Browse our anti-FFAR1 (FFAR1) Antibodies

Full name:
anti-Free Fatty Acid Receptor 1 Antibodies (FFAR1)
On are 95 Free Fatty Acid Receptor 1 (FFAR1) Antibodies from 18 different suppliers available. Additionally we are shipping FFAR1 Kits (21) and and many more products for this protein. A total of 126 FFAR1 products are currently listed.
FFA1R, FFAR1, GPCR40, Gpr40
list all antibodies Gene Name GeneID UniProt
FFAR1 2864 O14842
FFAR1 233081 Q76JU9
FFAR1 266607 Q8K3T4

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Most Popular Reactivities for anti-FFAR1 (FFAR1) Antibodies

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anti-Human FFAR1 Antibodies:

anti-Mouse (Murine) FFAR1 Antibodies:

anti-Rat (Rattus) FFAR1 Antibodies:

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Top referenced anti-FFAR1 Antibodies

  1. Human Polyclonal FFAR1 Primary Antibody for EIA, WB - ABIN952302 : Lu, Jiang, Lv, Wu, Yu, Zhu: Molecular docking and molecular dynamics simulation studies of GPR40 receptor-agonist interactions. in Journal of molecular graphics & modelling 2010 (PubMed)
    Show all 5 references for 952302

  2. Cow (Bovine) Polyclonal FFAR1 Primary Antibody for WB - ABIN2792205 : Sum, Tikhonova, Neumann, Engel, Raaka, Costanzi, Gershengorn: Identification of residues important for agonist recognition and activation in GPR40. in The Journal of biological chemistry 2007 (PubMed)

  3. Human Polyclonal FFAR1 Primary Antibody for ELISA, WB - ABIN185404 : Hardy, St-Onge, Joly, Langelier, Prentki: Oleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40. in The Journal of biological chemistry 2005 (PubMed)

  4. Human Polyclonal FFAR1 Primary Antibody for WB - ABIN656336 : Nagasumi, Esaki, Iwachidow, Yasuhara, Ogi, Tanaka, Nakata, Yano, Shimakawa, Taketomi, Takeuchi, Odaka, Kaisho: Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice. in Diabetes 2009 (PubMed)

More Antibodies against FFAR1 Interaction Partners

Human Free Fatty Acid Receptor 1 (FFAR1) interaction partners

  1. Comparison with an additional 2.2-A structure of the human GPR40-MK-8666 binary complex reveals an induced-fit conformational coupling between the partial agonist and AgoPAM binding sites, involving rearrangements of the transmembrane helices 4 and 5 (TM4 (show TPM4 Antibodies) and TM5) and transition of the intracellular loop 2 (ICL2) into a short helix.

  2. Results show that GPR40 negatively regulated the cell motile and invasive activities of HT1080 (show CDC123 Antibodies) cells suggesting that GPR40 negatively regulates the tumor progression of fibrosarcoma cells.

  3. Brain free long-chain fatty acids-GPR40/FFA1 signaling might have an important role in the modulation of endogenous pain control systems. (review)

  4. It regulates insulin (show INS Antibodies) secretion in pancreatic beta-cells. (review)

  5. Data from molecular docking simulations suggest that the binding pocket of GPR40 exhibits binding of free fatty acids (FFA) with chain lengths of C15 or fewer; for FFA with lengths longer than C15, part of alkyl chain extends out of binding pocket.

  6. GPR120 (show O3FAR1 Antibodies) negatively and GPR40 positively regulate cellular functions during tumor progression in lung cancer cells.

  7. Increased membrane permeability induced by linoleic acid is mediated by an intracellular signaling pathway activated by GPR40 that leads to an increase in membrane levels of Cx43 (show GJA1 Antibodies) phosphorylated at serine 373 via Akt (show AKT1 Antibodies).

  8. These data demonstrate that R104 in GPR40 is critically involved in the normal receptor functions. Interestingly, R104P is a registered single-nucleotide polymorphism of GPR40.

  9. Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120 (show O3FAR1 Antibodies)/FFA4

  10. results suggest that FFAR1 is the functionally dominant free fatty acid receptor in both human and guinea pig airway smooth muscle.

Mouse (Murine) Free Fatty Acid Receptor 1 (FFAR1) interaction partners

  1. These findings suggested that dysfunction of the GPR40/FFAR1 signaling pathway altered the endogenous pain control system and that this dysfunction might be associated with the development of chronic pain.

  2. Together, our data indicate effects of AgoPAMs that go beyond glucose lowering previously observed with GPR40 partial agonist treatment with additional potential for weight loss.

  3. These results support the hypothesis that mercaptoacetate stimulates food intake by blocking fatty acid effects on GPR40.

  4. These results indicated that GPR120 (show O3FAR1 Antibodies) enhanced and GPR40 inhibited the cell motile activity of highly migratory osteosarcoma cells.

  5. Results suggest that brain GPR40/FFAR1 is associated with anxiety- and depression-related behavior regulated by the increment of noradrenaline in the brain.

  6. Data revealed a weak influence of GPR40 agonist on osteoblast markers expression. Nevertheless, a significant increase in OPG (show TNFSF11 Antibodies) expression was observed upon GW9508 treatment that contribute to explain the GPR40-related osteoporosis prevention

  7. In the retinas of Vldlr (show VLDLR Antibodies)(-/-) mice with low fatty acid uptake but high circulating lipid levels, we found that Ffar1 suppresses expression of the glucose transporter Glut1 (show SLC2A1 Antibodies)

  8. activation of the hypothalamic GPR40/FFA1 signaling pathway may regulate beta-endorphin (show POMC Antibodies) release via PC2 (show CBX4 Antibodies), and regulate the endogenous pain control system

  9. These results suggest that both PPARgamma (show PPARG Antibodies) and GRP40 are required for RSG-induced inhibition of mouse calvaria osteoblast differentiation, which is mediated through GSK3beta (show GSK3b Antibodies)-dependent pathway.

  10. GPR40 signaling pathway plays an important suppressive role in spinal nociceptive processing after inflammation or nerve injury

FFAR1 Antigen Profile

Antigen Summary

This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes.

Alternative names and synonyms associated with FFAR1

  • free fatty acid receptor 1 (FFAR1) antibody
  • free fatty acid receptor 1 (Ffar1) antibody
  • FFA1R antibody
  • FFAR1 antibody
  • GPCR40 antibody
  • Gpr40 antibody

Protein level used designations for FFAR1

free fatty acid receptor 1 , G protein-coupled receptor 40 , G-protein coupled receptor 40 , G protein-coupled receptor GPR40

468836 Pan troglodytes
2864 Homo sapiens
233081 Mus musculus
266607 Rattus norvegicus
612661 Canis lupus familiaris
101834763 Mesocricetus auratus
100135676 Sus scrofa
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