Browse our PGAM1 Proteins (PGAM1)

On www.antibodies-online.com are 20 phosphoglycerate Mutase 1 (Brain) (PGAM1) Proteins from 8 different suppliers available. Additionally we are shipping PGAM1 Antibodies (71) and PGAM1 Kits (25) and many more products for this protein. A total of 122 PGAM1 products are currently listed.
Synonyms:
2310050F24Rik, MGC81450, Pgam-1, PGAM-B, PGAM1, PGAMA, Pgmut
list all proteins Gene Name GeneID UniProt
PGAM1 18648 Q9DBJ1
PGAM1 5223 P18669
PGAM1 24642 P25113

PGAM1 Proteins (PGAM1) by Origin

More Proteins for PGAM1 Interaction Partners

Mouse (Murine) phosphoglycerate Mutase 1 (Brain) (PGAM1) interaction partners

  1. PGAM1 correlates with spermatogenic dysfunction and affects the function of cell proliferation, apoptosis and migration.

  2. 9630033F20Rik (show C12orf5 Proteins) may play an important role in muscle wasting and that it has a distinguished characterization of gene network.[9630033F20Rik (show C12orf5 Proteins)]

  3. histidine-phosphorylated PGAM1 correlated with expression of PKM2 in tumor tissues; decreased pyruvate kinase activity in PKM2-expressing cells allows PEP-dep (show PREP Proteins)endent histidine phosphorylation of PGAM1 and may provide an alternate glycolytic pathway

Human phosphoglycerate Mutase 1 (Brain) (PGAM1) interaction partners

  1. When BPGM (show BPGM Proteins) is knocked out, 1,3-BPG can directly phosphorylate PGAM1. In this case, PGAM1 phosphorylation and activity are decreased, but nevertheless sufficient to maintain normal glycolytic flux and cellular growth rate.

  2. study provided the first evidence revealing a non-metabolic function of PGAM1 in promoting cell migration, and gained new insights into the role of PGAM1 in cancer progression.

  3. Data show that tyrosine 26 phosphorylation enhances the binding of phosphoglycerate mutase 1 (PGAM1) to its substrates through generating electrostatic environment and structural features that are advantageous to the binding.

  4. PGAM1 in promoting homologous recombination repair in tumor cell lines. Suggest potential therapeutic opportunity for PGAM1 inhibitors in combination with PARP inhibitors in cancer treatment.

  5. PGAM1 may be associated with the grade of glioma and be involved in the biological behavior of glioma cells. PGAM1 might be a novel therapeutic target in glioma.

  6. PGAM1 correlates with spermatogenic dysfunction and affects the function of cell proliferation, apoptosis and migration.

  7. Our finding showed that PGAM1 might serve as a promising therapeutic target for UBC (show RPS27A Proteins).

  8. PGAM1 is highly expressed in clear cell renal cell carcinoma (show MOK Proteins) and correlated with clinicalpathological features, which may contribute to tumor formation and progression.

  9. PGAM is acetylated at lysines 100/106/113/138 in its central region, and a member of the Sirtuin (show SIRT1 Proteins) family (class III deacetylase), SIRT2 (show SIRT2 Proteins), is responsible for its deacetylation.

  10. Tyrosine26 phosphorylation represents an additional acute mechanism underlying phosphoglycerate mutase 1 upregulation.

PGAM1 Protein Profile

Protein Summary

Phosphoglyceric acid mutase (EC 2.7.5.3) is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway (summary by Chen et al., 1974

Alternative names and synonyms associated with PGAM1

  • phosphoglycerate mutase 1 (brain) (pgam1)
  • phosphoglycerate mutase 1 (brain) (PGAM1)
  • phosphoglycerate mutase 1 (LOC100350706)
  • phosphoglycerate mutase 1 (Pgam1)
  • phosphoglycerate mutase 1 (brain) (Pgam1)
  • phosphoglycerate mutase 1-like (LOC100352195)
  • phosphoglycerate mutase 1-like (LOC100154776)
  • 2310050F24Rik protein
  • MGC81450 protein
  • Pgam-1 protein
  • PGAM-B protein
  • PGAM1 protein
  • PGAMA protein
  • Pgmut protein

Protein level used designations for PGAM1

phosphoglycerate mutase 1 (brain) , phosphoglycerate mutase 1 , uncharacterized protein LOC706211 , BPG-dependent PGAM 1 , PGAM-B , phosphoglycerate mutase isozyme B , phosphoglycerate mutase A, nonmuscle form

GENE ID SPECIES
432058 Xenopus laevis
450650 Pan troglodytes
694418 Macaca mulatta
695799 Macaca mulatta
696959 Macaca mulatta
706211 Macaca mulatta
100144939 Xenopus (Silurana) tropicalis
100350706 Oryctolagus cuniculus
18648 Mus musculus
404148 Bos taurus
5223 Homo sapiens
24642 Rattus norvegicus
477786 Canis lupus familiaris
428969 Gallus gallus
100718830 Cavia porcellus
100174215 Pongo abelii
100352195 Oryctolagus cuniculus
100154776 Sus scrofa
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