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PDHX Antibodies

(Pyruvate Dehydrogenase Complex, Component X (PDHX))
The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit\; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood. This protein is also a minor antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009].
PDHX antibody  (AA 220-468) PDHX antibody  (AA 220-468) PDHX antibody (AA 220-468) (ABIN7443305)

PDHX Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

PDHX antibody  (AA 222-471) PDHX antibody  (AA 222-471) PDHX antibody (AA 222-471) (ABIN7443338)

PDHX Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

PDHX antibody  (AA 1-300) PDHX antibody  (AA 1-300) PDHX antibody (AA 1-300) (ABIN7166903)

PDHX Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

PDHX Antibodies by Grade

Find PDHX Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PDHX Antibodies by Reactivity

Find PDHX Antibodies for a variety of species such as anti-Human PDHX, anti-Mouse PDHX, anti-Rat PDHX. The species listed below are among those available. Click on a link to go to the corresponding products.

PDHX Antibodies by Application

Find PDHX Antibodies validated for a specific application such as WB, IF (cc), IF (p), IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

PDHX Antibodies by Host

Find PDHX Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

PDHX Antibodies by Binding Specificity

Find PDHX Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PDHX Antibodies by Clonality

Find available monoclonal or polyclonal PDHX Antibodies. Click on a link to go to the corresponding products.

PDHX Antibodies by Clone

Find PDHX Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

PDHX Antibodies by Conjugate

Find PDHX Antibodies with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PDHX Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7443305
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7443338
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (4)
Cat. No. ABIN7166903
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN521742
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN948658
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), EIA
Validations
  • (3)
Cat. No. ABIN357414
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN185389
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN6145384
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IC
Validations
  • (2)
Cat. No. ABIN7306614
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN563534
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2856340
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7262258
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
  • (1)
Cat. No. ABIN5775964
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No. ABIN708221
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IP, ELISA
Validations
Cat. No. ABIN7118158
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PDHX Antibodies

Schild, Ruhs, Beiter, Zügel, Hudemann, Reimer, Krumholz-Wagner, Wagner, Keller, Eder, Krüger, Krüger, Braun, Nieß, Steinacker, Mooren: "Basal and exercise induced label-free quantitative protein profiling of m. vastus lateralis in trained and untrained individuals." in: Journal of proteomics, Vol. 122, pp. 119-32, (2015) (PubMed).

Murray, Gilkerson, Capaldi: "Quantitative proteomics: the copy number of pyruvate dehydrogenase is more than 10(2)-fold lower than that of complex III in human mitochondria." in: FEBS letters, Vol. 529, Issue 2-3, pp. 173-8, (2002) (PubMed).

Roche, Baker, Yan, Hiromasa, Gong, Peng, Dong, Turkan, Kasten: "Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms." in: Progress in nucleic acid research and molecular biology, Vol. 70, pp. 33-75, (2001) (PubMed).

Aliases for PDHX Antibodies

pyruvate dehydrogenase complex component X (PDHX) Antibodies
pyruvate dehydrogenase complex, component X (Pdhx) Antibodies
pyruvate dehydrogenase complex, component X (pdhx) Antibodies
pyruvate dehydrogenase complex component X L homeolog (pdhx.L) Antibodies
E3-binding protein (pdhX) Antibodies
pyruvate dehydrogenase complex component X (pdhx) Antibodies
Ac1164 Antibodies
AI481367 Antibodies
DDBDRAFT_0168431 Antibodies
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DDB_0168431 Antibodies
DDB_0230192 Antibodies
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E3BP Antibodies
E3bp Antibodies
MGC86218 Antibodies
OPDX Antibodies
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