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PHLPP2 Proteins

(PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor.
PHLPP2 Protein (AA 766-1043) (His tag) PHLPP2 Protein (AA 766-1043) (His tag) PHLPP2 Protein (AA 766-1043) (His tag) (ABIN7124383)

PHLPP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

PHLPP2 Protein (AA 1-1323) (Strep Tag) (ABIN3094545)

PHLPP2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, ELISA, SDS

PHLPP2 Protein (AA 1-1320) (Strep Tag) (ABIN3136302)

PHLPP2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, ELISA, SDS

PHLPP2 Proteins by Origin

Find PHLPP2 Proteins for a variety of species such as anti-Human PHLPP2, anti-Mouse PHLPP2. The species listed below are among those available. Click on a link to go to the corresponding products.

PHLPP2 Proteins by Source

Here you will find PHLPP2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PHLPP2 Proteins by Protein Type

Here you can find PHLPP2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

PHLPP2 Proteins by Application

Find PHLPP2 Proteins validated for a specific application such as WB, ELISA, SDS, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PHLPP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124383
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094545
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136302
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2728850
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6700357
Quantity 50 μg
Datasheet Datasheet

Aliases for PHLPP2 Proteins

PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) Proteins
PH domain and leucine rich repeat protein phosphatase 2 S homeolog (phlpp2.S) Proteins
PH domain and leucine rich repeat protein phosphatase 2 (phlpp2) Proteins
PH domain and leucine rich repeat protein phosphatase 2 (Phlpp2) Proteins
AI481772 Proteins
C130044A18Rik Proteins
PHLPPL Proteins
phlppl Proteins
Phlppl Proteins
RGD1562857 Proteins
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