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ACER1 Proteins

(Alkaline Ceramidase 1 (ACER1))
Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al., 2006 [PubMed 16477081]\; Sun et al., 2008 [PubMed 17713573]).[supplied by OMIM, Jul 2010].
ACER1 Protein (AA 1-273) (Strep Tag) (ABIN3126824)

ACER1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS

ACER1 Protein (AA 1-264) (Strep Tag) (ABIN3104294)

ACER1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS

ACER1 Protein (Myc-DYKDDDDK Tag) ACER1 Protein (Myc-DYKDDDDK Tag) ACER1 Protein (Myc-DYKDDDDK Tag) (ABIN2714568)

ACER1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

ACER1 Proteins by Origin

Find ACER1 Proteins for a variety of species such as anti-Human ACER1, anti-Mouse ACER1. The species listed below are among those available. Click on a link to go to the corresponding products.

ACER1 Proteins by Source

Here you will find ACER1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

ACER1 Proteins by Protein Type

Here you can find ACER1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

ACER1 Proteins by Application

Find ACER1 Proteins validated for a specific application such as ELISA, SDS, WB, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ACER1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3126824
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3104294
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2714568
Quantity 20 μg
Datasheet Datasheet

Aliases for ACER1 Proteins

alkaline ceramidase 1 (ACER1) Proteins
alkaline ceramidase 1 (acer1) Proteins
alkaline ceramidase 1 (Acer1) Proteins
2310024P18Rik Proteins
AI662009 Proteins
ALKCDase1 Proteins
Alkcdase1 Proteins
ASAH3 Proteins
asah3 Proteins
Asah3 Proteins
Cer1 Proteins
zgc:110285 Proteins
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