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LAT Antibodies

(Linker For Activation of T Cells (LAT))
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
LAT antibody LAT antibody LAT antibody (ABIN7074502)

LAT Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated

Recombinant LAT antibody  (pTyr191) Recombinant LAT antibody  (pTyr191) Recombinant LAT antibody (pTyr191) (ABIN7127705)

LAT Reactivity: Human WB, ELISA, IHC, IP, IF Host: Rabbit Monoclonal 2E4 unconjugated Recombinant Antibody

LAT antibody  (AA 30-237) LAT antibody  (AA 30-237) LAT antibody (AA 30-237) (ABIN1859615)

LAT Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

LAT Antibodies by Grade

Find LAT Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

LAT Antibodies by Reactivity

Find LAT Antibodies for a variety of species such as anti-Human LAT, anti-Mouse LAT, anti-Rat LAT. The species listed below are among those available. Click on a link to go to the corresponding products.

LAT Antibodies by Application

Find LAT Antibodies validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

LAT Antibodies by Host

Find LAT Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

LAT Antibodies by Binding Specificity

Find LAT Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

LAT Antibodies by Clonality

Find available monoclonal or polyclonal LAT Antibodies. Click on a link to go to the corresponding products.

LAT Antibodies by Clone

Find LAT Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

LAT Antibodies by Conjugate

Find LAT Antibodies with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 647, Biotin. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular LAT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN7074502
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP, IF
Validations
  • (5)
Cat. No. ABIN7127705
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN1859615
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN1868912
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN1868913
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP, FACS
Validations
  • (2)
  • (1)
Cat. No. ABIN302069
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN1386362
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN6256669
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, IHC (p)
Validations
  • (2)
Cat. No. ABIN293627
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN1531336
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7180039
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN3185361
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN3185362
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN185255
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6143099
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our LAT Antibodies

Carpier, Zucchetti, Bataille, Dogniaux, Shafaq-Zadah, Bardin, Lucchino, Maurin, Joannas, Magalhaes, Johannes, Galli, Goud, Hivroz: "Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation." in: The Journal of experimental medicine, Vol. 215, Issue 4, pp. 1245-1265, (2019) (PubMed).

Hrdinka, Dráber, Stepánek, Ormsby, Otáhal, Angelisová, Brdicka, Paces, Horejsí, Drbal: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).

Yamasaki, Ishikawa, Sakuma, Kanagawa, Cheng, Malissen, Saito: "LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival." in: Molecular and cellular biology, Vol. 27, Issue 12, pp. 4406-15, (2007) (PubMed).

Lebduska, Korb, T?mová, Heneberg, Dráber: "Topography of signaling molecules as detected by electron microscopy on plasma membrane sheets isolated from non-adherent mast cells." in: Journal of immunological methods, Vol. 328, Issue 1-2, pp. 139-51, (2007) (PubMed).

Heneberg, Lebduska, Dráberová, Korb, Dráber: "Topography of plasma membrane microdomains and its consequences for mast cell signaling." in: European journal of immunology, Vol. 36, Issue 10, pp. 2795-806, (2006) (PubMed).

Tedoldi, Paterson, Hansmann, Natkunam, Rüdiger, Angelisova, Du, Roberton, Roncador, Sanchez, Pozzobon, Masir, Barry, Pileri, Mason, Marafioti, Horejsí: "Transmembrane adaptor molecules: a new category of lymphoid-cell markers." in: Blood, Vol. 107, Issue 1, pp. 213-21, (2005) (PubMed).

Cho, Velikovsky, Swaminathan, Houtman, Samelson, Mariuzza: "Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads." in: The EMBO journal, Vol. 23, Issue 7, pp. 1441-51, (2004) (PubMed).

Volná, Lebduska, Dráberová, Símová, Heneberg, Boubelík, Bugajev, Malissen, Wilson, Horejsí, Malissen, Dráber: "Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL." in: The Journal of experimental medicine, Vol. 200, Issue 8, pp. 1001-13, (2004) (PubMed).

Simeoni, Smida, Posevitz, Schraven, Lindquist: "Right time, right place: the organization of membrane proximal signaling." in: Seminars in immunology, Vol. 17, Issue 1, pp. 35-49, (2004) (PubMed).

Janssen, Zhang: "Adaptor proteins in lymphocyte activation." in: Current opinion in immunology, Vol. 15, Issue 3, pp. 269-76, (2003) (PubMed).

Aliases for LAT Antibodies

linker for activation of T-cells (LAT) Antibodies
linker for activation of T cells (lat) Antibodies
linker for activation of T cells (Lat) Antibodies
LAT Antibodies
lat Antibodies
LAT1 Antibodies
pp36 Antibodies
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