHX antibody (Pyruvate Dehydrogenase Complex, Component X) Primary Antibody

PDHX Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7011114
$204.60
Plus shipping costs $45.00
60 μL
local_shipping Shipping to: United States
Delivery in 8 to 11 Business Days
  • Type Primary
    • Primary
  • Application
    • Western Blotting (WB)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunofluorescence (IF)
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Enzyme Immunoassay (EIA)
    • Flow Cytometry (FACS)
    • Immunochromatography (IC)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Images available
  • Preservative free only
  • Host
    • Rabbit
    • Mouse
    • Goat
    • Sheep
  • Clonality
    • Polyclonal
    • Monoclonal
  • Clone
    • AT1E11
  • Binding Specificity
    • AA 231-330
    • C-Term
    • AA 1-501
    • AA 1-109
    • AA 1-300
    • AA 220-468
    • AA 222-471
    • AA 387-501
    • AA 429-459
    • Middle Region
    • Thr11
    • full length
  • Conjugate
    • Un-conjugated
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • Biotin
    • Alexa Fluor 350
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • FITC
    • HRP
  • Isotype
    • IgG
    • Ig Fraction
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
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