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Browse our Coagulation Factor III (thromboplastin, Tissue Factor) Proteins (F3)

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Coagulation Factor III (thromboplastin, Tissue Factor) Proteins (F3)
On are 40 Coagulation Factor III (thromboplastin, Tissue Factor) (F3) Proteins from 13 different suppliers available. Additionally we are shipping Coagulation Factor III (thromboplastin, Tissue Factor) Antibodies (248) and Coagulation Factor III (thromboplastin, Tissue Factor) Kits (89) and many more products for this protein. A total of 388 Coagulation Factor III (thromboplastin, Tissue Factor) products are currently listed.
AA409063, CD142, Cf-3, Cf3, f3, TF, TFA
list all proteins Gene Name GeneID UniProt
F3 14066 P20352
F3 2152 P13726
F3 25584  

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Coagulation Factor III (thromboplastin, Tissue Factor) Proteins (F3) by Origin

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Top referenced Coagulation Factor III (thromboplastin, Tissue Factor) Proteins

  1. Human F3 Protein expressed in Escherichia coli (E. coli) - ABIN1098373 : Bogdanov, Balasubramanian, Hathcock, Vele, Lieb, Nemerson: Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein. in Nature medicine 2003 (PubMed)
    Show all 2 references for ABIN1098373

  2. Mouse (Murine) F3 Protein expressed in Human Cells - ABIN2007770 : Kinev, Roubey: Tissue factor in the antiphospholipid syndrome. in Lupus 2008 (PubMed)

More Proteins for Coagulation Factor III (thromboplastin, Tissue Factor) Interaction Partners

Mouse (Murine) Coagulation Factor III (thromboplastin, Tissue Factor) (F3) interaction partners

  1. Thrombin (show F2 Proteins)-independent contribution of tissue factor to inflammation and cardiac hypertrophy in a mouse model of sickle cell disease.

  2. These findings reveal a novel biological function and mechanism of the protein C (show PROC Proteins) pathway in which protein S and the aPC (show APC Proteins)-cleaved form of fV are cofactors for anti-inflammatory cell signaling by aPC (show APC Proteins) in the context of endotoxemia and infection

  3. Lung epithelial tissue factor regulates alveolar procoagulant activity and permeability in acute lung injury.

  4. PGE2 increases both TF expression and activity through the regulation of the EP1 (show PTGER1 Proteins)/SIRT1 (show SIRT1 Proteins) pathway.

  5. Fas (show FAS Proteins)-initiated, caspase-3 (show CASP3 Proteins)-dependent hepatocyte apoptosis increases tissue factor procoagulant activity through a mechanism involving phosphatidylserine externalization.

  6. Heme promotes tissue factor-dependent coagulation activation and induces tissue factor expression on leukocytes in vivo.

  7. TF is essential for the development of pericyte coverage of tumor microvessels and aPL (show FASL Proteins)-induced tumor cell expression of chemokine ligand 2 (show CXCL2 Proteins), a mediator of pericyte recruitment

  8. Alternatively spliced tissue factor promotes plaque angiogenesis through the activation of hypoxia-inducible factor-1alpha and vascular endothelial growth factor signaling.

  9. Klkb1 (show KLKB1 Proteins)(-/-) mice have a novel mechanism for thrombosis protection in addition to reduced contact activation. This pathway arises when bradykinin delivery to vasculature is compromised and mediated by increased receptor Mas (show MAS1 Proteins), prostacyclin, Sirt1 (show SIRT1 Proteins), and KLF4 (show KLF4 Proteins)

  10. study provides a novel mechanism for the posttranscriptional regulation of TF expression, indicating that this is selectively regulated by PARP-14.

Human Coagulation Factor III (thromboplastin, Tissue Factor) (F3) interaction partners

  1. Hypoxia increased the expression of TF in human podocytes NF-kappaB (show NFKB1 Proteins) dependently. TF may have a critical role in the hypoxic podocyte injury.

  2. These results reveal a functional link between VWF (show VWF Proteins) and TF under whole blood flow conditions, in which surface-immobilized TF and VWF (show VWF Proteins) mutually contribute to mural thrombus formation, which is essential for normal hemostasis. By contrast, TF circulating in blood may be involved in systemic hypercoagulability, as seen in sepsis caused by severe microbial infection, in which neutrophil inflammatory responses may be active.

  3. TF expression significantly correlated with levels of CRP (show CRP Proteins), TNF-alpha (show TNF Proteins) and MCP-1 (show CCL2 Proteins). These factors may play an important role in the development of chronic thromboembolic pulmonary hypertension.

  4. Microvesicle-associated tissue factor procoagulant activity, but not plasma TF antigen, may provide valuable additional information for the diagnostic work-up of women with suspected ovarian cancer.

  5. stimulated von Willebrand factor (show VWF Proteins) secretion by umbilical vein endothelial cells

  6. Circulating FVII (show F7 Proteins), FVIIa and TFPI (show TFPI Proteins) were significantly elevated in women with severe preeclampsia in the absence of comparable changes in plasma TF levels.

  7. The data obtained indicate that active tissue factor, TF is present in membrane microparticles produced in vitro by endothelial cells, monocytes, and THP-1 cells, but not in microparticles derived from granulocytes and platelets.

  8. Results indicate that granulocyte-colony stimulating factor receptor, tissue factor, and vascular endothelial growth factor receptor bound vascular endothelial growth factor expression as well as their co-expression might influence breast cancer biology.

  9. the actin-binding protein (show KPTN Proteins) filamin-A (show FLNA Proteins) has a critical role in incorporation of Tissue factor into extracellular vesicles and secretion of extracellular vesicles from ovarian cancer cells exposed to hypoxia

  10. Tissue factor uptake by platelets involves the scavenger receptor CD36 (show CD36 Proteins), SERT (show SLC6A4 Proteins) and engages PI3-Kinase (show PIK3CA Proteins) activation and cytoskeletal assembly.

Rabbit Coagulation Factor III (thromboplastin, Tissue Factor) (F3) interaction partners

  1. Arterial (18)F-fluorodeoxyglucose uptake reflects balloon catheter-induced thrombus formation and tissue factor expression via nuclear factor-kappaB in rabbit atherosclerotic lesions.

  2. Polycations could present a new class of anticoagulants with such unique upstream downregulation of blood coagulation, selectively blocking tissue factor-dependent factor VII (show TH Proteins) activation.

  3. Upregulated TF expression and increased plasma TF level during reperfusion period, reduced plasma TFPI-1 (show TFPI Proteins) level during reperfusion period.

  4. lectin-like oxidized LDL receptor (show OLR1 Proteins) Oxidized low-density lipoprotein receptor (show LDLR Proteins) 1expression appears to be closely associated with tissue factor expression, apoptotic events and morphological vulnerability in atherosclerotic lesions

Pig (Porcine) Coagulation Factor III (thromboplastin, Tissue Factor) (F3) interaction partners

  1. Tissue factor expression on porcine neonatal islet cell clusters is an important initiator of instant blood-mediated inflammatory reaction in islet xenotransplantation.

  2. Prolonged clopidogrel treatment reduced coronary tissue factor (TF) expression and tended to reduce the blood TF level post-PCI (show SERPINA5 Proteins), thus possibly modulating the risk of late thrombosis.

  3. Procoagulant porcine tissue factor is induced in primary pig aortic endothelial cells only by fresh human plasma, and not by heat-inactivated plasma.

  4. myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor cyclo-oxygenase-2, monocyte chemoattractant protein-1 (show CCL2 Proteins) and CRP (show CRP Proteins)

Coagulation Factor III (thromboplastin, Tissue Factor) (F3) Protein Profile

Protein Summary

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with Coagulation Factor III (thromboplastin, Tissue Factor) (F3)

  • coagulation factor IIIa (f3a)
  • tissue factor (tf)
  • coagulation factor III (F3)
  • coagulation factor III (thromboplastin, tissue factor) (F3)
  • AA409063 protein
  • CD142 protein
  • Cf-3 protein
  • Cf3 protein
  • f3 protein
  • TF protein
  • TFA protein

Protein level used designations for F3

TFa , coagulation factor III , thromboplastin , tissue factor , TF , brain tissue factor , coagulation factor 3

567257 Danio rerio
100136035 Oncorhynchus mykiss
14066 Mus musculus
100135463 Cavia porcellus
280686 Bos taurus
2152 Homo sapiens
100009127 Oryctolagus cuniculus
25584 Rattus norvegicus
490153 Canis lupus familiaris
396677 Sus scrofa
429084 Gallus gallus
101118918 Ovis aries
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