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Titin Proteins

(Titin (TTN))
This gene encodes a large abundant protein of striated muscle. The product of this gene is divided into two regions, a N-terminal I-band and a C-terminal A-band. The I-band, which is the elastic part of the molecule, contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline, glutamate, valine and lysine. The A-band, which is thought to act as a protein-ruler, contains a mixture of immunoglobulin and fibronectin repeats, and possesses kinase activity. An N-terminal Z-disc region and a C-terminal M-line region bind to the Z-line and M-line of the sarcomere, respectively, so that a single titin molecule spans half the length of a sarcomere. Titin also contains binding sites for muscle associated proteins so it serves as an adhesion template for the assembly of contractile machinery in muscle cells. It has also been identified as a structural protein for chromosomes. Alternative splicing of this gene results in multiple transcript variants. Considerable variability exists in the I-band, the M-line and the Z-disc regions of titin. Variability in the I-band region contributes to the differences in elasticity of different titin isoforms and, therefore, to the differences in elasticity of different muscle types. Mutations in this gene are associated with familial hypertrophic cardiomyopathy 9, and autoantibodies to titin are produced in patients with the autoimmune disease scleroderma. [provided by RefSeq, Feb 2012].
Titin Protein (TTN) (AA 14257-14543) (His tag) Titin Protein (TTN) (AA 14257-14543) (His tag) Titin Protein (TTN) (AA 14257-14543) (His tag) (ABIN7125403)

TTN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

Titin Protein (TTN) (AA 1-305) (GST tag) Titin Protein (TTN) (AA 1-305) (GST tag) Titin Protein (TTN) (AA 1-305) (GST tag) (ABIN1324073)

TTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

Titin Protein (TTN) (AA 1-110) (GST tag) Titin Protein (TTN) (AA 1-110) (GST tag) Titin Protein (TTN) (AA 1-110) (GST tag) (ABIN1324075)

TTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

Titin Proteins by Origin

Find Titin Proteins for a variety of species such as anti-Human Titin, anti-Mouse Titin. The species listed below are among those available. Click on a link to go to the corresponding products.

Titin Proteins by Source

Here you will find Titin Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Titin Proteins by Protein Type

Here you can find Titin Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Titin Proteins by Application

Find Titin Proteins validated for a specific application such as WB, ELISA, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Titin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125403
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324073
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324075
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324077
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423204
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7394549
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5712956
Quantity 100 μg
Datasheet Datasheet

Aliases for Titin Proteins

titin (TTN) Proteins
titin (Ttn) Proteins
titin (titin) Proteins
titin (TTNLOC100620261) Proteins
1100001C23Rik Proteins
2310036G12Rik Proteins
2310057K23Rik Proteins
2310074I15Rik Proteins
AF006999 Proteins
AV006427 Proteins
CMD1G Proteins
CMH9 Proteins
CMPD4 Proteins
D330041I19Rik Proteins
D830007G01Rik Proteins
EOMFC Proteins
HMERF Proteins
L56 Proteins
LGMD2J Proteins
mdm Proteins
MYLK5 Proteins
shru Proteins
TMD Proteins
UNC-22 Proteins
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