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Browse our TMSB4X Proteins (TMSB4X)

Full name:
Thymosin beta-4 Proteins (TMSB4X)
On are 23 Thymosin beta-4 (TMSB4X) Proteins from 7 different suppliers available. Additionally we are shipping TMSB4X Antibodies (62) and TMSB4X Kits (27) and many more products for this protein. A total of 125 TMSB4X products are currently listed.
FX, Ptmb4, Tb4, TB4X, TMSB4, TMSB4X
list all proteins Gene Name GeneID UniProt
TMSB4X 7114 P62328
TMSB4X 81814 P62329
TMSB4X 19241 P20065

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TMSB4X Proteins (TMSB4X) by Origin

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Human Thymosin beta-4 (TMSB4X) interaction partners

  1. Tbeta4 gene silencing in A549 and H1299 cells inhibited cell proliferation, migration, and invasion in vitro and decreased tumor growth in vivo. Mechanistic investigations revealed a significant decrease in Notch1 (show NOTCH1 Proteins) activation in Tbeta4 gene-silenced cells.

  2. Developed an innovative biotechnological method for thymosin beta4 production that employs the peptide acetylation in vivo.

  3. Serum thymosin beta4 concentrations were correlated with the occurrence and severity of obstructive sleep apnea syndrome.

  4. this study demonstrated, for the first time, that Tbeta4 was down-regulated in ROS (show ROS1 Proteins)-stimulated PDLCs as well as Tbeta4 activation exhibited anti-inflammatory effects and anti-osteoclastogenesis in vitro.

  5. This article reviews the potential role of thymosin beta 4 in liver fibrosis by describing the effects of exogenous and endogenous thymosin beta 4 , and discusses the possible signaling pathway regulated by TB4X. [review]

  6. The results of the present study suggested that Tb4 may promote HB metastasis via the induction of EMT (show ITK Proteins), and that Tb4 may therefore be a target for the development of novel treatments for patients with Hepatoblastoma .

  7. these results suggest that NO could regulate the expression of Tbeta4 by direct or indirect effect of HIF-1alpha (show HIF1A Proteins) on Tbeta4 promoter.

  8. the exchange of bound actin between Tbeta4 and profilin (show PFN1 Proteins) involves both steric and allosteric components.

  9. Thymosin beta4 induces invasion and migration of human colorectal cancer cells through the ILK (show ILK Proteins)/AKT (show AKT1 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway.

  10. Regarding HCC (show FAM126A Proteins), Tbeta4 reactivity was detected in 7/23 cases (30%) and Tbeta10 reactivity in 22/23 (97%) cases analyzed, adding HCC (show FAM126A Proteins) to human cancers that express these beta-thymosins.

Cow (Bovine) Thymosin beta-4 (TMSB4X) interaction partners

  1. TMSB4 and/or TMSB10 (show TMSB10 Proteins) ovarian expression patterns suggest that these two thymosins may be involved in cumulus modifications during maturation.

Horse (Equine) Thymosin beta-4 (TMSB4X) interaction partners

Mouse (Murine) Thymosin beta-4 (TMSB4X) interaction partners

  1. Increased Tb4 expression was observed in ethanol treated microglia. Knockdown of Tb4 enhanced ethanol-induced inflammatory mediators tumor necrosis factor-alpha and interleukin-1beta and nitric oxide in BV-2 cells was performed.

  2. Results provide evidence that Tbeta4 regulate the levels of VEGF (show VEGFA Proteins) and MMP-2 (show MMP2 Proteins) via the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins)/Lef-1 (show LEF1 Proteins) signaling pathway to influence the growth of blood vessels around hair follicles and to activate cell migration.

  3. this study demonstrated, for the first time, that Tbeta4 was down-regulated in ROS (show ROS1 Proteins)-stimulated PDLCs as well as Tbeta4 activation exhibited anti-inflammatory effects and anti-osteoclastogenesis in vitro.

  4. Tbeta4 appears to regulate P38/ERK (show MAPK1 Proteins)/AKT (show AKT1 Proteins) signaling via its effect on VEGF (show VEGFA Proteins) expression, with a resultant effect on the speed of hair growth, the pattern of HFs and the number of hair shafts

  5. This study provides putative information concerning the signaling pathway through which Tb4 induces RUNX2 (show RUNX2 Proteins) expression, which may help to understand the regulation of tooth development and tooth regeneration.

  6. Tbeta4 substantially inhibited bleomycin-induced IL-17 (show IL17A Proteins) over-expression in the lung tissue: a decreased amount of IL17 (show IL17A Proteins)-producing cells and inhibited IL-17 (show IL17A Proteins) expression in lung with Tbeta4 treatment correlate with its anti-inflammatory and anti-fibrotic effects.

  7. These data suggest that Tbeta4 suppresses the TLR proinflammatory pathway by up-regulating miR (show MLXIP Proteins)-146a.

  8. Thymosin beta4 may play a role in aging-related hearing loss.

  9. These data show that thymosinbeta4 and beta-actin are over-expressed during nurse cell formation upon T. spiralis infection and may be involved in nurse cell formation along with other actin-binding proteins.

  10. Thymosin beta4 is a novel endothelial secreted trophic factor that functions synergistically with TGFbeta (show TGFB1 Proteins) to regulate mural cell development and vascular wall stability.

TMSB4X Protein Profile

Protein Summary

This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y.

Alternative names and synonyms associated with TMSB4X

  • thymosin beta 4 (LOC100860922)
  • thymosin beta 4 peptide (tmsb4x)
  • thymosin beta 4, X-linked (TMSB4X)
  • thymosin beta 4, X-linked (Tmsb4x)
  • thymosin beta 4, X-linked (TMSB4)
  • thymosin, beta 4-like (LOC100339394)
  • thymosin, beta 4, X chromosome (Tmsb4x)
  • FX protein
  • Ptmb4 protein
  • Tb4 protein
  • TB4X protein
  • TMSB4 protein
  • TMSB4X protein

Protein level used designations for Thymosin beta-4 Proteins (TMSB4X)

t beta 4 , thymosin beta 4Xen , thymosin beta-4 , prothymosin beta-4 , t beta-4 , thymosin, beta 4, X chromosome , seraspenide , thymosin beta 4 X-linked , thymosin b4 , thymosin, beta 4 , thymosin, beta 4, X-linked , thymosin beta 4, X-linked , prothymosin beta 4

100860922 Capra hircus
399438 Xenopus laevis
7114 Homo sapiens
100736168 Cavia porcellus
733606 Sus scrofa
781334 Bos taurus
100034015 Equus caballus
408047 Gallus gallus
100339394 Oryctolagus cuniculus
81814 Rattus norvegicus
19241 Mus musculus
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