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Browse our anti-ROBO1 (ROBO1) Antibodies

Full name:
anti-Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila) Antibodies (ROBO1)
On www.antibodies-online.com are 99 Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila) (ROBO1) Antibodies from 19 different suppliers available. Additionally we are shipping ROBO1 Proteins (9) and ROBO1 Kits (5) and many more products for this protein. A total of 118 ROBO1 products are currently listed.
Synonyms:
AW494633, AW742721, DMT-1, DUTT1, Gm310, MGC122264, ROBO1, roundabout, roundabout-1, SAX3
list all antibodies Gene Name GeneID UniProt
ROBO1 24906 O55006
ROBO1 19876 O89026
ROBO1 6091 Q9Y6N7

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Top referenced anti-ROBO1 Antibodies

  1. Dog (Canine) Polyclonal ROBO1 Primary Antibody for EIA, IHC (p) - ABIN401279 : Latil, Chêne, Cochant-Priollet, Mangin, Fournier, Berthon, Cussenot: Quantification of expression of netrins, slits and their receptors in human prostate tumors. in International journal of cancer. Journal international du cancer 2002 (PubMed)
    Show all 6 references for ABIN401279

  2. Human Polyclonal ROBO1 Primary Antibody for ELISA, WB - ABIN251549 : Hannula-Jouppi, Kaminen-Ahola, Taipale, Eklund, Nopola-Hemmi, Kääriäinen, Kere: The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia. in PLoS genetics 2005 (PubMed)

  3. Mouse (Murine) Polyclonal ROBO1 Primary Antibody for ELISA, WB - ABIN185724 : Andrews, Liapi, Plachez, Camurri, Zhang, Mori, Murakami, Parnavelas, Sundaresan, Richards: Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain. in Development (Cambridge, England) 2006 (PubMed)

  4. Human Polyclonal ROBO1 Primary Antibody for IP, IHC - ABIN1043879 : Li, Wang, Chen, Liang: [Auditory neuropathy in children(analysis of 14 cases)]. in Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 2005 (PubMed)

  5. Human Polyclonal ROBO1 Primary Antibody for WB - ABIN265227 : Dallol, Forgacs, Martinez, Sekido, Walker, Kishida, Rabbitts, Maher, Minna, Latif: Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers. in Oncogene 2002 (PubMed)

More Antibodies against ROBO1 Interaction Partners

Zebrafish Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila) (ROBO1) interaction partners

  1. These results demonstrate a key role for Robo-Slit signaling in vertebrate longitudinal axon guidance; Robo1 and Robo3 (show ROBO3 Antibodies) restricted the extent of defasciculation of the tract of the postoptic commissure.

Mouse (Murine) Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila) (ROBO1) interaction partners

  1. restoration of miR (show MLXIP Antibodies)-218 inhibited retinal angiogenesis via targeting Robo1. MiR (show MLXIP Antibodies)-218 contributed to the inhibition of retinal angiogenesis and miR (show MLXIP Antibodies)-218 might be a new therapeutic target for preventing retinal neovascularization..

  2. Robo1-Slit2 interaction required for pathfinding mechanism essential to establish the functionally important habenulo-interpeduncular connection.

  3. FLRT3 (show FLRT3 Antibodies) is a Robo1 coreceptor in developing axons.

  4. Slit2 (show SLIT2 Antibodies)/Robo1 signaling promotes intestinal tumorigenesis through Src (show SRC Antibodies)-mediated activation of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

  5. Robo1/2 regulate follicle atresia through manipulating granulosa cell apoptosis in mice

  6. Roundabout receptor (Robo) genes are expressed in pulmonary neuroendocrine cells (PNECs), a rare, innervated epithelial population. Robo inactivation in mouse lung results in an inability of PNECs to cluster into sensory organoids and triggers increased neuropeptide production upon exposure to air.

  7. Slit2 (show SLIT2 Antibodies) signaling through Robo1 and Robo2 (show ROBO2 Antibodies) has a role in retinal neovascularization

  8. Data indicate the roles of Slit1 (show SLIT1 Antibodies)/Robo1 and Netrin1/DCC (show DCC Antibodies) signals in positioning motor neuron cell bodies.

  9. This study demonistrated that significant increase of interneurons in the cortices of Robo1-/- mice, implicate Robo1 in the regulation of progenitor cell dynamics in the developing forebrain.

  10. we report that Robo1 plays an important role in guiding olfactory sensory neurons in the mouse olfactory system during development.

Human Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila) (ROBO1) interaction partners

  1. High Slit2 expression is associated with glioma.

  2. ROBO1 mediated the inhibitory effect of miR (show MLXIP Antibodies)-218 on angiogenesis in gastric cancer.

  3. Results indicate the importance of SLIT2 (show SLIT3 Antibodies)-ROBO1-CDC42 (show CDC42 Antibodies) signaling pathway in predicting tumor progression.

  4. We postulate that Robo1 promotes tumor invasion partly by the upregulation of MMP2 (show MMP2 Antibodies) after activation of PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway. Notably, Slit2 (show SLIT3 Antibodies) knockdown caused the upregulation of Robo1 expression both at the mRNA and protein levels. Thus, the stimulatory effects of Slit2 (show SLIT3 Antibodies) knockdown on tumor progression can be ascribed, at least in part, to the upregulation of Robo1 and its positive role in tumor progression.

  5. ROBO1 deletion in a putative transcriptional regulatory region

  6. Over-expression of miR (show MLXIP Antibodies)-218 in glioma cells may inhibit the proliferation and tumorigenicity through targeting Robo1, suggesting that miR (show MLXIP Antibodies)-218 could be a potential target for developing therapies in treating glioma.

  7. Significantly increased serum Slit2 (show SLIT3 Antibodies) levels and hepatic expression of Slit2 (show SLIT3 Antibodies) and Robo1 were observed in patients with liver fibrosis.

  8. our findings indicated that Slit2 (show SLIT3 Antibodies)/Robo1 axis possibly be regarded as a significant clinical parameter for predicting brain metastasis in breast cancer patients.

  9. miR (show MLXIP Antibodies)-29a markedly inhibits the protein expression of Robo1 in mesenchymal stem cells.

  10. A SLIT2 (show SLIT3 Antibodies)/ROBO1 signaling circuit as a key regulatory mechanism.

ROBO1 Antigen Profile

Antigen Summary

Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with ROBO1

  • roundabout homolog 1 (robo1) antibody
  • roundabout, axon guidance receptor, homolog 1 (Drosophila) (ROBO1) antibody
  • roundabout, axon guidance receptor, homolog 1 (robo1) antibody
  • roundabout, axon guidance receptor, homolog 1 (Drosophila) (robo1) antibody
  • RoBo-1 (LOC24906) antibody
  • roundabout homolog 1 (Drosophila) (Robo1) antibody
  • roundabout, axon guidance receptor, homolog 1 (Drosophila) (Robo1) antibody
  • AW494633 antibody
  • AW742721 antibody
  • DMT-1 antibody
  • DUTT1 antibody
  • Gm310 antibody
  • MGC122264 antibody
  • ROBO1 antibody
  • roundabout antibody
  • roundabout-1 antibody
  • SAX3 antibody

Protein level used designations for ROBO1

roundabout (axon guidance receptor, Drosophila) homolog 1 , roundabout, axon guidance receptor, homolog 1 (Drosophila) , Roundabout1 protein , roundabout-1 , roundabout 1 , roundabout homolog 1 , roundabout, axon guidance receptor, homolog 1 , roundabout homolog 1-like , divalent metal transporter-1 , protein RoBo-1 , rodent bone protein , deleted in U twenty twenty

GENE ID SPECIES
30769 Danio rerio
395292 Gallus gallus
399392 Xenopus laevis
460518 Pan troglodytes
536815 Bos taurus
722879 Macaca mulatta
100027473 Monodelphis domestica
100069075 Equus caballus
100124716 Xenopus (Silurana) tropicalis
100344245 Oryctolagus cuniculus
100387812 Callithrix jacchus
100459973 Pongo abelii
100517310 Sus scrofa
100545249 Meleagris gallopavo
100559253 Anolis carolinensis
100595092 Nomascus leucogenys
24906 Rattus norvegicus
19876 Mus musculus
6091 Homo sapiens
58946 Rattus norvegicus
487690 Canis lupus familiaris
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