Browse our anti-NLRP1 (NLRP1) Antibodies

Full name:
anti-NLR Family, Pyrin Domain Containing 1 Antibodies (NLRP1)
On are 75 NLR Family, Pyrin Domain Containing 1 (NLRP1) Antibodies from 18 different suppliers available. Additionally we are shipping NLRP1 Kits (4) and and many more products for this protein. A total of 87 NLRP1 products are currently listed.
CARD7, CIDED, CLR17.1, DEFCAP, DEFCAP-L/S, Gm14, Gm15, NAC, NALP1, Nalp1a, Nlrp1, PP1044, SLEV1, VAMAS1
list all antibodies Gene Name GeneID UniProt
NLRP1 360557  
NLRP1 22861 Q9C000
NLRP1 195046  

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Top referenced anti-NLRP1 Antibodies

  1. Human Polyclonal NLRP1 Primary Antibody for ICC, IF - ABIN4890403 : Fahy, Exline, Gavrilin, Bhatt, Besecker, Sarkar, Hollyfield, Duncan, Nagaraja, Knatz, Hall, Wewers: Inflammasome mRNA expression in human monocytes during early septic shock. in American journal of respiratory and critical care medicine 2008 (PubMed)
    Show all 5 references for 4890403

  2. Human Polyclonal NLRP1 Primary Antibody for IF, IHC (p) - ABIN303286 : Hlaing, Guo, Dilley, Loussia, Morrish, Shi, Vincenz, Ward: Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 references for 303286

  3. Human Monoclonal NLRP1 Primary Antibody for ICC, IF - ABIN4340089 : Kummer, Broekhuizen, Everett, Agostini, Kuijk, Martinon, van Bruggen, Tschopp: Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007 (PubMed)

More Antibodies against NLRP1 Interaction Partners

Human NLR Family, Pyrin Domain Containing 1 (NLRP1) interaction partners

  1. NLRP1 promotes melanoma growth by enhancing inflammasome activation and suppressing apoptotic pathways.

  2. Two new mutations in NLRP1 (c.3641C>G, p.Pro1214Arg and c.2176C>T; p.Arg726Trp) were found to cause a new autoinflammatory syndrome, NLRP1-associated autoinflammation with arthritis and dyskeratosis.

  3. Th17 micro-milieu via IL-17A (show IL17A Antibodies) regulates NLRP1-dependent CASP5 (show CASP5 Antibodies) activity in psoriatic skin autoinflammation.

  4. HO-1 (show HMOX1 Antibodies) inhibited expression of activating transcription factor 4 (ATF4 (show ATF4 Antibodies)), which is a transcription factor regulating NLRP1 expression

  5. Simvastatin intake in peripheral arterial disease patients increases in vitro reactivity of NLRP1 inflammasome gene expression in endothelial cells.

  6. these findings establish a group of non-fever inflammasome disorders, uncover an unexpected auto-inhibitory function for the pyrin (show MEFV Antibodies) domain, and provide the first genetic evidence linking NLRP1 to skin inflammatory syndromes and skin cancer predisposition.

  7. The NLRP3 (show NLRP3 Antibodies) and NLRP1 inflammasomes are activated in Alzheimer's disease

  8. NLRP1 inflammasome is activated by extracellular acidosis through ASIC1a (show ACCN2 Antibodies) signal pathway.

  9. Nlrp1 inflammasome is downregulated in trauma patients

  10. Human central Nervous System neurons express NLRP1 inflammasomes, which activate Casp1 (show CASP1 Antibodies) and subsequently Casp6 (show CASP6 Antibodies). Casp1 (show CASP1 Antibodies) activation generates interleukin-1-beta (show IL1B Antibodies)-mediated neuroinflammation and Casp6 (show CASP6 Antibodies) activation causes axonal degeneration.

Mouse (Murine) NLR Family, Pyrin Domain Containing 1 (NLRP1) interaction partners

  1. The findings indicate that NLRP1 inflammasome activation does not significantly contribute to acute neural injury in the murine model of moderate CCI injury.

  2. the aim of this study was to evaluate the effects of chronic dexamethasone (DEX) treatment on nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 1 (show PYDC1 Antibodies) (NLRP-1) inflammasome in male mice.

  3. NLRP1 is an innate immune sensor that functions in the context of metabolic stress to produce IL-18 (show IL18 Antibodies), preventing obesity and metabolic syndrome.

  4. these data identify NLRP1 as an essential mediator of the host immune response during IBD and cancer.

  5. Data show that eicosanoid 15-deoxy-Delta(12,14)-PGJ2 (15d-PGJ2) and related cyclopentenone PGs inhibit caspase-1 (show CASP1 Antibodies) activation by the NLR (show CXCR5 Antibodies) family leucine-rich repeat protein (show LRRC10 Antibodies) (NLRP)1 and NLRP3 (show NLRP3 Antibodies) inflammasomes.

  6. The NOD-like receptor NLRP1a/Caspase-1 (show CASP1 Antibodies) pathway is the best candidate to mediate the parasite-induced cell death.

  7. Caspase-8 (show CASP8 Antibodies) promotes NLRP1/NLRP3 (show NLRP3 Antibodies) inflammasome activation and IL-1beta (show IL1B Antibodies) production in acute glaucoma.

  8. These findings reveal Toxoplasma gondii as a novel activator of the NLRP1 and NLRP3 (show NLRP3 Antibodies) inflammasomes in vivo and establish a role for these sensors in host resistance to toxoplasmosis.

  9. Arsenicals, including arsenic trioxide and sodium arsenite, inhibited activation of the NLRP1, NLRP3 (show NLRP3 Antibodies), and NAIP5/NLRC4 (show NLRC4 Antibodies) inflammasomes.

  10. the NLRP1 and NLRP3 (show NLRP3 Antibodies) inflammasomes have a major role in neuronal cell death and behavioral deficits in stroke.

NLRP1 Antigen Profile

Antigen Summary

This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Alternative names and synonyms associated with NLRP1

  • NLR family, pyrin domain containing 1A (Nlrp1a) antibody
  • NLR family, pyrin domain containing 1 (NLRP1) antibody
  • CARD7 antibody
  • CIDED antibody
  • CLR17.1 antibody
  • DEFCAP antibody
  • DEFCAP-L/S antibody
  • Gm14 antibody
  • Gm15 antibody
  • NAC antibody
  • NALP1 antibody
  • Nalp1a antibody
  • Nlrp1 antibody
  • PP1044 antibody
  • SLEV1 antibody
  • VAMAS1 antibody

Protein level used designations for NLRP1

NACHT, leucine rich repeat and PYD containing 1 , NLR family protein 1 , NLR family, pyrin domain containing 1 , resistant anthrax lethal toxin , NACHT, LRR and PYD domains-containing protein 1 , NLR family pyrin domain containing 1 , NACHT, LRR and PYD containing protein 1 , NACHT, leucine rich repeat and PYD (pyrin domain) containing 1 , caspase recruitment domain protein 7 , caspase recruitment domain-containing protein 7 , death effector filament-forming Ced-4-like apoptosis protein , nucleotide-binding domain and caspase recruitment domain , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1 , NACHT/LRR/pyrin domain-containing protein 1 , caspase recruitment domain protein

360557 Rattus norvegicus
489449 Canis lupus familiaris
721648 Macaca mulatta
100412129 Callithrix jacchus
100481297 Ailuropoda melanoleuca
100607186 Nomascus leucogenys
22861 Homo sapiens
195046 Mus musculus
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