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ACER1 Proteins

(Alkaline Ceramidase 1 (ACER1))

Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al., 2006 [PubMed 16477081]\; Sun et al., 2008 [PubMed 17713573]).[supplied by OMIM, Jul 2010].

recommended

ACER1 Protein (AA 1-264) (Strep Tag) (ABIN3104294)

Crystallography grade ACER1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS

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recommended

ACER1 Protein (AA 1-273) (Strep Tag) (ABIN3126824)

Crystallography grade ACER1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS

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recommended

ACER1 Protein (Myc-DYKDDDDK Tag) (ABIN2714568)

ACER1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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ACER1 Proteins by Grade

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ACER1 Proteins by Origin

Find ACER1 Proteins for a variety of species such as anti-Human ACER1, anti-Mouse ACER1. The species listed below are among those available. Click on a link to go to the corresponding products.

ACER1 Proteins by Source

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ACER1 Proteins by Protein Type

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ACER1 Proteins by Application

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Popular ACER1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

ACER1 Protein (AA 1-264) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3104294

Quantity 1 mg

Datasheet Datasheet

ACER1 Protein (AA 1-273) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3126824

Quantity 1 mg

Datasheet Datasheet

ACER1 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2714568

Quantity 20 μg

Datasheet Datasheet

Aliases for ACER1 Proteins

alkaline ceramidase 1 (ACER1) Proteins
alkaline ceramidase 1 (acer1) Proteins
alkaline ceramidase 1 (Acer1) Proteins
2310024P18Rik Proteins
AI662009 Proteins
ALKCDase1 Proteins
Alkcdase1 Proteins
ASAH3 Proteins
asah3 Proteins
Asah3 Proteins
Cer1 Proteins
zgc:110285 Proteins

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ACER1 Proteins by Grade

ACER1 Proteins by Origin

ACER1 Proteins by Source

ACER1 Proteins by Protein Type

ACER1 Proteins by Application

Popular ACER1 Proteins

Aliases for ACER1 Proteins

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