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GCG Products

(Glucagon (GCG))

Categories

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008].

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Featured GCG Categories

GCG Antibodies

High quality antibodies with extensive validation data.

GCG ELISA Kits

Reliable ELISA kits for a wide range of species.

GCG Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GCG Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (6)
Cat. No. ABIN390769
Quantity 400 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7429778
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7267392
Quantity 100 μL
Datasheet Datasheet

Recommended GCG ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6963535
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6956102
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
  • (7)
  • (1)
Cat. No. ABIN6956103
Quantity 96 tests
Datasheet Datasheet

Recommended GCG Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123099
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123098
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354908
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GCG products

Herzig, Studer, Nakas, Kuenzli, Stauffer, Hovorka, Bally: "Effect of fully automated closed-loop insulin delivery using faster aspart versus standard aspart on gluco-regulatory hormones in type 2 diabetes." in: Diabetes, obesity & metabolism, Vol. 23, Issue 1, pp. 228-233, (2021) (PubMed).

Xu, Wang, Guo, Liu, Zhang, Xu, Chen: "Emodin Alleviates Severe Acute Pancreatitis-Associated Acute Lung Injury by Inhibiting the Cold-Inducible RNA-Binding Protein (CIRP)-Mediated Activation of the NLRP3/IL-1β/CXCL1 Signaling." in: Frontiers in pharmacology, Vol. 12, pp. 655372, (2021) (PubMed).

Chen, Ren, Zhou, Deng, Hu, Zhang, Li: "HWL-088, a new potent free fatty acid receptor 1 (FFAR1) agonist, improves glucolipid metabolism and acts additively with metformin in ob/ob diabetic mice." in: British journal of pharmacology, Vol. 177, Issue 10, pp. 2286-2302, (2021) (PubMed).

Lin, Cheng, Du, Pan, Zhang, Wang, An, Yang, Xu, Lin, An, Wang, Yang, Chai, Sha, Hu, Sun, Yu: "In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals." in: Cell discovery, Vol. 6, pp. 20, (2020) (PubMed).

Huang, Li, Chen, Zhao, Huang, Zhou, Xu: "Identification of Potential Therapeutic Targets and Pathways of Liraglutide Against Type 2 Diabetes Mellitus (T2DM) Based on Long Non-Coding RNA (lncRNA) Sequencing." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 26, pp. e922210, (2020) (PubMed).

Lau, Corrales, Alexander, Mohammadi, Li, Smink, de Vos, Lakey: "Necrostatin-1 supplementation enhances young porcine islet maturation and in vitro function." in: Xenotransplantation, pp. e12555, (2019) (PubMed).

Li, Chang, Qiu, Chen, Zhang, Li, Cui: "Exogenous obestatin decreases beta-cell apoptosis and alfa-cell proliferation in high fat diet and streptozotocin induced type 2 diabetic rats." in: European journal of pharmacology, Vol. 851, pp. 36-42, (2019) (PubMed).

Elseweidy, Amin, Atteia, Aly: "Nigella sativa Oil and Chromium Picolinate Ameliorate Fructose-Induced Hyperinsulinemia by Enhancing Insulin Signaling and Suppressing Insulin-Degrading Enzyme in Male Rats." in: Biological trace element research, Vol. 184, Issue 1, pp. 119-126, (2018) (PubMed).

Xu, Bai, Chen, Li, Qin, Meng, Zhang: "6-Shogaol ameliorates diabetic nephropathy through anti-inflammatory, hyperlipidemic, anti-oxidative activity in db/db mice." in: Biomedicine & pharmacotherapy, Vol. 97, pp. 633-641, (2018) (PubMed).

Yang, Yan, Tong, Zhang, Chen, Xue, Wang, Chu, Jin, Li: "Chronic oscillating glucose challenges disarrange innate immune homeostasis to potentiate the variation of neutrophil-lymphocyte ratio in rats with or without hidden diabetes mellitus." in: Diabetes, metabolic syndrome and obesity : targets and therapy, Vol. 11, pp. 277-288, (2018) (PubMed).

Synonyms and alternative names related to GCG

glucagon (GCG), glucagon (Gcg), glucagon L homeolog (gcg.L), GCG, gcg-A, gcg1, GLP-1, GLP1, GLP2, Glu, GRPP, PPG

Protein level used designations for GCG

  • glicentin-related polypeptide
  • glucagon-like peptide 1
  • glucagon-like peptide 2
  • preproglucagon
  • glucagon-like peptide I
  • glucagon-like peptide-1
  • proglucagon
  • glucagon
  • preproglucagon B
  • glucagon preproprotein
  • preproglucagon A
  • glucagon I
  • glucagon-1
  • proglucagon I
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