RPS6KB1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2731182

Product Details

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This RPS6KB1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human RPS6KB1 / STK14A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Alternative Name: Rps6kb1,stk14a (RPS6KB1 Products)

Synonyms: PS6K Protein, S6K Protein, S6K-beta-1 Protein, S6K1 Protein, STK14A Protein, p70 S6KA Protein, p70(S6K)-alpha Protein, p70-S6K Protein, p70-alpha Protein, 10539 Protein, 7084 Protein, CG10539 Protein, DS6K Protein, Dmel\\CG10539 Protein, Dp70S6k Protein, Dp70[s6k] Protein, Dp70s6k Protein, S6k Protein, dS6K Protein, dS6k Protein, dp70[S6k] Protein, dp70s6k Protein, dps6k Protein, ds6k Protein, fs(3)07084 Protein, l(3)07084 Protein, p70 S6K Protein, p70/S6K Protein, p70S6K Protein, p70[S6 kinase] Protein, p70[S6K] Protein, p70[S6k] Protein, p70[S6kinase] Protein, p70s6K Protein, s6k Protein, s6k11 Protein, 2610318I15Rik Protein, 4732464A07Rik Protein, 70kDa Protein, AA959758 Protein, AI256796 Protein, AI314060 Protein, p70/85s6k Protein, p70s6k Protein, p70s6k-A Protein, p70-s6k Protein, ps6k Protein, rps6kb1 Protein, rps6kb1-A Protein, s6K1 Protein, stk14a Protein, fc51h01 Protein, wu:fc51h01 Protein, zgc:55713 Protein, ribosomal protein S6 kinase B1 Protein, Ribosomal protein S6 kinase Protein, ribosomal protein S6 kinase, polypeptide 1 Protein, ribosomal protein S6 kinase B1 L homeolog Protein, ribosomal protein S6 kinase B1 S homeolog Protein, ribosomal protein S6 kinase b, polypeptide 1b Protein, RPS6KB1 Protein, S6k Protein, Rps6kb1 Protein, rps6kb1.L Protein, rps6kb1.S Protein, rps6kb1b Protein

Background: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Molecular Weight: 59 kDa

NCBI Accession: NP_003152

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effect