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ACLY Proteins

(ATP Citrate Lyase (ACLY))
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
ACLY Protein (AA 4-265) (His tag) ACLY Protein (AA 4-265) (His tag) ACLY Protein (AA 4-265) (His tag) (ABIN7121924)

ACLY Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

ACLY Protein (His tag) (ABIN7194322)

ACLY Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE.

ACLY Protein (AA 1-1101) (Strep Tag) (ABIN3088222)

ACLY Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, ELISA, SDS

ACLY Proteins by Origin

Find ACLY Proteins for a variety of species such as anti-Human ACLY, anti-Mouse ACLY. The species listed below are among those available. Click on a link to go to the corresponding products.

ACLY Proteins by Source

Here you will find ACLY Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

ACLY Proteins by Protein Type

Here you can find ACLY Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

ACLY Proteins by Application

Find ACLY Proteins validated for a specific application such as ELISA, WB, SDS, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ACLY Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121924
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
Cat. No. ABIN7194322
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3088222
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136775
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2715038
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our ACLY Proteins

Chen, Qian, He, Zhao, Toral-Barza, Shi, Zhang, Wu, Yu: "mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer." in: Oncotarget, Vol. 7, Issue 18, pp. 25224-40, (2018) (PubMed).

Aliases for ACLY Proteins

ATP citrate lyase (ACLY) Proteins
ATP citrate lyase S homeolog (acly.S) Proteins
ATP-citrate synthase (LOC587157) Proteins
ATP citrate lyase (acly) Proteins
ATP citrate lyase (ATPCL) Proteins
ATP-citrate synthase (LOC5564509) Proteins
citrate synthase, mitochondrial (CpipJ_CPIJ010291) Proteins
ATP-citrate synthase (Bm1_26245) Proteins
atp-citrate synthase (ACL) Proteins
ATP citrate lyase (Acly) Proteins
ATP citrate lyase a (aclya) Proteins
A730098H14Rik Proteins
ACL Proteins
ACLY Proteins
acly Proteins
anon-WO0140519.179 Proteins
ATPCL Proteins
AW538652 Proteins
BcDNA:LD21334 Proteins
cb722 Proteins
CG8322 Proteins
CLATP Proteins
Clatp Proteins
dATPCL Proteins
DDBDRAFT_0205389 Proteins
DDBDRAFT_0235360 Proteins
DDB_0205389 Proteins
DDB_0235360 Proteins
DmATPCL Proteins
Dmel\\CG8322 Proteins
l(2)01466 Proteins
l(2)k09217 Proteins
n(2)k09217 Proteins
zgc:92008 Proteins
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