Browse our NAD Dependent Malate Dehydrogenase Proteins (NAD-ME)

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NAD Dependent Malate Dehydrogenase Proteins (NAD-ME)
On are 5 NAD Dependent Malate Dehydrogenase (NAD-ME) Proteins from 4 different suppliers available. Additionally we are shipping NAD Dependent Malate Dehydrogenase Antibodies (34) and NAD Dependent Malate Dehydrogenase Kits (4) and many more products for this protein. A total of 47 NAD Dependent Malate Dehydrogenase products are currently listed.
A1, AA408400, ALF2, AW120568, AW209082, bHLHb21, D030040L20Rik, E2A, E12, E12/E47, E47, ME2, NAD-ME, ODS1, Pan1, Pan2, Tcfe2a, VDIR
list all proteins Gene Name GeneID UniProt
NAD-ME 4200 P23368
Rat NAD-ME NAD-ME 307270  
NAD-ME 107029 Q99KE1

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NAD Dependent Malate Dehydrogenase Proteins (NAD-ME) by Origin

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More Proteins for NAD Dependent Malate Dehydrogenase Interaction Partners

Human NAD Dependent Malate Dehydrogenase (NAD-ME) interaction partners

  1. deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer

  2. ME1 (show ME1 Proteins)/ME2 expression phenotype may have a potential to be a valuable marker for sebaceous differentiation in sebaceous lesions.

  3. Data indicate that malic enzyme 2 knockdown impacts phosphatidylinositol 3-kinases/proto-oncogene (show RAB1A Proteins) protein akt (show AKT1 Proteins) (PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins)) signaling.

  4. ME2 might be an important factor in melanoma progression and a novel biomarker of invasion.

  5. Three SNP alleles in BRD2 (show BRD2 Proteins), Cx-36 (show GJD2 Proteins), and ME2 and microdeletions in 15q13.3, 15q11.2, and 16p13.11 also contribute risk to juvenile myclonic epilepsy.

  6. p53 (show TP53 Proteins) represses the expression of the tricarboxylic-acid-cycle-associated malic enzymes ME1 (show ME1 Proteins) and ME2 in human and mouse cells

  7. Depletion of malic enzyme 2 induced erythroid differentiation in human erythroleukemia cells.

  8. An ME2-centered nine-SNP haplotype, when present homozygously, increases the risk for IGE (odds ratio 6.1; 95% confidence interval 2.9-12.7) compared with any other genotype

  9. Schizophrenic subjects are identified with mitochondrial genes involved in oxidative metabolism as showing consistently decreased expression, including ME2.

  10. Single nucleotide polymorphism in ME2 gene is associated with acute lymphoblastic leukemia.

Mouse (Murine) NAD Dependent Malate Dehydrogenase (NAD-ME) interaction partners

  1. If Gfi1 (show ZNF163 Proteins) levels fall below a threshold, Id1 (show ID1 Proteins) expression increases and renders E2A (show TCF3 Proteins) unable to function, which prevents hematopoietic progenitors from engaging along the B lymphoid lineage

  2. these data identified E2A (show TCF3 Proteins) and E2-2 (show TCF4 Proteins) as central regulators of B cell immunity.

  3. down-regulation of Id3 (show ID3 Proteins) in B cells is essential for releasing E2A (show TCF3 Proteins) and E2-2 (show TCF4 Proteins), which in a redundant manner are required for antigen-induced B cell differentiation.

  4. deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer

  5. Data suggest a novel mechanism of drug resistance in which E2a (show TCF3 Proteins) and PRC2 drive changes in the B-cell epigenome; these alterations attenuate alkylating agent treatment-induced apoptosis.

  6. These findings suggest that miR (show MLXIP Proteins)-506-3p played an important role in regulating NSC proliferation and differentiation via targeting TCF3 (show TCF7L1 Proteins), and provide a promising avenue for future in-depth research into the functions of miR (show MLXIP Proteins)-506-3p and TCF3 (show TCF7L1 Proteins) in nervous system development.

  7. Conditional expression of E2A (show TCF3 Proteins)-HLF (show HLF Proteins) induces B-cell precursor death and myeloproliferative-like disease in knock-in mice.

  8. Upregulation of E12/E47 by HBx ultimately and concomitant repression of E-cadherin (show CDH1 Proteins) expression led to epithelial-mesenchymal transition in human hepatocytes.

  9. Mechanistically, E47 (show TCF3 Proteins) repressed the expression of several astrocyte-specific genes in adult NSPCs.

  10. Tcf3 (show TCF7L1 Proteins) is upregulated in skin wounds and Tcf3 (show TCF7L1 Proteins) overexpression accelerates keratinocyte migration and skin wound healing.

NAD Dependent Malate Dehydrogenase (NAD-ME) Protein Profile

Protein Summary

This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

Alternative names and synonyms associated with NAD Dependent Malate Dehydrogenase (NAD-ME)

  • malic enzyme 2, NAD(+)-dependent, mitochondrial (ME2)
  • malic enzyme 2, NAD(+)-dependent, mitochondrial (me2)
  • malic enzyme 2, NAD(+)-dependent, mitochondrial (Me2)
  • transcription factor 3 (Tcf3)
  • A1 protein
  • AA408400 protein
  • ALF2 protein
  • AW120568 protein
  • AW209082 protein
  • bHLHb21 protein
  • D030040L20Rik protein
  • E2A protein
  • E12 protein
  • E12/E47 protein
  • E47 protein
  • ME2 protein
  • NAD-ME protein
  • ODS1 protein
  • Pan1 protein
  • Pan2 protein
  • Tcfe2a protein
  • VDIR protein

Protein level used designations for NAD-ME

NAD-ME , NAD-dependent malic enzyme, mitochondrial , malate dehydrogenase , pyruvic-malic carboxylase , malic enzyme 2 , TCF-3 , immunoglobulin enhancer-binding factor E12/E47 , transcription factor A1 , transcription factor E2-alpha , transcription factor E2a

4200 Homo sapiens
398584 Xenopus laevis
476198 Canis lupus familiaris
507817 Bos taurus
307270 Rattus norvegicus
107029 Mus musculus
21423 Mus musculus
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