Anaphase Promoting Complex Subunit 5 (ANAPC5) (AA 2-232), (partial) protein (GST tag)

Details for Product No. ABIN1046518
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Protein Name
Protein Characteristics
AA 2-232, partial
Origin
Human
(5), (1), (1)
Source
Escherichia coli (E. coli)
(3), (2), (2)
Protein Type Recombinant
Purification tag / Conjugate
This ANAPC5 protein is labelled with GST tag.
Application
ELISA, SDS-PAGE (SDS)
Pubmed 2 references available
Quantity 1 mg
Options
Shipping to United States ( )
Availability Will be delivered in 9 to 11 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Sequence ASVHESLYFN PMMTNGVVHA NVFGIKDWVT PYKIAVLVLL NEMSRTGEGA VSLMERRRLN QLLLPLLQGP DITLSKLYKL IEESCPQLAN SVQIRIKLMA EGELKDMEQF FDDLSDSFSG TEPEVHKTSV VGLFLRHMIL AYSKLSFSQV FKLYTALQQY FQNGEKKTVE DADMELTSRD EGERKMEKEE LDVSVREEEV SCSGPLSQKQ AEFFLSQQAS LLKNDETKAL T
Characteristics Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Ref.7
Purity 90 %
Alternative Name Anaphase-promoting complex subunit 5
Background Synonyms: APC5,Cyclosome subunit 5
Molecular Weight 53.6 kD
UniProt Q9UJX4
Comment

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions For Research Use only
Format Lyophilized
Buffer PBS buffer, 20mM GSH
Storage -20 °C
Supplier Images
Anaphase Promoting Complex Subunit 5 (ANAPC5) (AA 2-232), (partial) protein (GST tag) Anaphase Promoting Complex Subunit 5 (ANAPC5) (AA 2-232), (partial) protein (GST tag)
Background publications Kraft, Herzog, Gieffers et al.: "Mitotic regulation of the human anaphase-promoting complex by phosphorylation." in: The EMBO journal, Vol. 22, Issue 24, pp. 6598-609, 2003 (PubMed).

Yu, Peters, King et al.: "Identification of a cullin homology region in a subunit of the anaphase-promoting complex." in: Science (New York, N.Y.), Vol. 279, Issue 5354, pp. 1219-22, 1998 (PubMed).

Validation Images
Catalog No. ABIN1046518
1,842.50 $
Plus shipping costs $45.00
Quantity
Price
1 mg
1,842.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)