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LAX1 antibody (C-Term)

LAX1 Reactivity: Human, Mouse, Rat, Pig, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787949
  • Target See all LAX1 Antibodies
    LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Pig, Dog
    Host
    • 26
    • 2
    • 2
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    This LAX1 antibody is un-conjugated
    Application
    • 25
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    ADFQPFTQSE DSQMKHREEM SNEDSSDYEN VLTAKLGGRD SEQGPGTQLL
    Predicted Reactivity
    Dog: 86%, Human: 100%, Mouse: 79%, Pig: 79%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against LAX1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human LAX1
    Top Product
    Discover our top product LAX1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 382 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))
    Alternative Name
    LAX1 (LAX1 Products)
    Synonyms
    LAX antibody, A530029E09 antibody, E430019B13Rik antibody, lymphocyte transmembrane adaptor 1 antibody, LAX1 antibody, Lax1 antibody
    Background
    LAX1 is a single-pass type III membrane protein. It negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
    Alias Symbols: FLJ20340, LAX
    Protein Interaction Partner: STAMBPL1, GRB7, NDN, UBC, GRAP2, SYK, ZAP70, LCK, GRB2,
    Protein Size: 382
    Molecular Weight
    42 kDa
    Gene ID
    54900
    NCBI Accession
    NM_001136190, NP_001129662
    UniProt
    B7Z744
    Pathways
    Production of Molecular Mediator of Immune Response
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