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Browse our ACER2 Proteins (ACER2)

Full name:
Alkaline Ceramidase 2 Proteins (ACER2)
On are 3 Alkaline Ceramidase 2 (ACER2) Proteins from 2 different suppliers available. Additionally we are shipping ACER2 Antibodies (12) and many more products for this protein. A total of 17 ACER2 products are currently listed.
2410116I05Rik, ALKCDase2, Asah3l, CRG-L1, maCER2
list all proteins Gene Name GeneID UniProt
ACER2 340485 Q5QJU3
ACER2 230379 Q8VD53
Rat ACER2 ACER2 313339  

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ACER2 Proteins (ACER2) by Origin

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More Proteins for ACER2 Interaction Partners

Human Alkaline Ceramidase 2 (ACER2) interaction partners

  1. Results suggest that the ACER2/sphingosine pathway mediates programmed cell death in response to DNA damage through ROS (show ROS1 Proteins) production.

  2. c-Src (show SRC Proteins)-mediated signal positively regulates ACER activity in a Ca2 (show CA2 Proteins)+-independent manner.

  3. Results suggest that up-regulation of the ACER2/DHS pathway mediates the cytotoxicity of 4-HPR in tumor cells and that up-regulating or activating ACER2 may improve the anti-cancer activity of 4-HRR and other DHC-inducing agents.

  4. ACER2 has broad substrate specificity and requires Ca(2 (show CA2 Proteins)+) for its activity; ACER2 has the cytosolic C terminus and luminal N terminus, which are essential for its activity, correct cellular localization, and regulation for protein glycosylation

  5. ACER2/sphingosine pathway plays an important role in regulating beta1 maturation and cell adhesion mediated by beta1 integrins

ACER2 Protein Profile

Protein Summary

The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006

Alternative names and synonyms associated with ACER2

  • alkaline ceramidase 2 (ACER2)
  • alkaline ceramidase 2 (acer2)
  • alkaline ceramidase 2 (LOC100337862)
  • alkaline ceramidase 2 (Acer2)
  • 2410116I05Rik protein
  • ALKCDase2 protein
  • Asah3l protein
  • CRG-L1 protein
  • maCER2 protein

Protein level used designations for Alkaline Ceramidase 2 Proteins (ACER2)

alkaline ceramidase 2 , N-acylsphingosine amidohydrolase 3-like , putative protein, with at least 4 transmembrane domains, of eukaryotic origin (5H174) , alkCDase 2 , alkaline CDase 2 , ceramide hydrolase , haCER2 , cancer related gene-liver 1 (CRG-L1) , cancer-related gene liver 1 protein

481553 Canis lupus familiaris
779231 Xenopus laevis
100337862 Oryctolagus cuniculus
465015 Pan troglodytes
540732 Bos taurus
549870 Xenopus (Silurana) tropicalis
100528685 Ictalurus punctatus
340485 Homo sapiens
230379 Mus musculus
313339 Rattus norvegicus
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