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Browse our RPS6KB1 Proteins (RPS6KB1)

Full name:
Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 Proteins (RPS6KB1)
On are 13 Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) Proteins from 9 different suppliers available. Additionally we are shipping RPS6KB1 Antibodies (692) and RPS6KB1 Kits (33) and many more products for this protein. A total of 785 RPS6KB1 products are currently listed.
70kDa, 2610318I15Rik, 4732464A07Rik, AA959758, AI256796, AI314060, p70 S6KA, p70(S6K)-alpha, p70-alpha, p70-S6K, p70/85s6k, p70s6k, PS6K, S6K, S6K-beta-1, S6K1, STK14A
list all proteins Gene Name GeneID UniProt
RPS6KB1 6198 P23443
RPS6KB1 72508 Q8BSK8
RPS6KB1 83840 P67999

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RPS6KB1 Proteins (RPS6KB1) by Origin

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Top referenced RPS6KB1 Proteins

  1. Human RPS6KB1 Protein expressed in Baculovirus infected Insect Cells - ABIN593522 : Lustig, Ruas, Estall, Lo, Devarakonda, Laznik, Choi, Ono, Olsen, Spiegelman: Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase. in Genes & development 2011 (PubMed)

More Proteins for RPS6KB1 Interaction Partners

Human Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. These results indicated that p-p70S6K may participate in the invasion and metastasis in the development of ESCC and downregulation of the expression of p-p70S6K could improve the sensitivity of cells to rapamycin in ESCC.

  2. RPS6KB1 SNPs associated with susceptibility to multiple sclerosis in Iranian population.

  3. We found that S6K1 Iso-2 overexpression in cancer cells promoted cell growth and inhibited apoptosis, denotes its important role on NSCLC survival.

  4. S6K phosphorylation via the PI3K-PD1 pathway is involved in tau pathology in neurofibrillary tangles and abnormal neurites as well as actin pathology in Hirano bodies.

  5. Data suggest the role of the phospholipase C epsilon-Protein kinase D (show PRKD1 Proteins)-PEA15 (show PEA15 Proteins) protein-ribosomal S6 kinase-IkappaB-NF-kappa B (show NFKB1 Proteins) pathway in facilitating inflammation and inflammation-associated carcinogenesis in the colon.

  6. These results indicate that the inhibitory effect of rapamycin may be due mainly to increased p14 (show S100A9 Proteins), p15 (show CDKN2B Proteins), and p57 (show CDKN1C Proteins) expression via promoter demethylation and decreased mTOR (show FRAP1 Proteins) and p70S6K expression in ALL cell lines.

  7. The newly identified miR (show MLXIP Proteins)-195-RPS6KB1 axis partially illustrates the molecular mechanism of prostate cancer progression and represents a novel potential therapeutic target for prostate cancer treatment.

  8. eIF3 (show EIF3A Proteins) has a role in controlling cell size independently of S6K1-activity

  9. MiR (show MLXIP Proteins)-497 decreases cisplatin resistance in ovarian cancer cells by targeting mTOR (show FRAP1 Proteins)/P70S6K1.

  10. This study report that protein levels of the p70 S6 kinase (show PRKACB Proteins) was increased in Progressive Supranuclear Palsy and Corticobasal Degeneration brains.

Cow (Bovine) Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR, p70S6K, and ERK1/2.

  2. Lys (show LYZ Proteins), His, and Thr (show TRH Proteins) inhibited S6K1 phosphorylation in bovine mammary cells

Pig (Porcine) Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. This study found that, early in rotavirus enteritis, arginine has no impact on diarrhea but augments intestinal protein synthesis in part by p70(S6k) stimulation.

  2. There was no correlation of infarct size with expression or phosphorylation of p70S6K or GSK3beta in ischemic postconditioning.

Mouse (Murine) Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) interaction partners

  1. Data show that the formation of a tripartite ribosomal protein S6 kinase 1 (S6K1)-STING membrane protein-TANK-binding kinase 1 (TBK1 (show TBK1 Proteins)) complex was necessary for the activation of interferon regulatory factor-3 (IRF3 (show IRF3 Proteins)).

  2. Our study suggests that Ab25-35 induces autophagy and the PI3K/AKT (show AKT1 Proteins)/mTOR (show FRAP1 Proteins)/p70S6K pathway is involved in the process, which improves our understanding of the pathogenesis of Alzheimer's disease and provides an additional model for AD research

  3. Reducing S6K activity prevents accelerated axon growth induced by hyperactive mTOR (show FRAP1 Proteins) in vivo.

  4. targeting the S6K pathway selectively modifies the progression of pulmonary fibrosis in the subpleural compartment of the lung

  5. the Akt/mTOR/p70S6K pathway was activated in IgA nephropathy, and our findings suggested that rapamycin may represent a viable option for the treatment of IgA nephropathy

  6. The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration.

  7. in adult cardiac myocytes 4-hydroxy-trans-2-nonenal stimulates protein synthesis by activation of mTORC1-p70S6K-RPS6 (show RPS6 Proteins) signaling

  8. This is the first study highlighting the activation of S6K1 by palmitic acid as a common and novel mechanism by which its inhibition by oleic acid prevents endoplasmic reticulum stress, lipoapoptosis and insulin (show INS Proteins) resistance in hepatocytes.

  9. Our findings suggest that S6K1 signaling is not a general integrator of energy homeostasis in the mediobasal hypothalamus but has distinct roles in the regulation of glucose homeostasis

  10. Rotenone induction of hydrogen peroxide inhibits mTOR (show FRAP1 Proteins)-mediated S6K1 and 4E-BP1 (show EIF4EBP1 Proteins)/eIF4E (show EIF4E Proteins) pathways, resulting in caspase (show CASP3 Proteins)-dependent and -independent apoptosis in neuronal cells.

RPS6KB1 Protein Profile

Protein Summary

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Alternative names and synonyms associated with RPS6KB1

  • ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1)
  • ribosomal protein S6 kinase, polypeptide 1 (Rps6kb1)
  • 70kDa protein
  • 2610318I15Rik protein
  • 4732464A07Rik protein
  • AA959758 protein
  • AI256796 protein
  • AI314060 protein
  • p70 S6KA protein
  • p70(S6K)-alpha protein
  • p70-alpha protein
  • p70-S6K protein
  • p70/85s6k protein
  • p70s6k protein
  • PS6K protein
  • S6K protein
  • S6K-beta-1 protein
  • S6K1 protein
  • STK14A protein

Protein level used designations for RPS6KB1

p70 S6 kinase, alpha , ribosomal protein S6 kinase I , ribosomal protein S6 kinase beta-1 , serine/threonine kinase 14 alpha , serine/threonine-protein kinase 14A , 70 kDa ribosomal protein S6 kinase 1 , P70S6K1 , S6K , S6K-beta-1 , p70 S6 kinase alpha , p70(S6K)-alpha , p70-S6K 1 , p70S6K , ribosomal protein S6 kinase polypeptide 1 , G3 serine/threonine kinase , P70S6K , S6K1 , p70 S6K-alpha , p70 S6KA , p70 ribosomal S6 kinase alpha , ribosomal protein S6 kinase, 70kD, polypeptide 1 , S6 kinase , ribosomal protein S6 kinase, 70kDa, polypeptide 1

100057481 Equus caballus
6198 Homo sapiens
404181 Bos taurus
417637 Gallus gallus
480580 Canis lupus familiaris
100127158 Sus scrofa
100009260 Oryctolagus cuniculus
72508 Mus musculus
83840 Rattus norvegicus
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