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Browse our anti-LAX1 (LAX1) Antibodies

Full name:
anti-Lymphocyte Transmembrane Adaptor 1 Antibodies (LAX1)
On www.antibodies-online.com are 69 Lymphocyte Transmembrane Adaptor 1 (LAX1) Antibodies from 13 different suppliers available. Additionally we are shipping LAX1 Proteins (5) and many more products for this protein. A total of 84 LAX1 products are currently listed.
Synonyms:
A530029E09, E430019B13Rik, LAX

Most Popular Reactivities for anti-LAX1 (LAX1) Antibodies

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anti-Human LAX1 Antibodies:

anti-Mouse (Murine) LAX1 Antibodies:

anti-Rat (Rattus) LAX1 Antibodies:

All available anti-LAX1 Antibodies

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Top referenced anti-LAX1 Antibodies

  1. Cow (Bovine) Polyclonal LAX1 Primary Antibody for WB - ABIN2782914 : Zhu, Granillo, Wen, Yang, Dai, Wang, Zhang: Negative regulation of lymphocyte activation by the adaptor protein LAX. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)

  2. Human Polyclonal LAX1 Primary Antibody for ELISA - ABIN4330422 : Zhu, Janssen, Leung, Zhang: Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling. in The Journal of biological chemistry 2002 (PubMed)

More Antibodies against LAX1 Interaction Partners

Human Lymphocyte Transmembrane Adaptor 1 (LAX1) interaction partners

  1. TRIM (show TRAT1 Antibodies) required LAX for binding to Rab8 (show RAB8A Antibodies) in a complex, a novel CTLA-4 (show CTLA4 Antibodies)/TRIM (show TRAT1 Antibodies)/LAX/Rab8 (show RAB8A Antibodies) effector complex in the transport of CTLA-4 (show CTLA4 Antibodies) to the surfaces of T cells

  2. We identified the transmembrane domain of LAX as a first motif targeting transmembrane protein constructs to detergent-resistant heavy rafts, a novel type of membrane microdomains containing a number of physiologically important proteins.

  3. Overexpression of LAX in Jurkat cells specifically inhibits T cell receptor-mediated p38 MAPK (show MAPK14 Antibodies) activation and NFAT (show NFATC1 Antibodies)/AP-1 (show FOSB Antibodies) transcriptional activation.

  4. inhibition of signaling events involved in T cell activation by LAX occurs through mechanisms both dependent on and independent of its tyrosine phosphorylation.

Mouse (Murine) Lymphocyte Transmembrane Adaptor 1 (LAX1) interaction partners

  1. SIT and LAX are important negative regulators of immune responses that functionally cooperate.

  2. Upon T or B cell activation (show BLNK Antibodies), the LAX protein is up-regulated dramatically. This in vivo study of LAX-deficient mice demonstrates that LAX functions as a negative regulator in lymphocyte signaling.

  3. LAX negatively regulates mast cell function

LAX1 Antigen Profile

Antigen Summary

Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells (By similarity).

Alternative names and synonyms associated with LAX1

  • lymphocyte transmembrane adaptor 1 (LAX1) antibody
  • lymphocyte transmembrane adaptor 1 (LOC100359066) antibody
  • lymphocyte transmembrane adaptor 1 (Lax1) antibody
  • A530029E09 antibody
  • E430019B13Rik antibody
  • LAX antibody

Protein level used designations for LAX1

lymphocyte transmembrane adaptor 1 , lymphocyte transmembrane adapter 1-like , LAT-like membrane associated protein , linker for activation of x cells , lymphocyte transmembrane adapter 1 , membrane-associated adapter protein LAX , membrane associated adaptor protein LAX , linker for activation of X cells

GENE ID SPECIES
702011 Macaca mulatta
741370 Pan troglodytes
100359066 Oryctolagus cuniculus
100397361 Callithrix jacchus
100437319 Pongo abelii
100589202 Nomascus leucogenys
54900 Homo sapiens
540424 Bos taurus
240754 Mus musculus
498232 Rattus norvegicus
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