Browse our Immunoglobulin lambda-Like Polypeptide 1 Proteins (IGLL1)

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Immunoglobulin lambda-Like Polypeptide 1 Proteins (IGLL1)
On www.antibodies-online.com are 8 Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) Proteins from 5 different suppliers available. Additionally we are shipping Immunoglobulin lambda-Like Polypeptide 1 Antibodies (96) and many more products for this protein. A total of 115 Immunoglobulin lambda-Like Polypeptide 1 products are currently listed.
Synonyms:
14.1, AGM2, BB139905, CD179b, Igl-5, IGL1, IGL5, IGLJ14.1, Igll, Igll1, IGLV, IGO, IGVPB, Lambda5, MGC151892, Vpreb-2, VpreB1, VPREB2
list all proteins Gene Name GeneID UniProt
Rat IGLL1 IGLL1 100360919  
IGLL1 3543 P15814
IGLL1 16136 P20764

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Immunoglobulin lambda-Like Polypeptide 1 Proteins (IGLL1) by Origin

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Top referenced Immunoglobulin lambda-Like Polypeptide 1 Proteins

  1. Human IGLL1 Protein expressed in Escherichia coli (E. coli) - ABIN1098784 : Bankovich, Raunser, Juo, Walz, Davis, Garcia: Structural insight into pre-B cell receptor function. in Science (New York, N.Y.) 2007 (PubMed)
    Show all 2 references for 1098784

More Proteins for Immunoglobulin lambda-Like Polypeptide 1 Interaction Partners

Human Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) interaction partners

  1. Irrespective of subtype, Acute Lymphoblastic Leukemia with high levels of IGHM, IGLL1 and VPREB1 (show VPREB1 Proteins) are arrested at the pre-B stage and correlate with good prognosis in high-risk pediatric B-cell precursor acute lymphoblastic leukemia.

  2. Hhydrophobic residues from the lambda5-UR is crucial for the interaction with GAL1 (show LGALS1 Proteins) and for pre-BCR (show BCR Proteins) clustering.

Mouse (Murine) Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) interaction partners

  1. Data show no autoantibody production was detectable in surrogate light chain (SLC (show CCL21A Proteins)) components VpreB/CD179a (show VPREB1 Proteins) and lambda5/CD179b transgenic mice.

  2. VpreB probes the fitness of newly generated VH domains of IgH chains for later pairing with IgL chains, and its non-Ig part fixes the preBCRs on the surface.

  3. Mice triply deficient for VpreB2 show B cell developmental defects but functional allelic exclusion of the IgH locus.

  4. Data demonstrate that the pre-B-cell receptor is essential for monoallelic silencing of VpreB (show VPREB1 Proteins) and lambda5 at the large pre-BII (show CACNA1E Proteins)-cell stage.

Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) Protein Profile

Protein Summary

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Immunoglobulin lambda-Like Polypeptide 1 (IGLL1)

  • immunoglobulin lambda-like polypeptide 1 (IGLL1)
  • Immunoglobulin lambda-like polypeptide 1-like (LOC100360919)
  • immunoglobulin lambda-like polypeptide 1 (Igll1)
  • pre-B lymphocyte gene 2 (Vpreb2)
  • 14.1 protein
  • AGM2 protein
  • BB139905 protein
  • CD179b protein
  • Igl-5 protein
  • IGL1 protein
  • IGL5 protein
  • IGLJ14.1 protein
  • Igll protein
  • Igll1 protein
  • IGLV protein
  • IGO protein
  • IGVPB protein
  • Lambda5 protein
  • MGC151892 protein
  • Vpreb-2 protein
  • VpreB1 protein
  • VPREB2 protein

Protein level used designations for IGLL1

Ig lambda chain V-1 region , Ig light chain variable region , immunoglobulin lambda-like polypeptide 1 , Lambda5 , Immunoglobulin lambda-like polypeptide 1-like , CD179 antigen-like family member B , CD179b antigen , Pre-B lymphocyte-specific protein-2 , ig lambda-5 , immunoglobulin omega polypeptide chain , immunoglobulin-related 14.1 protein , immunoglobulin-related protein 14.1 , lambda5 , immunoglobulin lambda chain 5 , lambda 5 , Lambda 5 , immunoglobulin omega chain

GENE ID SPECIES
416928 Gallus gallus
720135 Macaca mulatta
789205 Bos taurus
100008913 Oryctolagus cuniculus
100360919 Rattus norvegicus
3543 Homo sapiens
16136 Mus musculus
22363 Mus musculus
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