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Chicken Polyclonal GCG Primary Antibody for IEM, ICC - ABIN617889
Pak, Cha, Rajotte, McArthur, Yoon: Human pancreatic islet cell specific 38 kilodalton autoantigen identified by cytomegalovirus-induced monoclonal islet cell autoantibody. in Diabetologia 1991
Show all 48 Pubmed References
Human Monoclonal GCG Primary Antibody for IHC (p) - ABIN3043073
Jiang, Deng, Duan, Chen, Xiang, Lu, Ma: Somatostatin receptors SSTR2 and SSTR5 are expressed in the human thoracic duct. in Lymphology 2011
Show all 6 Pubmed References
Human Monoclonal GCG Primary Antibody for CyTOF, FACS - ABIN4900763
Kornete, Beauchemin, Polychronakos, Piccirillo: Pancreatic islet cell phenotype and endocrine function throughout diabetes development in non-obese diabetic mice. in Autoimmunity 2013
Show all 3 Pubmed References
Human Polyclonal GCG Primary Antibody for ELISA, IF - ABIN2473808
Koistinaho, Hatanpää, Hervonen: Human paraganglion cells differentiate into adrenergic neurons in culture. in Experimental neurology 1990
Show all 3 Pubmed References
Human Polyclonal GCG Primary Antibody for ICC, IF - ABIN451504
Rovira, Scott, Liss, Jensen, Thayer, Leach: Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas. in Proceedings of the National Academy of Sciences of the United States of America 2010
Show all 2 Pubmed References
Human Monoclonal GCG Primary Antibody for ELISA, WB - ABIN966191
Geliebter, Hashim, Gluck: Appetite-related gut peptides, ghrelin, PYY, and GLP-1 in obese women with and without binge eating disorder (BED). in Physiology & behavior 2008
Show all 2 Pubmed References
Human Monoclonal GCG Primary Antibody for IF, IHC (p) - ABIN111416
Eissele, Göke, Willemer, Harthus, Vermeer, Arnold, Göke: Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. in European journal of clinical investigation 1992
Show all 2 Pubmed References
Human Polyclonal GCG Primary Antibody for ELISA - ABIN2473805
Woods, Lutz, Geary, Langhans: Pancreatic signals controlling food intake; insulin, glucagon and amylin. in Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2006
Human Polyclonal GCG Primary Antibody for RIA - ABIN2473807
Figueroa, Hess, Ky, Brown, Sandig, Hermanowski-Vosatka, Twells, Todd, Austin: Expression of the type I diabetes-associated gene LRP5 in macrophages, vitamin A system cells, and the Islets of Langerhans suggests multiple potential roles in diabetes. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000
Human Polyclonal GCG Primary Antibody for IF (p), IHC (p) - ABIN704246
Sun, Nie, Wang, Yang, Meng, Xiao, Xiang, Li, Fu, Wang: Factors that Affect Pancreatic Islet Cell Autophagy in Adult Rats: Evaluation of a Calorie-Restricted Diet and a High-Fat Diet. in PLoS ONE 2016
The findings indicate that the brainstem preproglucagon neuronal system is highly conserved between rat and non-human primate
CCK (show CCK Antibodies)/GLP-1 play contributory roles in anorexia induction by trichothecenes T-2 toxin, HT-2 toxin, diacetoxyscirpenol and neosolaniol.
The role of syntaxin 1A (show STX1A Antibodies) in GLP1 release from intestinal cells as a response to external stimuli is reported.
GLP (show GOLGA6A Antibodies)/G9a (show EHMT2 Antibodies) H3K9 methyltransferase complex is an enzyme counteracting Jmjd1a (show KDM3A Antibodies)-mediated H3K9 demethylation at the Sry (show SRY Antibodies) locus in gonadal somatic cells
GCG neurons likely stimulate separate populations of downstream cells to produce a change in food intake and glucose homeostasis and that these effects depend on the metabolic state of the animal.
miR (show MLXIP Antibodies)-217-mediated, genetic, or pharmacological inactivation of EHMT1 (show EHMT1 Antibodies)/2 was sufficient to promote pathological hypertrophy
Together, our data indicate effects of AgoPAMs that go beyond glucose lowering previously observed with GPR40 (show FFAR1 Antibodies) partial agonist treatment with additional potential for weight loss.
EHMT1 (show EHMT1 Antibodies) Mediates Homeostatic Synaptic Scaling
pancreatic reactivation of Gcg fully restored the effect of exendin-[9-39] to impair both oral and intraperitoneal glucose tolerance.
these findings identify distinct roles for DPP4 (show DPP4 Antibodies) in the endothelial cell versus the bone marrow compartment for selective incretin degradation and DPP4 (show DPP4 Antibodies) inhibition-mediated glucoregulation.
These findings suggest that TRPV2 (show TRPV2 Antibodies) activation via actin reorganization induced by Gq and G12 (show TCF3 Antibodies)/13 signaling is involved in LPI (show Slc7a7 Antibodies)-stimulated GLP-1 secretion in enteroendocrine L cells.
Age-dependent human beta cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling
Data suggest early peaks in glucagon-like peptide-1 and glucagon secretion/blood level together trigger exaggerated insulinotropic response (high insulin (show INS Antibodies) secretion/level) to eating and consequent hypoglycaemia in patients with postprandial hypoglycaemia as a postoperative complication following Roux-en-Y gastric bypass for obesity complicated by type 2 diabetes; this retrospective cohort study was conducted in London.
A common variant, i.e., single nucleotide polymorphism rs6741949, in the DPP4 (show DPP4 Antibodies) gene interacts with body adiposity and negatively affects glucose-stimulated GLP-1 levels, insulin (show INS Antibodies) secretion, and glucose tolerance.
Compared with the lean group, the obese group had significantly higher fasting and post-OGTT GIP (show GIP Antibodies) levels, but similar fasting GLP-1 and significantly lower post-OGTT GLP-1 levels.
Hemodialysis improves upper GI symptoms and gastric slow waves in CKD patients. An increase in ghrelin (show GHRL Antibodies) and a decrease in GLP-1 might be involved in the HD-induced improvement in gastric slow waves.
Data suggest that, in obesity, serum levels of active GLP1 are down-regulated and serum levels of soluble DPP4 (show DPP4 Antibodies) are up-regulated; DPP4 (show DPP4 Antibodies) levels correlate negatively with active GLP-1 levels but are positively associated with insulin (show INS Antibodies) resistance; thus, DPP4 (show DPP4 Antibodies) may be biomarker for insulin (show INS Antibodies) resistance. This study was conducted in Malaysia. (GLP1 = glucagon-like peptide 1; DPP4 (show DPP4 Antibodies) = dipeptidyl peptidase 4 (show DPP4 Antibodies))
Insulin (show INS Antibodies) resistance, postprandial GLP-1 and adaptive immunity are the main predictors of NAFLD (show TSC2 Antibodies) in a homogeneous population at high cardiovascular risk.
Data suggest that laparoscopic sleeve gastrectomy (LSG) for morbid obesity improves insulin resistance after either fast or slow feeding/eating; these findings suggest a negligible contribution of anorexigenic gut peptides GLP1 (glucagon-like peptide 1) and PYY (peptide YY) from intestinal L cells in response to LSG-induced weight loss.
missense variants in EHMT1 (show EHMT1 Antibodies) that lead to protein misfolding and disrupted histone mark binding can lead to Kleefstra Syndrome [case reports]
L-trp (show TBPL1 Antibodies) is a luminal regulator of CCK (show CCK Antibodies) release with effects on gastric emptying, an effect that could be mediated by CCK (show CCK Antibodies). L-trp's effect on GLP-1 secretion is only minor. At the doses given, the two amino acids did not affect subjective appetite feelings.
data demonstrate that cattle express proglucagon and glucagon-like peptide 2 receptor (show GLP2R Antibodies) mRNA primarily in small intestinal and colon tissues and increased nutrient intake increases ileal proglucagon mRNA and plasma glucagon-like peptide 2
Data suggest that casein, safflower oil, sucrose, and sweetening agent rebaudioside A stimulate GLP1 release/secretion from enteroendocrine cells. (GLP1 = glucagon-like peptide 1, a peptide fragment derived from proglucagon)
The patterns of colocalization of the K cell marker, glucagon-like insulinotropic peptide, and L cell markers, glucagon like peptide-1 and peptide YY, in enteroendocrine cells of the small intestine and colon of mouse and pig, were investigated.
Transcriptional repressor that plays a central role in somatic cells of the gonad and is required for germ cell development. Able to repress GATA transcription factor function (By similarity).
, preproglucagon B
, G9a-like protein 1
, euchromatic histone-lysine N-methyltransferase 1
, histone-lysine N-methyltransferase EHMT1
, lysine N-methyltransferase 1D
, G9a like protein
, H3-K9-HMTase 5
, histone H3-K9 methyltransferase 5
, histone-lysine N-methyltransferase, H3 lysine-9 specific 5
, glicentin-related polypeptide
, glucagon-like peptide 1
, glucagon-like peptide 2
, glucagon-like peptide I
, glucagon-like peptide-1
, glucagon I
, proglucagon I
, glucagon preproprotein
, preproglucagon A
, G protein-coupled receptor GLP2R
, GLP-2 receptor
, GLP II
, granzyme-like protein 2
, granzyme-like protein II
, mast cell protease X
, GATA like protein 1
, GATA like protein-1
, GATA zinc finger domain containing 3
, GATA-like protein 1
, GATA-type zinc finger protein 1